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Association Linkage Expression Literature GO_Annotation Gene Network miRNA Targets

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Association Linkage Expression Literature GO_Annotation Gene Network miRNA Targets Datasets Gene Ranking

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Gene Page: STAU1

Summary

GeneID

6780

Symbol

STAU1

Synonyms

FLJ25010|STAU

Description

staufen, RNA binding protein, homolog 1 (Drosophila)

Locus tag

RP3-470L14.2

Gene type

protein-coding

Map location

20q13.1

Gene in Data Sources

Gene set name

Method of gene set

Evidence

Info

Network

Shortest path distance of core genes in the Human protein-protein interaction network

Contribution to shortest path in PPI network: 0.0179

General Gene Expression (microarray) ?

Gene Expression in Brain Regions (new)

Top co-expressed genes in Brain Regions (new)

Gene

Pearson's Correlation

Spearman's Correlation

Top 10 positively co-expressed genes

LGALS1

0.53

0.57

AGPAT2

0.51

0.53

MRPL41

0.50

0.53

MSRB2

0.50

0.57

PVALB

0.49

0.55

CRYBA2

0.48

0.53

SDF2L1

0.48

0.42

SMPX

0.47

0.43

SNCG

0.46

0.52

DAPL1

0.46

0.37

Top 10 negatively co-expressed genes

AOF1

-0.42

-0.57

THOC2

-0.42

-0.59

MAP4K4

-0.42

-0.55

PTPN1

-0.42

-0.56

GNB4

-0.42

-0.57

PHF3

-0.41

-0.57

LATS1

-0.41

-0.57

TOP1

-0.41

-0.58

RSF1

-0.41

-0.56

HP1BP3

-0.41

-0.55

Gene Ontology

Molecular function

GO term

Evidence

Neuro keywords

PubMed ID

GO:0003725

double-stranded RNA binding

IEA

GO:0003725

double-stranded RNA binding

TAS

10022909

GO:0005515

protein binding

IPI

15303970 |15680326

Biological process

GO term

Evidence

Neuro keywords

PubMed ID

GO:0008298

intracellular mRNA localization

IEA

Cellular component

GO term

Evidence

Neuro keywords

PubMed ID

GO:0005791

rough endoplasmic reticulum

TAS

10022909

GO:0005875

microtubule associated complex

TAS

10022909

GO:0005622

intracellular

IEA

GO:0030529

ribonucleoprotein complex

IEA

Interactions

Shown by Network

Interactors	Aliases B	Official full name B	Experimental	Source	PubMed ID
ARF1	-	ADP-ribosylation factor 1	Stau1 interacts with Arf1.	BIND	15680326
CASC3	BTZ \| MLN51	cancer susceptibility candidate 3	Stau1 interacts with Barentsz. This interaction was modeled on a demonstrated interaction between human Stau1 and monkey Barentsz.	BIND	15680326
CASC3	BTZ \| MLN51	cancer susceptibility candidate 3	-	HPRD	12843282
NCBP1	CBP80 \| MGC2087 \| NCBP	nuclear cap binding protein subunit 1, 80kDa	Stau1 interacts with CBP80. This interaction was modeled on a demonstrated interaction between human Stau1 and monkey CBP80.	BIND	15680326
PAICS	ADE2 \| ADE2H1 \| AIRC \| DKFZp781N1372 \| MGC1343 \| MGC5024 \| PAIS	phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase	Stau1 interacts with PAICS.	BIND	15680326
UPF1	FLJ43809 \| FLJ46894 \| HUPF1 \| KIAA0221 \| NORF1 \| RENT1 \| pNORF1	UPF1 regulator of nonsense transcripts homolog (yeast)	Upf1 interacts with Stau1.	BIND	15680326

Pathway annotation

Pathway name	Pathway size	# SZGR genes in pathway	Info
LIU_SOX4_TARGETS_DN	309	191	All SZGR genes in this pathway
DIAZ_CHRONIC_MEYLOGENOUS_LEUKEMIA_UP	1382	904	All SZGR genes in this pathway
GINESTIER_BREAST_CANCER_20Q13_AMPLIFICATION_UP	119	66	All SZGR genes in this pathway
ENK_UV_RESPONSE_KERATINOCYTE_DN	485	334	All SZGR genes in this pathway
GRAESSMANN_APOPTOSIS_BY_DOXORUBICIN_UP	1142	669	All SZGR genes in this pathway
MARTORIATI_MDM4_TARGETS_FETAL_LIVER_DN	514	319	All SZGR genes in this pathway
WILLIAMS_ESR2_TARGETS_UP	28	18	All SZGR genes in this pathway
KOYAMA_SEMA3B_TARGETS_UP	292	168	All SZGR genes in this pathway
STARK_PREFRONTAL_CORTEX_22Q11_DELETION_DN	517	309	All SZGR genes in this pathway
SHEN_SMARCA2_TARGETS_UP	424	268	All SZGR genes in this pathway
BYSTRYKH_HEMATOPOIESIS_STEM_CELL_QTL_TRANS	882	572	All SZGR genes in this pathway
PENG_RAPAMYCIN_RESPONSE_DN	245	154	All SZGR genes in this pathway
BLALOCK_ALZHEIMERS_DISEASE_UP	1691	1088	All SZGR genes in this pathway
JIANG_HYPOXIA_NORMAL	311	205	All SZGR genes in this pathway
MARTINEZ_RESPONSE_TO_TRABECTEDIN_DN	271	175	All SZGR genes in this pathway
GRADE_COLON_CANCER_UP	871	505	All SZGR genes in this pathway

miRNA Targets ?

miRNA family	Target position			miRNA ID	miRNA seq
miRNA family	UTR start	UTR end	Match method	miRNA ID	miRNA seq
miR-142-3p	1039	1046	1A,m8	hsa-miR-142-3p	UGUAGUGUUUCCUACUUUAUGGA
miR-142-3p	1039	1046	1A,m8	hsa-miR-142-3p	UGUAGUGUUUCCUACUUUAUGGA
miR-142-5p	1498	1505	1A,m8	hsa-miR-142-5p	CAUAAAGUAGAAAGCACUAC
miR-326	458	464	1A	hsa-miR-326	CCUCUGGGCCCUUCCUCCAG
miR-330	60	67	1A,m8	hsa-miR-330^brain	GCAAAGCACACGGCCUGCAGAGA
miR-361	80	86	m8	hsa-miR-361^brain	UUAUCAGAAUCUCCAGGGGUAC
miR-381	859	865	1A	hsa-miR-381	UAUACAAGGGCAAGCUCUCUGU
miR-486	1043	1049	1A	hsa-miR-486	UCCUGUACUGAGCUGCCCCGAG
miR-495	1360	1366	1A	hsa-miR-495^brain	AAACAAACAUGGUGCACUUCUUU

SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.