Gene Page: SH3GL1

Summary
GeneID  6455
Symbol  SH3GL1
Synonyms  CNSA1|EEN|MGC111371|SH3D2B|SH3P8
Description  SH3-domain GRB2-like 1
See related  HGNC:10830|MIM:601768|Ensembl:ENSG00000141985|HPRD:03462|
Locus tag  -
Gene type  protein-coding
Map location  19p13.3
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
NetworkShortest path distance of core genes in the Human protein-protein interaction networkContribution to shortest path in PPI network: 0.0081 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
PLK40.920.90
RBL10.920.84
DNA20.920.86
NCAPG20.910.91
KNTC10.910.90
CEP1920.910.89
POLA10.900.88
MCM40.900.93
MCM80.900.80
WDR760.900.88
Top 10 negatively co-expressed genes
AF347015.31-0.63-0.87
MT-CO2-0.62-0.88
FXYD1-0.61-0.86
HLA-F-0.61-0.75
AF347015.27-0.61-0.83
AF347015.33-0.60-0.83
AIFM3-0.60-0.75
MT-CYB-0.60-0.83
IFI27-0.60-0.84
S100B-0.59-0.79
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005515protein bindingIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005737cytoplasmIEA-
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
ARHGAP8BPGAP1 | FLJ20185 | PP610Rho GTPase activating protein 8BPGAP1 interacts with EEN.BIND15944398 
DNM1DNMdynamin 1-HPRD,BioGRID9238017 |10764144 
DPPA42410091M23Rik | FLJ10713developmental pluripotency associated 4Two-hybridBioGRID16169070 
PDCD6IPAIP1 | Alix | DRIP4 | HP95 | MGC17003programmed cell death 6 interacting protein-HPRD12034747 
SH2D4AFLJ20967 | SH2ASH2 domain containing 4ATwo-hybridBioGRID16189514 
SH3D19EBP | EVE1 | Kryn | MGC105136 | MGC118910 | MGC118911 | MGC118912 | MGC118913 | SH3P19SH3 domain containing 19-HPRD14551139 
SH3GL1CNSA1 | EEN | MGC111371 | SH3D2B | SH3P8SH3-domain GRB2-like 1Two-hybridBioGRID16189514 
SH3GL3CNSA3 | EEN-2B-L3 | EEN-B2 | HsT19371 | SH3D2C | SH3P13SH3-domain GRB2-like 3Two-hybridBioGRID16169070 
SH3KBP1CIN85 | GIG10 | MIG18SH3-domain kinase binding protein 1Endophilin A2 interacts with CIN85. This interaction was modeled on a demonstrated interaction between endophilin A2 from an unspecified species and human CIN85.BIND11894096 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_ENDOCYTOSIS 183132All SZGR genes in this pathway
PID_FAK_PATHWAY 5945All SZGR genes in this pathway
MULLIGHAN_NPM1_MUTATED_SIGNATURE_1_UP 276165All SZGR genes in this pathway
MULLIGHAN_NPM1_MUTATED_SIGNATURE_2_UP 13983All SZGR genes in this pathway
MULLIGHAN_NPM1_SIGNATURE_3_UP 341197All SZGR genes in this pathway
ENK_UV_RESPONSE_KERATINOCYTE_UP 530342All SZGR genes in this pathway
DELYS_THYROID_CANCER_UP 443294All SZGR genes in this pathway
WANG_ESOPHAGUS_CANCER_VS_NORMAL_DN 10166All SZGR genes in this pathway
RICKMAN_METASTASIS_DN 261155All SZGR genes in this pathway
CROMER_METASTASIS_DN 8158All SZGR genes in this pathway
ACEVEDO_LIVER_CANCER_UP 973570All SZGR genes in this pathway
BONOME_OVARIAN_CANCER_SURVIVAL_OPTIMAL_DEBULKING 246152All SZGR genes in this pathway
GRADE_COLON_CANCER_UP 871505All SZGR genes in this pathway
GRADE_COLON_AND_RECTAL_CANCER_UP 285167All SZGR genes in this pathway
GRESHOCK_CANCER_COPY_NUMBER_UP 323240All SZGR genes in this pathway
ICHIBA_GRAFT_VERSUS_HOST_DISEASE_35D_UP 13179All SZGR genes in this pathway
KIM_ALL_DISORDERS_OLIGODENDROCYTE_NUMBER_CORR_UP 756494All SZGR genes in this pathway
BRUINS_UVC_RESPONSE_VIA_TP53_GROUP_B 549316All SZGR genes in this pathway
KRIEG_HYPOXIA_NOT_VIA_KDM3A 770480All SZGR genes in this pathway
VANOEVELEN_MYOGENESIS_SIN3A_TARGETS 220133All SZGR genes in this pathway
HOLLEMAN_VINCRISTINE_RESISTANCE_B_ALL_UP 3822All SZGR genes in this pathway


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