Gene Page: VAMP1

Summary
GeneID  6843
Symbol  VAMP1
Synonyms  DKFZp686H12131|SYB1|VAMP-1
Description  vesicle-associated membrane protein 1 (synaptobrevin 1)
See related  HGNC:12642|MIM:185880|Ensembl:ENSG00000139190|HPRD:01716|
Locus tag  -
Gene type  protein-coding
Map location  12p
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 1 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
COPZ10.840.82
C8orf410.830.83
DAP30.820.81
SPG210.820.81
CNBP0.820.79
CHCHD30.810.78
PRMT50.810.77
EIF3I0.810.80
USP390.810.80
VPS450.810.80
Top 10 negatively co-expressed genes
AF347015.8-0.69-0.67
MT-CO2-0.69-0.67
AF347015.27-0.68-0.68
AF347015.21-0.66-0.64
AF347015.2-0.66-0.68
MT-CYB-0.66-0.66
AF347015.15-0.65-0.67
AF347015.31-0.65-0.66
AF347015.26-0.64-0.66
AF347015.33-0.64-0.64
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005515protein bindingIPI9920726 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0016192vesicle-mediated transportIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0019717synaptosomeIEASynap, Brain (GO term level: 7)-
GO:0045202synapseIEAneuron, Synap, Neurotransmitter, Glial (GO term level: 2)-
GO:0005739mitochondrionIEA-
GO:0005741mitochondrial outer membraneIEA-
GO:0016020membraneIEA-
GO:0005887integral to plasma membraneTAS1976629 
GO:0030054cell junctionIEA-
GO:0031410cytoplasmic vesicleIEA-
GO:0030659cytoplasmic vesicle membraneIEA-
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
SNAP23HsT17016 | SNAP23A | SNAP23Bsynaptosomal-associated protein, 23kDa-HPRD8663154 
STX1AHPC-1 | STX1 | p35-1syntaxin 1A (brain)Two-hybridBioGRID12093152 
STX1BSTX1B1 | STX1B2syntaxin 1B-HPRD,BioGRID12093152 
STX4STX4A | p35-2syntaxin 4Two-hybridBioGRID8760387 
VAPAMGC3745 | VAP-33 | VAP-A | VAP33 | hVAP-33VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa-HPRD,BioGRID9657962 
VAPBALS8 | VAMP-B | VAMP-C | VAP-B | VAP-CVAMP (vesicle-associated membrane protein)-associated protein B and C-HPRD,BioGRID9920726 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_SNARE_INTERACTIONS_IN_VESICULAR_TRANSPORT 3825All SZGR genes in this pathway
REACTOME_BOTULINUM_NEUROTOXICITY 1914All SZGR genes in this pathway
REACTOME_PROTEOLYTIC_CLEAVAGE_OF_SNARE_COMPLEX_PROTEINS 1712All SZGR genes in this pathway
REACTOME_NEURONAL_SYSTEM 279221All SZGR genes in this pathway
KORKOLA_SEMINOMA_UP 4427All SZGR genes in this pathway
CASORELLI_ACUTE_PROMYELOCYTIC_LEUKEMIA_UP 177110All SZGR genes in this pathway
GAL_LEUKEMIC_STEM_CELL_DN 244153All SZGR genes in this pathway
OSMAN_BLADDER_CANCER_DN 406230All SZGR genes in this pathway
HAHTOLA_MYCOSIS_FUNGOIDES_CD4_DN 11671All SZGR genes in this pathway
PUJANA_BRCA1_PCC_NETWORK 16521023All SZGR genes in this pathway
PUJANA_ATM_PCC_NETWORK 1442892All SZGR genes in this pathway
BENPORATH_MYC_MAX_TARGETS 775494All SZGR genes in this pathway
PETRETTO_HEART_MASS_QTL_CIS_UP 2815All SZGR genes in this pathway
BYSTRYKH_HEMATOPOIESIS_STEM_CELL_AND_BRAIN_QTL_TRANS 185114All SZGR genes in this pathway
HADDAD_B_LYMPHOCYTE_PROGENITOR 293193All SZGR genes in this pathway
LU_AGING_BRAIN_DN 153120All SZGR genes in this pathway
BLALOCK_ALZHEIMERS_DISEASE_DN 1237837All SZGR genes in this pathway
LEE_AGING_NEOCORTEX_UP 8959All SZGR genes in this pathway
BLALOCK_ALZHEIMERS_DISEASE_INCIPIENT_DN 165106All SZGR genes in this pathway
BILD_MYC_ONCOGENIC_SIGNATURE 206117All SZGR genes in this pathway
SMID_BREAST_CANCER_NORMAL_LIKE_UP 476285All SZGR genes in this pathway
BLUM_RESPONSE_TO_SALIRASIB_DN 342220All SZGR genes in this pathway
LEE_DIFFERENTIATING_T_LYMPHOCYTE 200115All SZGR genes in this pathway
GUTIERREZ_CHRONIC_LYMPHOCYTIC_LEUKEMIA_DN 5639All SZGR genes in this pathway
DANG_BOUND_BY_MYC 1103714All SZGR genes in this pathway
CHYLA_CBFA2T3_TARGETS_DN 242146All SZGR genes in this pathway
FORTSCHEGGER_PHF8_TARGETS_UP 279155All SZGR genes in this pathway
ZWANG_DOWN_BY_2ND_EGF_PULSE 293119All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-15/16/195/424/497178184m8hsa-miR-15abrainUAGCAGCACAUAAUGGUUUGUG
hsa-miR-16brainUAGCAGCACGUAAAUAUUGGCG
hsa-miR-15bbrainUAGCAGCACAUCAUGGUUUACA
hsa-miR-195SZUAGCAGCACAGAAAUAUUGGC
hsa-miR-424CAGCAGCAAUUCAUGUUUUGAA
hsa-miR-497CAGCAGCACACUGUGGUUUGU
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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