Gene Page

Home
Datasets
Search
Analysis & Tools
Documents
About SZGR
Quick search: (e.g. 207 or AKT)

Association Linkage Expression Literature GO_Annotation Gene Network miRNA Targets

Gene Ranking Integration

Association Linkage Expression Literature GO_Annotation Gene Network miRNA Targets Datasets Gene Ranking

Release Site Map Support Contact us

Gene Page: SYN1

Summary

GeneID

6853

Symbol

SYN1

Synonyms

SYN1a|SYN1b|SYNI

Description

synapsin I

Locus tag

RP1-230G1.2

Gene type

protein-coding

Map location

Xp11.23

Gene in Data Sources

Gene set name

Method of gene set

Evidence

Info

GO_Annotation

Mapping neuro-related keywords to Gene Ontology annotations

Hits with neuro-related keywords: 3

General Gene Expression (microarray) ?

Gene Expression in Brain Regions (new)

Top co-expressed genes in Brain Regions (new)

Gene

Pearson's Correlation

Spearman's Correlation

Top 10 positively co-expressed genes

Top 10 negatively co-expressed genes

Gene Ontology

Molecular function

GO term

Evidence

Neuro keywords

PubMed ID

GO:0003824

catalytic activity

IEA

GO:0003779

actin binding

IEA

GO:0005524

ATP binding

IEA

GO:0005215

transporter activity

TAS

2110562

Biological process

GO term

Evidence

Neuro keywords

PubMed ID

GO:0007269

neurotransmitter secretion

IEA

neuron, axon, Synap, serotonin, Neurotransmitter, dopamine (GO term level: 8)

GO:0007268

synaptic transmission

TAS

neuron, Synap, Neurotransmitter (GO term level: 6)

2110562

Cellular component

GO term

Evidence

Neuro keywords

PubMed ID

GO:0008021

synaptic vesicle

IEA

Synap, Neurotransmitter (GO term level: 12)

GO:0045202

synapse

IEA

neuron, Synap, Neurotransmitter, Glial (GO term level: 2)

GO:0005794

Golgi apparatus

IEA

GO:0005634

nucleus

IDA

18029348

GO:0005737

cytoplasm

IDA

18029348

GO:0030054

cell junction

IEA

Protein-protein Interactions

Shown by network

Interactors	Aliases B	Official full name B	Experimental	Source	PubMed ID
AMPH	AMPH1	amphiphysin	-	HPRD,BioGRID	10899172
BIN1	AMPH2 \| AMPHL \| DKFZp547F068 \| MGC10367 \| SH3P9	bridging integrator 1	-	HPRD,BioGRID	10899172
CRK	CRKII	v-crk sarcoma virus CT10 oncogene homolog (avian)	-	HPRD,BioGRID	10899172
GRB2	ASH \| EGFRBP-GRB2 \| Grb3-3 \| MST084 \| MSTP084	growth factor receptor-bound protein 2	-	HPRD	8022809
GRB2	ASH \| EGFRBP-GRB2 \| Grb3-3 \| MST084 \| MSTP084	growth factor receptor-bound protein 2	-	HPRD,BioGRID	8022809\|10899172
KAT5	ESA1 \| HTATIP \| HTATIP1 \| PLIP \| TIP \| TIP60 \| cPLA2	K(lysine) acetyltransferase 5	Two-hybrid	BioGRID	16169070
NCF1	FLJ79451 \| NCF1A \| NOXO2 \| SH3PXD1A \| p47phox	neutrophil cytosolic factor 1	in vivo	BioGRID	10899172
NCF1C	SH3PXD1C	neutrophil cytosolic factor 1C pseudogene	-	HPRD	10899172
NOS1	IHPS1 \| NOS \| nNOS	nitric oxide synthase 1 (neuronal)	Reconstituted Complex	BioGRID	11867766
NOS1AP	6330408P19Rik \| CAPON \| MGC138500	nitric oxide synthase 1 (neuronal) adaptor protein	-	HPRD,BioGRID	11867766
PFN2	D3S1319E \| PFL	profilin 2	-	HPRD	9463375
PIK3R1	GRB1 \| p85 \| p85-ALPHA	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	-	HPRD,BioGRID	10899172
PLCG1	PLC-II \| PLC1 \| PLC148 \| PLCgamma1	phospholipase C, gamma 1	-	HPRD	10899172
RASA1	CM-AVM \| CMAVM \| DKFZp434N071 \| GAP \| PKWS \| RASA \| RASGAP \| p120GAP \| p120RASGAP	RAS p21 protein activator (GTPase activating protein) 1	-	HPRD,BioGRID	10899172
SH3GL2	CNSA2 \| EEN-B1 \| FLJ20276 \| FLJ25015 \| SH3D2A \| SH3P4	SH3-domain GRB2-like 2	Reconstituted Complex	BioGRID	12456676
SPTAN1	(ALPHA)II-SPECTRIN \| FLJ44613 \| NEAS	spectrin, alpha, non-erythrocytic 1 (alpha-fodrin)	-	HPRD	1905928
SRC	ASV \| SRC1 \| c-SRC \| p60-Src	v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)	-	HPRD,BioGRID	10899172
SYN1	SYN1a \| SYN1b \| SYNI	synapsin I	Two-hybrid	BioGRID	16169070
SYN2	SYNII \| SYNIIa \| SYNIIb	synapsin II	-	HPRD,BioGRID	10358015
SYN3	-	synapsin III	-	HPRD	10358015
VIM	FLJ36605	vimentin	Two-hybrid	BioGRID	16169070

