Gene Page: C1S

Summary
GeneID  716
Symbol  C1S
Synonyms  FLJ44757
Description  complement component 1, s subcomponent
See related  HGNC:1247|MIM:120580|Ensembl:ENSG00000182326|HPRD:00397|
Locus tag  -
Gene type  protein-coding
Map location  12p13
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 1 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
STK19P0.820.57
ITGB40.710.49
CD440.650.43
AC015908.20.650.38
GFAP0.640.39
APLNR0.640.39
GMPR0.610.41
MATN20.610.49
C9orf610.610.46
FAM188B0.600.40
Top 10 negatively co-expressed genes
ARL4D-0.22-0.12
IER5L-0.22-0.14
EMX1-0.19-0.17
KHDRBS3-0.19-0.08
BZW2-0.19-0.10
GPR21-0.19-0.07
NEUROD6-0.19-0.09
SRPK1-0.18-0.05
DPP4-0.18-0.08
C1orf96-0.18-0.06
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0004252serine-type endopeptidase activityTASglutamate (GO term level: 7)9856483 
GO:0005509calcium ion bindingIEA-
GO:0008233peptidase activityIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006508proteolysisIEA-
GO:0006958complement activation, classical pathwayIEA-
GO:0045087innate immune responseIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005576extracellular regionEXP814163 |1249422 
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
C1QA-complement component 1, q subcomponent, A chain-HPRD,BioGRID10878362 
C1R-complement component 1, r subcomponent-HPRD2372546|9477945 |10092586 
Affinity Capture-Western
in vitro
Reconstituted Complex
BioGRID9477945 |10092586 
|10878362 
SERPING1C1IN | C1INH | C1NH | HAE1 | HAE2serpin peptidase inhibitor, clade G (C1 inhibitor), member 1-HPRD,BioGRID6604523|9882449 
 


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