Gene Page: TRAF2

Summary
GeneID  7186
Symbol  TRAF2
Synonyms  MGC:45012|TRAP|TRAP3
Description  TNF receptor-associated factor 2
See related  HGNC:12032|MIM:601895|Ensembl:ENSG00000127191|HPRD:03538|
Locus tag  -
Gene type  protein-coding
Map location  9q34
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
NetworkShortest path distance of core genes in the Human protein-protein interaction networkContribution to shortest path in PPI network: 0.2666 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
Top 10 negatively co-expressed genes
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0004871signal transducer activityNAS8702708 
GO:0005515protein bindingIPI11466612 |11777919 
GO:0008270zinc ion bindingIEA-
GO:0046872metal ion bindingIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0002726positive regulation of T cell cytokine productionIMP15125833 
GO:0006461protein complex assemblyTAS8702708 
GO:0007250activation of NF-kappaB-inducing kinase activityIMP15125833 
GO:0007165signal transductionTAS8702708 
GO:0008633activation of pro-apoptotic gene productsEXP14644197 
GO:0042981regulation of apoptosisIEA-
GO:0050870positive regulation of T cell activationIC15125833 
GO:0032743positive regulation of interleukin-2 productionIMP15125833 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005829cytosolEXP7758105 |12887920 
GO:0005737cytoplasmIEA-
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
AASDHPPTAASD-PPT | CGI-80 | DKFZp566E2346 | LYS2 | LYS5aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferaseTwo-hybridBioGRID16189514 
ABLIM1ABLIM | DKFZp781D0148 | FLJ14564 | KIAA0059 | LIMAB1 | LIMATIN | MGC1224actin binding LIM protein 1Two-hybridBioGRID16189514 
AFF4AF5Q31 | MCEF | MGC75036AF4/FMR2 family, member 4Two-hybridBioGRID16189514 
ANKRD26L1MGC12538ankyrin repeat domain 26-like 1Two-hybridBioGRID16189514 
APEX2APE2 | APEXL2 | XTH2APEX nuclease (apurinic/apyrimidinic endonuclease) 2Two-hybridBioGRID16189514 
APIPAPIP2 | CGI-29 | MMRP19 | dJ179L10.2APAF1 interacting protein-HPRD14743216 
APPL1APPL | DIP13alphaadaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1Two-hybridBioGRID16189514 
BAHD1KIAA0945bromo adjacent homology domain containing 1Two-hybridBioGRID16189514 
BANPBEND1 | DKFZp761H172 | FLJ10177 | FLJ20538 | SMAR1 | SMARBP1BTG3 associated nuclear proteinTwo-hybridBioGRID16189514 
BCL10CARMEN | CIPER | CLAP | c-E10 | mE10B-cell CLL/lymphoma 10-HPRD,BioGRID10753917 
BIRC2API1 | HIAP2 | Hiap-2 | MIHB | RNF48 | cIAP1baculoviral IAP repeat-containing 2c-IAP1 interacts with and ubiquitinates TRAF2.BIND11907583 
-HPRD8643514 |9384571 
|11907583 
Affinity Capture-Western
in vitro
Reconstituted Complex
Two-hybrid
BioGRID8643514 |8943045 
|9384571 |11907583 
|16189514 
BIRC3AIP1 | API2 | CIAP2 | HAIP1 | HIAP1 | MALT2 | MIHC | RNF49baculoviral IAP repeat-containing 3-HPRD8643514 |11907583 
in vitro
Reconstituted Complex
Two-hybrid
BioGRID8643514 |9384571 
|11907583 
c-IAP2 interacts with TRAF2.BIND11907583 
C16orf48DAKV6410 | DKFZp434A1319chromosome 16 open reading frame 48Two-hybridBioGRID16189514 
CALCOCO2MGC17318 | NDP52calcium binding and coiled-coil domain 2Two-hybridBioGRID16189514 
CASP12CASP12P1caspase 12 (gene/pseudogene)Affinity Capture-WesternBioGRID11278723 
CASP8ALPS2B | CAP4 | FLICE | FLJ17672 | MACH | MCH5 | MGC78473caspase 8, apoptosis-related cysteine peptidaseAffinity Capture-WesternBioGRID12887920 
CASP8AP2CED-4 | FLASH | FLJ11208 | KIAA1315 | RIP25caspase 8 associated protein 2-HPRD,BioGRID11340079 
CAV1CAV | MSTP085 | VIP21caveolin 1, caveolae protein, 22kDa-HPRD,BioGRID11112773 |11805080 