Pathway annotation

Pathway name	Pathway size	# SZGR genes in pathway	Info
REACTOME_TRANSMISSION_ACROSS_CHEMICAL_SYNAPSES	186	155	All SZGR genes in this pathway
REACTOME_NEURONAL_SYSTEM	279	221	All SZGR genes in this pathway
REACTOME_NEUROTRANSMITTER_RELEASE_CYCLE	34	30	All SZGR genes in this pathway
REACTOME_DOPAMINE_NEUROTRANSMITTER_RELEASE_CYCLE	11	11	All SZGR genes in this pathway
KINSEY_TARGETS_OF_EWSR1_FLII_FUSION_UP	1278	748	All SZGR genes in this pathway
LI_AMPLIFIED_IN_LUNG_CANCER	178	108	All SZGR genes in this pathway
SCHAEFFER_PROSTATE_DEVELOPMENT_6HR_DN	514	330	All SZGR genes in this pathway
BLALOCK_ALZHEIMERS_DISEASE_DN	1237	837	All SZGR genes in this pathway
KEEN_RESPONSE_TO_ROSIGLITAZONE_DN	106	68	All SZGR genes in this pathway
HELLER_HDAC_TARGETS_SILENCED_BY_METHYLATION_UP	461	298	All SZGR genes in this pathway
VART_KSHV_INFECTION_ANGIOGENIC_MARKERS_UP	165	118	All SZGR genes in this pathway
HUNSBERGER_EXERCISE_REGULATED_GENES	31	26	All SZGR genes in this pathway
KIM_ALL_DISORDERS_OLIGODENDROCYTE_NUMBER_CORR_UP	756	494	All SZGR genes in this pathway
DURAND_STROMA_S_UP	297	194	All SZGR genes in this pathway

miRNA Targets ?

miRNA family	Target position			miRNA ID	miRNA seq
miRNA family	UTR start	UTR end	Match method	miRNA ID	miRNA seq
miR-153	665	671	1A	hsa-miR-153	UUGCAUAGUCACAAAAGUGA
miR-19	696	703	1A,m8	hsa-miR-19a	UGUGCAAAUCUAUGCAAAACUGA
miR-19	696	703	1A,m8	hsa-miR-19b	UGUGCAAAUCCAUGCAAAACUGA
miR-448	664	671	1A,m8	hsa-miR-448	UUGCAUAUGUAGGAUGUCCCAU
miR-452	667	673	m8	hsa-miR-452	UGUUUGCAGAGGAAACUGAGAC
miR-539	58	65	1A,m8	hsa-miR-539	GGAGAAAUUAUCCUUGGUGUGU

SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.