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GeneID |
6496
|
Symbol |
SIX3
|
Synonyms |
HPE2
|
Description |
SIX homeobox 3 |
See related |
HGNC:10889|MIM:603714|Ensembl:ENSG00000138083|HPRD:04756| |
Locus tag |
- |
Gene type |
protein-coding |
Map location |
2p16-p21 |
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Gene set name |
Method of gene set |
Evidence |
Info |
GO_Annotation | Mapping neuro-related keywords to Gene Ontology annotations | Hits with neuro-related keywords: 1 | |
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General Gene Expression (microarray) ? |
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Gene Expression in Brain Regions (new) |
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Top co-expressed genes in Brain Regions (new) |
|
Gene | Pearson's Correlation | Spearman's Correlation | | |
Top 10 positively co-expressed genes |
COL1A2 | 0.86 | 0.46 | | |
OGN | 0.85 | 0.45 | | |
COL1A1 | 0.85 | 0.47 | | |
COL3A1 | 0.85 | 0.47 | | |
OSR1 | 0.84 | 0.42 | | |
COL6A3 | 0.84 | 0.47 | | |
BNC2 | 0.83 | 0.35 | | |
SCARA5 | 0.82 | 0.39 | | |
GJB2 | 0.81 | 0.33 | | |
ALX4 | 0.81 | 0.43 | | |
Top 10 negatively co-expressed genes | LHPP | -0.27 | -0.16 | | |
C5orf53 | -0.25 | -0.27 | | |
REEP6 | -0.25 | -0.14 | | |
HLA-C | -0.25 | -0.20 | | |
HEPN1 | -0.24 | -0.19 | | |
AF347015.33 | -0.24 | -0.27 | | |
MT-CO2 | -0.24 | -0.29 | | |
AF347015.31 | -0.24 | -0.28 | | |
TSC22D4 | -0.24 | -0.20 | | |
MRPL41 | -0.24 | -0.17 | | |
|
Molecular function | GO term | Evidence | Neuro keywords | PubMed ID |
---|
GO:0003705 | RNA polymerase II transcription factor activity, enhancer binding | IEA | | - |
GO:0005515 | protein binding | IEA | | - |
GO:0016564 | transcription repressor activity | IEA | | - |
GO:0043565 | sequence-specific DNA binding | IEA | | - |
Biological process | GO term | Evidence | Neuro keywords | PubMed ID |
---|
GO:0007420 | brain development | TAS | Brain (GO term level: 7) | 10369266 |
GO:0006355 | regulation of transcription, DNA-dependent | IEA | | - |
GO:0007601 | visual perception | TAS | | 10369266 |
GO:0007275 | multicellular organismal development | IEA | | - |
GO:0016481 | negative regulation of transcription | IEA | | - |
GO:0030178 | negative regulation of Wnt receptor signaling pathway | IEA | | - |
GO:0043010 | camera-type eye development | IEA | | - |
Cellular component | GO term | Evidence | Neuro keywords | PubMed ID |
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GO:0005634 | nucleus | IEA | | - |
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- SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
- Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.
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