Gene Page: TNP1

Summary
GeneID  7141
Symbol  TNP1
Synonyms  TP1
Description  transition protein 1 (during histone to protamine replacement)
See related  HGNC:11951|MIM:190231|Ensembl:ENSG00000118245|HPRD:01830|
Locus tag  -
Gene type  protein-coding
Map location  2q35-q36
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_IIAgenome scan meta-analysis (All samples)Psr: 0.00916 
GSMA_IIEgenome scan meta-analysis (European-ancestry samples)Psr: 0.01016 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
HSPA50.880.91
HSPA90.870.88
PDIA30.870.85
USO10.860.86
CANX0.850.84
CHORDC10.840.85
XPOT0.830.82
RAB5A0.830.84
SYAP10.820.82
DLD0.820.84
Top 10 negatively co-expressed genes
AF347015.21-0.61-0.44
MT-CO2-0.54-0.47
AF347015.31-0.53-0.48
ENHO-0.53-0.52
HIGD1B-0.53-0.45
FXYD1-0.52-0.44
IFI27-0.51-0.45
AF347015.8-0.51-0.44
AF347015.33-0.51-0.44
AF347015.2-0.51-0.45
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0003677DNA bindingIMP12743712 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0000012single strand break repairIDA12743712 
GO:0006337nucleosome disassemblyIMP10781074 
GO:0006338chromatin remodelingIDA12743712 
GO:0006342chromatin silencingIEP11315969 
GO:0007290spermatid nucleus elongationIMP10781074 
GO:0007283spermatogenesisIEA-
GO:0019953sexual reproductionIMP10781074 
GO:0007275multicellular organismal developmentIEA-
GO:0030154cell differentiationIEA-
GO:0035042fertilization, exchange of chromosomal proteinsTAS12743712 
GO:0030317sperm motilityIMP10781074 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0000786nucleosomeIDA12743712 
GO:0005634nucleusIEA-
GO:0005694chromosomeIEA-
 
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-1431821881Ahsa-miR-143brainUGAGAUGAAGCACUGUAGCUCA
miR-1811531591Ahsa-miR-181abrainAACAUUCAACGCUGUCGGUGAGU
hsa-miR-181bSZAACAUUCAUUGCUGUCGGUGGG
hsa-miR-181cbrainAACAUUCAACCUGUCGGUGAGU
hsa-miR-181dbrainAACAUUCAUUGUUGUCGGUGGGUU
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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