|
GeneID |
7051
|
Symbol |
TGM1
|
Synonyms |
ICR2|KTG|LI|LI1|TGASE|TGK
|
Description |
transglutaminase 1 (K polypeptide epidermal type I, protein-glutamine-gamma-glutamyltransferase) |
See related |
HGNC:11777|MIM:190195|Ensembl:ENSG00000092295|HPRD:01824| |
Locus tag |
- |
Gene type |
protein-coding |
Map location |
14q11.2 |
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|
Gene set name |
Method of gene set |
Evidence |
Info |
GSMA_I | genome scan meta-analysis | Psr: 0.047 | |
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General Gene Expression (microarray) ? |
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Gene Expression in Brain Regions (new) |
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Top co-expressed genes in Brain Regions (new) |
|
Gene | Pearson's Correlation | Spearman's Correlation | | |
Top 10 positively co-expressed genes |
FYCO1 | 0.87 | 0.89 | | |
DOCK1 | 0.87 | 0.86 | | |
ARHGEF10 | 0.86 | 0.85 | | |
MYO10 | 0.85 | 0.85 | | |
PHLPP1 | 0.84 | 0.84 | | |
FGFR2 | 0.83 | 0.80 | | |
TJP1 | 0.83 | 0.81 | | |
TNS1 | 0.82 | 0.85 | | |
RRBP1 | 0.82 | 0.84 | | |
SNX33 | 0.81 | 0.84 | | |
Top 10 negatively co-expressed genes | NDUFAF2 | -0.54 | -0.61 | | |
ZNF32 | -0.54 | -0.61 | | |
PFDN5 | -0.53 | -0.61 | | |
VPS29 | -0.52 | -0.57 | | |
PSMA6 | -0.52 | -0.60 | | |
ST20 | -0.52 | -0.61 | | |
PPP2R3C | -0.51 | -0.57 | | |
COMMD3 | -0.51 | -0.56 | | |
PFDN4 | -0.51 | -0.62 | | |
GTF3A | -0.51 | -0.57 | | |
|
Molecular function | GO term | Evidence | Neuro keywords | PubMed ID |
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GO:0003810 | protein-glutamine gamma-glutamyltransferase activity | IDA | | 7961731 |
GO:0005509 | calcium ion binding | IEA | | - |
GO:0005515 | protein binding | IPI | | 7592852 |9722562 |10066784 |10510474 |
GO:0016740 | transferase activity | IEA | | - |
GO:0008415 | acyltransferase activity | IEA | | - |
Biological process | GO term | Evidence | Neuro keywords | PubMed ID |
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GO:0006464 | protein modification process | NAS | | 1979171 |
GO:0009887 | organ morphogenesis | IEA | | - |
GO:0018149 | peptide cross-linking | IEA | | - |
GO:0030216 | keratinocyte differentiation | IDA | | 8824274 |
GO:0031424 | keratinization | IEA | | - |
GO:0043163 | cell envelope organization | TAS | | 14645372 |
Cellular component | GO term | Evidence | Neuro keywords | PubMed ID |
---|
GO:0001533 | cornified envelope | TAS | | 8824274 |
GO:0016020 | membrane | IEA | | - |
GO:0005913 | cell-cell adherens junction | IEA | | - |
GO:0031224 | intrinsic to membrane | IDA | | 8824274 |
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