Gene Page: SLIT1

Summary
GeneID  6585
Symbol  SLIT1
Synonyms  MEGF4|MGC164811|SLIL1|SLIT3|Slit-1
Description  slit homolog 1 (Drosophila)
See related  HGNC:11085|MIM:603742|Ensembl:ENSG00000187122|HPRD:04773|
Locus tag  RP11-175O19.2
Gene type  protein-coding
Map location  10q23.3-q24
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 3 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
PABPN10.910.88
LUC7L0.900.90
AKAP8L0.890.91
C1orf350.890.89
SFRS160.880.85
AL049829.30.880.90
SFRS80.870.87
HIRIP30.870.89
SAFB20.860.90
ACIN10.860.88
Top 10 negatively co-expressed genes
AF347015.31-0.64-0.77
B2M-0.63-0.72
AF347015.27-0.61-0.76
C5orf53-0.59-0.66
MT-CO2-0.59-0.74
MT-CYB-0.59-0.73
AF347015.33-0.59-0.72
COPZ2-0.57-0.67
PSMB9-0.56-0.67
SRGN-0.56-0.68
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005509calcium ion bindingNAS-
GO:0005515protein bindingTAS9813312 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0007420brain developmentTASBrain (GO term level: 7)10432110 
GO:0031290retinal ganglion cell axon guidanceIEAaxon, Brain (GO term level: 14)-
GO:0007399nervous system developmentTASneurite (GO term level: 5)9813312 
GO:0007275multicellular organismal developmentIEA-
GO:0030154cell differentiationIEA-
GO:0040023establishment of nucleus localizationIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005576extracellular regionIEA-
GO:0005615extracellular spaceTAS9813312 
GO:0005737cytoplasmIDA18029348 
GO:0043231intracellular membrane-bounded organelleIDA18029348 
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
GPC1FLJ38078 | glypicanglypican 1-HPRD10364234 
ROBO1DUTT1 | FLJ21882 | MGC131599 | MGC133277 | SAX3roundabout, axon guidance receptor, homolog 1 (Drosophila)-HPRD10433822 
 


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