Gene Page: ST8SIA1

Summary
GeneID  6489
Symbol  ST8SIA1
Synonyms  GD3S|SIAT8|SIAT8A|ST8SiaI
Description  ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
See related  HGNC:10869|MIM:601123|Ensembl:ENSG00000111728|HPRD:03078|
Locus tag  -
Gene type  protein-coding
Map location  12p12.1-p11.2
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
ExpressionExpressionP value: 1.654 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
HDAC70.850.88
CHTF180.790.68
SH3BP20.790.80
SCRIB0.790.77
LRP50.790.80
AC005005.30.780.76
SUV420H20.780.73
SBNO20.780.83
LEPRE10.780.70
MUTYH0.780.71
Top 10 negatively co-expressed genes
ACOT13-0.60-0.69
ITM2B-0.59-0.65
ACYP2-0.57-0.66
TPMT-0.55-0.62
FAM162A-0.55-0.64
HIGD1A-0.55-0.65
OMG-0.55-0.63
CLYBL-0.55-0.62
CISD1-0.55-0.64
C5orf53-0.55-0.59
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0003828alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activityIEA-
GO:0016757transferase activity, transferring glycosyl groupsIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006486protein amino acid glycosylationIEA-
GO:0005975carbohydrate metabolic processTAS8195250 
GO:0008284positive regulation of cell proliferationIEA-
GO:0006688glycosphingolipid biosynthetic processTAS8195250 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0000139Golgi membraneIEA-
GO:0005794Golgi apparatusIEA-
GO:0016020membraneIEA-
GO:0016021integral to membraneTAS8195250 
GO:0030173integral to Golgi membraneIEA-
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_GLYCOSPHINGOLIPID_BIOSYNTHESIS_LACTO_AND_NEOLACTO_SERIES 2619All SZGR genes in this pathway
KEGG_GLYCOSPHINGOLIPID_BIOSYNTHESIS_GLOBO_SERIES 1412All SZGR genes in this pathway
KEGG_GLYCOSPHINGOLIPID_BIOSYNTHESIS_GANGLIO_SERIES 159All SZGR genes in this pathway
SENGUPTA_NASOPHARYNGEAL_CARCINOMA_WITH_LMP1_DN 17582All SZGR genes in this pathway
DEURIG_T_CELL_PROLYMPHOCYTIC_LEUKEMIA_DN 320184All SZGR genes in this pathway
TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_8D_DN 205127All SZGR genes in this pathway
KIM_WT1_TARGETS_12HR_UP 162116All SZGR genes in this pathway
FARMER_BREAST_CANCER_BASAL_VS_LULMINAL 330215All SZGR genes in this pathway
KIM_MYCN_AMPLIFICATION_TARGETS_UP 9264All SZGR genes in this pathway
BENPORATH_SUZ12_TARGETS 1038678All SZGR genes in this pathway
BENPORATH_EED_TARGETS 1062725All SZGR genes in this pathway
BYSTRYKH_HEMATOPOIESIS_STEM_CELL_AND_BRAIN_QTL_TRANS 185114All SZGR genes in this pathway
SHIPP_DLBCL_VS_FOLLICULAR_LYMPHOMA_DN 4528All SZGR genes in this pathway
BLALOCK_ALZHEIMERS_DISEASE_UP 16911088All SZGR genes in this pathway
BANDRES_RESPONSE_TO_CARMUSTIN_WITHOUT_MGMT_48HR_UP 1813All SZGR genes in this pathway
GAVIN_FOXP3_TARGETS_CLUSTER_P3 160103All SZGR genes in this pathway
ZHENG_BOUND_BY_FOXP3 491310All SZGR genes in this pathway
ZHENG_FOXP3_TARGETS_IN_T_LYMPHOCYTE_DN 3729All SZGR genes in this pathway
KONDO_PROSTATE_CANCER_HCP_WITH_H3K27ME3 9772All SZGR genes in this pathway
HELLER_SILENCED_BY_METHYLATION_UP 282183All SZGR genes in this pathway
SMID_BREAST_CANCER_RELAPSE_IN_BRAIN_UP 3920All SZGR genes in this pathway
SMID_BREAST_CANCER_RELAPSE_IN_BONE_DN 315197All SZGR genes in this pathway
SMID_BREAST_CANCER_LUMINAL_B_DN 564326All SZGR genes in this pathway
SMID_BREAST_CANCER_BASAL_UP 648398All SZGR genes in this pathway
YOSHIMURA_MAPK8_TARGETS_UP 1305895All SZGR genes in this pathway
RUTELLA_RESPONSE_TO_CSF2RB_AND_IL4_UP 338225All SZGR genes in this pathway
RUTELLA_RESPONSE_TO_HGF_UP 418282All SZGR genes in this pathway
RUTELLA_RESPONSE_TO_HGF_VS_CSF2RB_AND_IL4_DN 245150All SZGR genes in this pathway
VANTVEER_BREAST_CANCER_ESR1_DN 240153All SZGR genes in this pathway
HOELZEL_NF1_TARGETS_DN 11573All SZGR genes in this pathway
PURBEY_TARGETS_OF_CTBP1_NOT_SATB1_DN 448282All SZGR genes in this pathway
GOBERT_OLIGODENDROCYTE_DIFFERENTIATION_DN 1080713All SZGR genes in this pathway
RAO_BOUND_BY_SALL4_ISOFORM_B 517302All SZGR genes in this pathway


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