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Association Linkage Expression Literature GO_Annotation Gene Network miRNA Targets

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Association Linkage Expression Literature GO_Annotation Gene Network miRNA Targets Datasets Gene Ranking

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Gene Page: TNFRSF1B

Summary

GeneID

7133

Symbol

TNFRSF1B

Synonyms

Description

tumor necrosis factor receptor superfamily, member 1B

Locus tag

Gene type

protein-coding

Map location

1p36.3-p36.2

Gene in Data Sources

Gene set name

Method of gene set

Evidence

Info

Literature

High-throughput literature-search

Co-occurance with Schizophrenia keywords: [schizophrenia, schizophrenias]

Click to show detail

Network

Shortest path distance of core genes in the Human protein-protein interaction network

Contribution to shortest path in PPI network: 0.0593

General Gene Expression (microarray) ?

Gene Expression in Brain Regions (new)

Top co-expressed genes in Brain Regions (new)

Gene

Pearson's Correlation

Spearman's Correlation

Top 10 positively co-expressed genes

Top 10 negatively co-expressed genes

Gene Ontology

Molecular function

GO term

Evidence

Neuro keywords

PubMed ID

GO:0004872

receptor activity

IEA

GO:0005031

tumor necrosis factor receptor activity

TAS

8702885

GO:0005515

protein binding

IEA

GO:0005515

protein binding

IPI

11244088

Biological process

GO term

Evidence

Neuro keywords

PubMed ID

GO:0008219

cell death

IEA

GO:0007166

cell surface receptor linked signal transduction

IEA

GO:0006915

apoptosis

IEA

GO:0050728

negative regulation of inflammatory response

IEA

GO:0050779

RNA destabilization

IEA

Cellular component

GO term

Evidence

Neuro keywords

PubMed ID

GO:0005576

extracellular region

IEA

GO:0005634

nucleus

IDA

18029348

GO:0005730

nucleolus

IDA

18029348

GO:0005737

cytoplasm

IDA

18029348

GO:0016020

membrane

IEA

GO:0016021

integral to membrane

IEA

GO:0005886

plasma membrane

IEA

Protein-protein Interactions

Shown by network

Interactors	Aliases B	Official full name B	Experimental	Source	PubMed ID
AIFM1	AIF \| MGC111425 \| PDCD8	apoptosis-inducing factor, mitochondrion-associated, 1	-	HPRD	14743216
ATAD3A	FLJ10709	ATPase family, AAA domain containing 3A	-	HPRD	14743216
ATP1A1	MGC3285 \| MGC51750	ATPase, Na+/K+ transporting, alpha 1 polypeptide	-	HPRD	14743216
ATP2A1	ATP2A \| SERCA1	ATPase, Ca++ transporting, cardiac muscle, fast twitch 1	-	HPRD	14743216
ATP2A2	ATP2B \| DAR \| DD \| DKFZp686P0211 \| FLJ20293 \| FLJ38063 \| MGC45367 \| SERCA2	ATPase, Ca++ transporting, cardiac muscle, slow twitch 2	-	HPRD	14743216
ATP5A1	ATP5A \| ATP5AL2 \| ATPM \| MOM2 \| OMR \| ORM \| hATP1	ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle	-	HPRD	14743216
CAV1	CAV \| MSTP085 \| VIP21	caveolin 1, caveolae protein, 22kDa	-	HPRD,BioGRID	11112773
CBWD2	-	COBW domain containing 2	-	HPRD	14743216
CDIPT	MGC1328 \| PIS \| PIS1	CDP-diacylglycerol--inositol 3-phosphatidyltransferase (phosphatidylinositol synthase)	-	HPRD	14743216
CSE1L	CAS \| CSE1 \| MGC117283 \| MGC130036 \| MGC130037 \| XPO2	CSE1 chromosome segregation 1-like (yeast)	-	HPRD	14743216
CSNK1A1	CK1 \| HLCDGP1 \| PRO2975	casein kinase 1, alpha 1	-	HPRD,BioGRID	7559483
DDB1	DDBA \| UV-DDB1 \| XAP1 \| XPCE \| XPE \| XPE-BF	damage-specific DNA binding protein 1, 127kDa	-	HPRD	14743216
FANCD2	DKFZp762A223 \| FA-D2 \| FA4 \| FACD \| FAD \| FAD2 \| FANCD \| FLJ23826	Fanconi anemia, complementation group D2	Affinity Capture-MS	BioGRID	14743216
