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GeneID |
6493
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Symbol |
SIM2
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Synonyms |
MGC119447|SIM|bHLHe15
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Description |
single-minded homolog 2 (Drosophila) |
See related |
HGNC:10883|MIM:600892|Ensembl:ENSG00000159263|HPRD:02935| |
Locus tag |
- |
Gene type |
protein-coding |
Map location |
21q22.2|21q22.13 |
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Gene set name |
Method of gene set |
Evidence |
Info |
GO_Annotation | Mapping neuro-related keywords to Gene Ontology annotations | Hits with neuro-related keywords: 1 | |
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General Gene Expression (microarray) ? |
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Gene Expression in Brain Regions (new) |
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Top co-expressed genes in Brain Regions (new) |
|
Gene | Pearson's Correlation | Spearman's Correlation | | |
Top 10 positively co-expressed genes |
AFAP1L2 | 0.81 | 0.85 | | |
TMEM184B | 0.80 | 0.84 | | |
PER3 | 0.79 | 0.85 | | |
TOM1L2 | 0.79 | 0.81 | | |
CTSA | 0.79 | 0.84 | | |
SIRPA | 0.78 | 0.87 | | |
MAP3K5 | 0.78 | 0.84 | | |
SYT15 | 0.77 | 0.80 | | |
TSPAN7 | 0.77 | 0.81 | | |
SLC20A2 | 0.77 | 0.84 | | |
Top 10 negatively co-expressed genes | RPS13P2 | -0.54 | -0.63 | | |
RPL24 | -0.54 | -0.66 | | |
RPS23 | -0.53 | -0.64 | | |
RPS3AP47 | -0.53 | -0.63 | | |
RPL31 | -0.53 | -0.63 | | |
RPL27 | -0.52 | -0.62 | | |
RPS8 | -0.52 | -0.62 | | |
UXT | -0.52 | -0.61 | | |
RPS27A | -0.52 | -0.66 | | |
RPS6 | -0.52 | -0.63 | | |
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Molecular function | GO term | Evidence | Neuro keywords | PubMed ID |
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GO:0004871 | signal transducer activity | IEA | | - |
GO:0003700 | transcription factor activity | TAS | | 8661114 |9199934 |
GO:0005515 | protein binding | IEA | | - |
GO:0016564 | transcription repressor activity | IEA | | - |
GO:0046982 | protein heterodimerization activity | IEA | | - |
Biological process | GO term | Evidence | Neuro keywords | PubMed ID |
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GO:0007399 | nervous system development | TAS | neurite (GO term level: 5) | 9199934 |
GO:0000122 | negative regulation of transcription from RNA polymerase II promoter | IEA | | - |
GO:0006355 | regulation of transcription, DNA-dependent | IEA | | - |
GO:0007165 | signal transduction | IEA | | - |
GO:0009880 | embryonic pattern specification | IEA | | - |
GO:0007275 | multicellular organismal development | IEA | | - |
GO:0030154 | cell differentiation | IEA | | - |
GO:0030324 | lung development | IEA | | - |
Cellular component | GO term | Evidence | Neuro keywords | PubMed ID |
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GO:0005634 | nucleus | IEA | | - |
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- SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
- Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.
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