Gene Page: TIMP4

Summary
GeneID  7079
Symbol  TIMP4
Synonyms  -
Description  TIMP metallopeptidase inhibitor 4
See related  HGNC:11823|MIM:601915|Ensembl:ENSG00000157150|HPRD:03557|
Locus tag  -
Gene type  protein-coding
Map location  3p25
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_Igenome scan meta-analysisPsr: 0.006 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
ICAM20.840.69
TMEM2040.790.67
GIMAP50.780.61
C10orf100.780.49
IL320.770.54
SH3TC10.740.53
CDC42EP50.700.72
HRCT10.700.32
GGT50.700.56
RRAS0.680.59
Top 10 negatively co-expressed genes
GGNBP2-0.56-0.57
DNAJC7-0.55-0.53
DNM1L-0.54-0.53
AC141586.1-0.53-0.56
SLC4A1AP-0.53-0.49
TAOK3-0.53-0.51
MPHOSPH8-0.53-0.57
DDX42-0.53-0.51
RP11-298P3.1-0.52-0.55
SDCCAG1-0.52-0.56
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005515protein bindingIEA-
GO:0004857enzyme inhibitor activityIEA-
GO:0008191metalloendopeptidase inhibitor activityNAS8939999 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0008150biological_processND-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005576extracellular regionNAS-
GO:0005578proteinaceous extracellular matrixIEA-
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
MMP2CLG4 | CLG4A | MMP-II | MONA | TBE-1matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)-HPRD,BioGRID9182583 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
DODD_NASOPHARYNGEAL_CARCINOMA_UP 1821933All SZGR genes in this pathway
MCBRYAN_PUBERTAL_BREAST_3_4WK_DN 3927All SZGR genes in this pathway
GOUYER_TATI_TARGETS_DN 1712All SZGR genes in this pathway
WOTTON_RUNX_TARGETS_UP 2114All SZGR genes in this pathway
BENPORATH_NANOG_TARGETS 988594All SZGR genes in this pathway
BENPORATH_SOX2_TARGETS 734436All SZGR genes in this pathway
CHEN_LVAD_SUPPORT_OF_FAILING_HEART_UP 10369All SZGR genes in this pathway
SAGIV_CD24_TARGETS_DN 4626All SZGR genes in this pathway
SMID_BREAST_CANCER_RELAPSE_IN_BONE_UP 9761All SZGR genes in this pathway
SMID_BREAST_CANCER_RELAPSE_IN_LUNG_DN 3722All SZGR genes in this pathway
SMID_BREAST_CANCER_LUMINAL_A_UP 8452All SZGR genes in this pathway
SMID_BREAST_CANCER_BASAL_DN 701446All SZGR genes in this pathway
BASSO_HAIRY_CELL_LEUKEMIA_DN 8066All SZGR genes in this pathway
ZHENG_GLIOBLASTOMA_PLASTICITY_UP 250168All SZGR genes in this pathway
BOQUEST_STEM_CELL_CULTURED_VS_FRESH_UP 425298All SZGR genes in this pathway
BHATI_G2M_ARREST_BY_2METHOXYESTRADIOL_DN 12775All SZGR genes in this pathway
RUIZ_TNC_TARGETS_UP 153107All SZGR genes in this pathway
LIU_VAV3_PROSTATE_CARCINOGENESIS_UP 8961All SZGR genes in this pathway
MIKKELSEN_IPS_LCP_WITH_H3K4ME3 174100All SZGR genes in this pathway
NAKAYAMA_SOFT_TISSUE_TUMORS_PCA2_DN 8051All SZGR genes in this pathway
MIKKELSEN_ES_LCP_WITH_H3K4ME3 14280All SZGR genes in this pathway
MIKKELSEN_NPC_LCP_WITH_H3K4ME3 5834All SZGR genes in this pathway
NAKAMURA_ADIPOGENESIS_LATE_UP 10467All SZGR genes in this pathway
MARTENS_TRETINOIN_RESPONSE_UP 857456All SZGR genes in this pathway
BRUINS_UVC_RESPONSE_VIA_TP53_GROUP_B 549316All SZGR genes in this pathway
RAO_BOUND_BY_SALL4_ISOFORM_B 517302All SZGR genes in this pathway
ACEVEDO_FGFR1_TARGETS_IN_PROSTATE_CANCER_MODEL_DN 308187All SZGR genes in this pathway
NABA_ECM_REGULATORS 238125All SZGR genes in this pathway
NABA_MATRISOME_ASSOCIATED 753411All SZGR genes in this pathway
NABA_MATRISOME 1028559All SZGR genes in this pathway


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