FANCI	FLJ10719 \| KIAA1794	Fanconi anemia, complementation group I	-	HPRD	14743216
GCN1L1	GCN1 \| GCN1L \| KIAA0219	GCN1 general control of amino-acid synthesis 1-like 1 (yeast)	-	HPRD	14743216
HAX1	FLJ17042 \| FLJ18492 \| FLJ93803 \| HCLSBP1 \| HS1BP1 \| SCN3	HCLS1 associated protein X-1	-	HPRD	14743216
HEATR6	ABC1 \| DKFZp686D22141 \| FLJ22087 \| MGC148096	HEAT repeat containing 6	-	HPRD	14743216
HIVEP3	FLJ16752 \| KBP-1 \| KBP1 \| KIAA1555 \| KRC \| SHN3 \| Schnurri-3 \| ZAS3 \| ZNF40C	human immunodeficiency virus type I enhancer binding protein 3	-	HPRD	11804591
HSPA8	HSC54 \| HSC70 \| HSC71 \| HSP71 \| HSP73 \| HSPA10 \| LAP1 \| MGC131511 \| MGC29929 \| NIP71	heat shock 70kDa protein 8	-	HPRD	14743216
KCTD12	C13orf2 \| FLJ33073 \| KIAA1778 \| PFET1 \| PFETIN	potassium channel tetramerisation domain containing 12	-	HPRD	14743216
KRT18	CYK18 \| K18	keratin 18	-	HPRD,BioGRID	10747083
LTA	LT \| TNFB \| TNFSF1	lymphotoxin alpha (TNF superfamily, member 1)	-	HPRD,BioGRID	2160731 \|8123048\|9552007
MON2	KIAA1040 \| MGC35493	MON2 homolog (S. cerevisiae)	-	HPRD	14743216
PTPLAD1	B-IND1 \| FLJ90376 \| HSPC121	protein tyrosine phosphatase-like A domain containing 1	-	HPRD	14743216
RPL38	-	ribosomal protein L38	-	HPRD	14743216
RPS27L	-	ribosomal protein S27-like	-	HPRD	14743216
RPS3	FLJ26283 \| FLJ27450 \| MGC87870	ribosomal protein S3	-	HPRD	14743216
SEC61A1	HSEC61 \| SEC61 \| SEC61A	Sec61 alpha 1 subunit (S. cerevisiae)	-	HPRD	14743216
STAT1	DKFZp686B04100 \| ISGF-3 \| STAT91	signal transducer and activator of transcription 1, 91kDa	-	HPRD	10848577
TNF	DIF \| TNF-alpha \| TNFA \| TNFSF2	tumor necrosis factor (TNF superfamily, member 2)	Affinity Capture-MS	BioGRID	14743216
			-	HPRD	8590321 \|9552007
			TNF-alpha interacts with TNFR-2.	BIND	7852363
TNFRSF1B	CD120b \| TBPII \| TNF-R-II \| TNF-R75 \| TNFBR \| TNFR1B \| TNFR2 \| TNFR80 \| p75 \| p75TNFR	tumor necrosis factor receptor superfamily, member 1B	Affinity Capture-Western FRET	BioGRID	10875917
TRAF1	EBI6 \| MGC:10353	TNF receptor-associated factor 1	-	HPRD	8069916
TRAF1	EBI6 \| MGC:10353	TNF receptor-associated factor 1	Reconstituted Complex	BioGRID	9162022
TRAF2	MGC:45012 \| TRAP \| TRAP3	TNF receptor-associated factor 2	TRAF2 interacts with TRAF1. This interaction was modeled on a demonstrated interaction between human TRAF2 and TNF-R2 from an unspecified species.	BIND	8702708
			-	HPRD	7639698 \|8702708 \|9461607 \|11907088
			Affinity Capture-MS Affinity Capture-Western Reconstituted Complex Two-hybrid	BioGRID	7639698 \|8702708 \|8710854 \|9162022 \|11907088 \|14743216
TRAIP	RNF206 \| TRIP	TRAF interacting protein	-	HPRD,BioGRID	9104814
TTRAP	AD022 \| EAP2 \| MGC111021 \| MGC9099 \| dJ30M3.3	TRAF and TNF receptor associated protein	-	HPRD,BioGRID	10764746
TUBA3C	TUBA2 \| bA408E5.3	tubulin, alpha 3c	-	HPRD	14743216
TUBB2B	DKFZp566F223 \| FLJ98847 \| MGC8685 \| TUBB-PARALOG \| bA506K6.1	tubulin, beta 2B	-	HPRD	14743216
XPNPEP3	APP3	X-prolyl aminopeptidase (aminopeptidase P) 3, putative	-	HPRD	14743216

miRNA Targets ?

miRNA family	Target position			miRNA ID	miRNA seq
miRNA family	UTR start	UTR end	Match method	miRNA ID	miRNA seq
let-7/98	1261	1268	1A,m8	hsa-let-7a^brain	UGAGGUAGUAGGUUGUAUAGUU
				hsa-let-7b^brain	UGAGGUAGUAGGUUGUGUGGUU
				hsa-let-7c^brain	UGAGGUAGUAGGUUGUAUGGUU
				hsa-let-7d^brain	AGAGGUAGUAGGUUGCAUAGU
				hsa-let-7e^brain	UGAGGUAGGAGGUUGUAUAGU
				hsa-let-7f^brain	UGAGGUAGUAGAUUGUAUAGUU
				hsa-miR-98^brain	UGAGGUAGUAAGUUGUAUUGUU
				hsa-let-7g^SZ	UGAGGUAGUAGUUUGUACAGU
				hsa-let-7i^brain	UGAGGUAGUAGUUUGUGCUGU

SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.