Gene Page: SLC18A1

Summary
GeneID  6570
Symbol  SLC18A1
Synonyms  CGAT|VAT1|VMAT1
Description  solute carrier family 18 (vesicular monoamine), member 1
See related  HGNC:10934|MIM:193002|Ensembl:ENSG00000036565|HPRD:01897|
Locus tag  -
Gene type  protein-coding
Map location  8p21.3
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
AssociationA combined odds ratio method (Sun et al. 2008), association studies2Link to SZGene
GSMA_Igenome scan meta-analysisPsr: 0.031 
GSMA_IIEgenome scan meta-analysis (European-ancestry samples)Psr: 0.00057 
GSMA_IIAgenome scan meta-analysis (All samples)Psr: 0.03086 
LiteratureHigh-throughput literature-searchCo-occurance with Schizophrenia keywords: [schizophrenias, schizophrenia]Click to show detail
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
LRRC510.720.52
CCDC74A0.690.48
TCTN10.690.55
CCDC74B0.670.51
C9orf240.670.53
PPOX0.670.65
C9orf1160.660.43
C1orf1940.650.53
FAM181A0.640.39
C9orf90.640.54
Top 10 negatively co-expressed genes
PRKG2-0.31-0.32
CDKL5-0.31-0.26
LMBRD2-0.31-0.27
JHDM1D-0.31-0.28
TRIM44-0.30-0.36
FBXW7-0.29-0.26
PCLO-0.29-0.22
AP000758.2-0.29-0.27
USP12-0.28-0.28
KIAA1462-0.28-0.38
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0008504monoamine transmembrane transporter activityTAS8643547 
GO:0015238drug transporter activityIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0015844monoamine transportTAS8643547 
GO:0015893drug transportIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005624membrane fractionNAS-
GO:0016020membraneIEA-
GO:0016021integral to membraneIEA-
GO:0031410cytoplasmic vesicleIEA-
GO:0030659cytoplasmic vesicle membraneIEA-
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_PARKINSONS_DISEASE 13378All SZGR genes in this pathway
REACTOME_TRANSMEMBRANE_TRANSPORT_OF_SMALL_MOLECULES 413270All SZGR genes in this pathway
REACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT 241157All SZGR genes in this pathway
REACTOME_TRANSPORT_OF_GLUCOSE_AND_OTHER_SUGARS_BILE_SALTS_AND_ORGANIC_ACIDS_METAL_IONS_AND_AMINE_COMPOUNDS 8954All SZGR genes in this pathway
REACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS 1712All SZGR genes in this pathway
REACTOME_AMINE_COMPOUND_SLC_TRANSPORTERS 2716All SZGR genes in this pathway
BARRIER_COLON_CANCER_RECURRENCE_UP 4228All SZGR genes in this pathway
GRAESSMANN_APOPTOSIS_BY_SERUM_DEPRIVATION_UP 552347All SZGR genes in this pathway
CONCANNON_APOPTOSIS_BY_EPOXOMICIN_DN 172112All SZGR genes in this pathway
GRAESSMANN_APOPTOSIS_BY_DOXORUBICIN_UP 1142669All SZGR genes in this pathway
GRAESSMANN_RESPONSE_TO_MC_AND_DOXORUBICIN_UP 612367All SZGR genes in this pathway
TARTE_PLASMA_CELL_VS_PLASMABLAST_UP 398262All SZGR genes in this pathway
HOEGERKORP_CD44_TARGETS_TEMPORAL_DN 2516All SZGR genes in this pathway
CHANG_IMMORTALIZED_BY_HPV31_UP 8455All SZGR genes in this pathway
YAGI_AML_WITH_INV_16_TRANSLOCATION 422277All SZGR genes in this pathway
HOELZEL_NF1_TARGETS_UP 13993All SZGR genes in this pathway


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