Gene Page: SNRPD1

Summary
GeneID  6632
Symbol  SNRPD1
Synonyms  HsT2456|SMD1|SNRPD
Description  small nuclear ribonucleoprotein D1 polypeptide 16kDa
See related  HGNC:11158|MIM:601063|Ensembl:ENSG00000167088|HPRD:03040|
Locus tag  -
Gene type  protein-coding
Map location  18q11.2
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
NetworkShortest path distance of core genes in the Human protein-protein interaction networkContribution to shortest path in PPI network: 0.1289 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
ABCG20.740.75
APOL30.740.79
GBP10.730.80
CARD60.720.70
TNFSF100.710.73
CFB0.710.76
APOL10.710.74
IFIH10.710.77
ABCB10.700.73
NMI0.700.75
Top 10 negatively co-expressed genes
ZNF821-0.66-0.69
ACTL6B-0.64-0.68
DPF1-0.63-0.66
DGCR14-0.63-0.67
DAZAP1-0.63-0.66
GFOD2-0.63-0.66
DBN1-0.62-0.65
INO80B-0.62-0.67
C7orf26-0.62-0.64
MPP3-0.62-0.65
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0003723RNA bindingTAS3260384 
GO:0005515protein bindingIPI11714716 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0000245spliceosome assemblyTAS7527560 
GO:0000387spliceosomal snRNP biogenesisEXP15130578 
GO:0008380RNA splicingTAS1701240 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005829cytosolEXP10531003 
GO:0005634nucleusTAS3260384 
GO:0005654nucleoplasmEXP10531003 
GO:0005681spliceosomeIEA-
GO:0005737cytoplasmIEA-
GO:0030532small nuclear ribonucleoprotein complexTAS7527560 
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
CLNS1ACLCI | CLNS1B | IClnchloride channel, nucleotide-sensitive, 1AAffinity Capture-Western
Reconstituted Complex		BioGRID11713266 
DDX20DKFZp434H052 | DP103 | GEMIN3DEAD (Asp-Glu-Ala-Asp) box polypeptide 20-HPRD,BioGRID10601333 
GEMIN5DKFZp586M1824 | MGC142174gem (nuclear organelle) associated protein 5-HPRD,BioGRID11714716 
LSM10MGC15749 | MST074 | MSTP074LSM10, U7 small nuclear RNA associatedAffinity Capture-MSBioGRID12975319 
LSM11FLJ38273LSM11, U7 small nuclear RNA associated-HPRD12975319 
LSM8YJR022WLSM8 homolog, U6 small nuclear RNA associated (S. cerevisiae)-HPRD,BioGRID15231747 
PRMT5HRMT1L5 | IBP72 | JBP1 | SKB1 | SKB1Hsprotein arginine methyltransferase 5-HPRD,BioGRID11713266 
RNU11U11RNA, U11 small nuclearAffinity Capture-MSBioGRID15146077 
RNU12U12RNA, U12 small nuclearAffinity Capture-MSBioGRID15146077 
SF3A2PRP11 | PRPF11 | SAP62 | SF3a66splicing factor 3a, subunit 2, 66kDaAffinity Capture-MSBioGRID12234937 
SFRS12DKFZp564B176 | MGC133045 | SRrp508 | SRrp86splicing factor, arginine/serine-rich 12-HPRD14559993 
SMN1BCD541 | SMA | SMA1 | SMA2 | SMA3 | SMA4 | SMA@ | SMN | SMNT | T-BCD541survival of motor neuron 1, telomericCo-fractionation
Co-purification
Reconstituted Complex		BioGRID9323129 |10851237 
|10942426 
SMN2BCD541 | C-BCD541 | FLJ76644 | MGC20996 | MGC5208 | SMNCsurvival of motor neuron 2, centromeric-HPRD9323129 |10942426 
SNRPD2SMD2 | SNRPD1small nuclear ribonucleoprotein D2 polypeptide 16.5kDaCo-crystal Structure
Two-hybrid		BioGRID9417867 |10025403 
SNRPD2 interacts with SNRPD1.BIND9417867 
SNRPNDKFZp686C0927 | DKFZp686M12165 | DKFZp761I1912 | DKFZp762N022 | FLJ33569 | FLJ36996 | FLJ39265 | HCERN3 | MGC29886 | PWCR | RT-LI | SM-D | SMN | SNRNP-N | SNURF-SNRPNsmall nuclear ribonucleoprotein polypeptide NSNRPN interacts with SNRPD1.BIND9417867 
WDR77HKMT1069 | MEP50 | MGC2722 | Nbla10071 | RP11-552M11.3 | p44WD repeat domain 77-HPRD,BioGRID11756452 
 
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-4864652m8hsa-miR-486UCCUGUACUGAGCUGCCCCGAG
miR-4955763m8hsa-miR-495brainAAACAAACAUGGUGCACUUCUUU
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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