Gene Page: TEP1

Summary
GeneID  7011
Symbol  TEP1
Synonyms  TLP1|TP1|TROVE1|VAULT2|p240
Description  telomerase-associated protein 1
See related  HGNC:11726|MIM:601686|Ensembl:ENSG00000129566|HPRD:03404|
Locus tag  -
Gene type  protein-coding
Map location  14q11.2
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_Igenome scan meta-analysisPsr: 0.047 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
SYTL10.670.38
FAM70A0.650.44
LRMP0.630.57
SCN11A0.610.24
KLK70.590.61
MATN20.570.55
BAIAP30.570.68
TJP30.550.45
CYP26B10.550.47
SLC38A80.550.52
Top 10 negatively co-expressed genes
CCNI-0.15-0.21
ZNF124-0.15-0.27
IGFBP2-0.15-0.35
KIAA1949-0.15-0.32
BZW2-0.15-0.23
C5orf13-0.14-0.22
ISLR2-0.14-0.20
ZNF695-0.14-0.26
SH3BP2-0.14-0.39
TUBB2B-0.14-0.38
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0000166nucleotide bindingIEA-
GO:0003720telomerase activityIDA12135483 
GO:0003723RNA bindingISS-
GO:0005524ATP bindingIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0000722telomere maintenance via recombinationIDA10810353 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0000781chromosome, telomeric regionIEA-
GO:0005625soluble fractionISS-
GO:0005634nucleusIEA-
GO:0005694chromosomeIEA-
GO:0005697telomerase holoenzyme complexIDA12135483 
GO:0005737cytoplasmIDA7876352 
GO:0016363nuclear matrixIDA7876352 
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
PRKCAAAG6 | MGC129900 | MGC129901 | PKC-alpha | PKCA | PRKACAprotein kinase C, alpha-HPRD9837921 
TERTEST2 | TCS1 | TP2 | TRT | hEST2telomerase reverse transcriptase-HPRD,BioGRID11029039 
TP53FLJ92943 | LFS1 | TRP53 | p53tumor protein p53-HPRD,BioGRID10597287 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
BIOCARTA_TEL_PATHWAY 1815All SZGR genes in this pathway
GAL_LEUKEMIC_STEM_CELL_DN 244153All SZGR genes in this pathway
SHIN_B_CELL_LYMPHOMA_CLUSTER_7 2722All SZGR genes in this pathway
KAUFFMANN_DNA_REPAIR_GENES 230137All SZGR genes in this pathway
KAUFFMANN_DNA_REPLICATION_GENES 14787All SZGR genes in this pathway
SWEET_KRAS_TARGETS_DN 6639All SZGR genes in this pathway
BASSO_B_LYMPHOCYTE_NETWORK 14396All SZGR genes in this pathway
SANSOM_APC_TARGETS_DN 366238All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_48HR_DN 504323All SZGR genes in this pathway
SMID_BREAST_CANCER_NORMAL_LIKE_UP 476285All SZGR genes in this pathway
BHATI_G2M_ARREST_BY_2METHOXYESTRADIOL_UP 12568All SZGR genes in this pathway
CONRAD_STEM_CELL 3927All SZGR genes in this pathway
CHEN_METABOLIC_SYNDROM_NETWORK 1210725All SZGR genes in this pathway
BYSTRYKH_HEMATOPOIESIS_STEM_CELL_SCP2_QTL_TRANS 2513All SZGR genes in this pathway
KATSANOU_ELAVL1_TARGETS_DN 14888All SZGR genes in this pathway


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