CCDC130MGC10471coiled-coil domain containing 130Two-hybridBioGRID16189514 
CCDC33FLJ23168 | FLJ32855 | MGC34145coiled-coil domain containing 33Two-hybridBioGRID16189514 
CD27MGC20393 | S152 | T14 | TNFRSF7 | Tp55CD27 molecule-HPRD,BioGRID9582383 
CD40Bp50 | CDW40 | MGC9013 | TNFRSF5 | p50CD40 molecule, TNF receptor superfamily member 5-HPRD,BioGRID10411888 
CD40 interacts with TRAF2.BIND10352240 
CDCA3GRCC8 | MGC2577 | TOME-1cell division cycle associated 3Two-hybridBioGRID16189514 
CDKN1BCDKN4 | KIP1 | MEN1B | MEN4 | P27KIP1cyclin-dependent kinase inhibitor 1B (p27, Kip1)Two-hybridBioGRID16189514 
CFLARCASH | CASP8AP1 | CLARP | Casper | FLAME | FLAME-1 | FLAME1 | FLIP | I-FLICE | MRIT | c-FLIP | c-FLIPL | c-FLIPR | c-FLIPSCASP8 and FADD-like apoptosis regulator-HPRD,BioGRID9208847 
CHMP2BCHMP2.5 | DKFZp564O123 | DMT1 | VPS2-2 | VPS2Bchromatin modifying protein 2BTwo-hybridBioGRID16189514 
CHUKIKBKA | IKK-alpha | IKK1 | IKKA | NFKBIKA | TCF16conserved helix-loop-helix ubiquitous kinase-HPRD,BioGRID11359906 
CRY1PHLL1cryptochrome 1 (photolyase-like)Two-hybridBioGRID16189514 
CYLDCDMT | CYLD1 | CYLDI | EAC | FLJ20180 | FLJ31664 | FLJ78684 | HSPC057 | KIAA0849 | MFT | MFT1 | SBS | TEM | USPL2cylindromatosis (turban tumor syndrome)CYLD interacts with TRAF2.BIND12917691 
DLGAP5DLG1 | DLG7 | HURP | KIAA0008discs, large (Drosophila) homolog-associated protein 5Two-hybridBioGRID16189514 
DTNBMGC17163 | MGC57126dystrobrevin, betaTwo-hybridBioGRID16189514 
DVL2-dishevelled, dsh homolog 2 (Drosophila)Two-hybridBioGRID16189514 
EDARADDED3 | EDA3EDAR-associated death domainAffinity Capture-WesternBioGRID11882293 
ERN1FLJ30999 | IRE1 | IRE1P | MGC163277 | MGC163279endoplasmic reticulum to nucleus signaling 1-HPRD,BioGRID10650002 |12843613 
FAM107ADRR1 | FLJ30158 | FLJ45473 | TU3Afamily with sequence similarity 107, member ATwo-hybridBioGRID16189514 
FAM120BCCPG | FLJ55614 | KIAA0183 | KIAA1838 | PGCC1 | dJ894D12.1family with sequence similarity 120BTwo-hybridBioGRID16189514 
FATE1FATEfetal and adult testis expressed 1Two-hybridBioGRID16189514 
FBF1Alb | FBF-1 | FLJ00103Fas (TNFRSF6) binding factor 1Two-hybridBioGRID16189514 
FBXO28FLJ10766 | Fbx28 | KIAA0483F-box protein 28Two-hybridBioGRID16189514 
FLNAABP-280 | ABPX | DKFZp434P031 | FLN | FLN1 | FMD | MNS | NHBP | OPD | OPD1 | OPD2filamin A, alpha (actin binding protein 280)-HPRD,BioGRID10617615 
FXR2FMR1L2fragile X mental retardation, autosomal homolog 2Two-hybridBioGRID16189514 
GORASP2DKFZp434D156 | FLJ13139 | GOLPH6 | GRASP55 | GRS2 | p59golgi reassembly stacking protein 2, 55kDaTwo-hybridBioGRID16189514 
HIVEP3FLJ16752 | KBP-1 | KBP1 | KIAA1555 | KRC | SHN3 | Schnurri-3 | ZAS3 | ZNF40Chuman immunodeficiency virus type I enhancer binding protein 3-HPRD,BioGRID11804591 
HSPA4APG-2 | HS24/P52 | MGC131852 | RY | hsp70 | hsp70RYheat shock 70kDa protein 4-HPRD14743216 
HSPA8HSC54 | HSC70 | HSC71 | HSP71 | HSP73 | HSPA10 | LAP1 | MGC131511 | MGC29929 | NIP71heat shock 70kDa protein 8-HPRD14743216 
IKBKBFLJ40509 | IKK-beta | IKK2 | IKKB | MGC131801 | NFKBIKBinhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta-HPRD,BioGRID11359906 
IL15RAMGC104179interleukin 15 receptor, alpha-HPRD,BioGRID11064452 
IPO11RanBP11importin 11Two-hybridBioGRID16189514 
IRF4LSIRF | MUM1interferon regulatory factor 4Two-hybridBioGRID16189514 
ITPK1ITRPK1inositol 1,3,4-triphosphate 5/6 kinaseTwo-hybridBioGRID16189514 
KIAA0408FLJ43995 | RP3-403A15.2KIAA0408Two-hybridBioGRID16189514 
KIAA1267DKFZp686P06109 | DKFZp727C091 | MGC102843KIAA1267Two-hybridBioGRID16189514 
LNX1LNX | MPDZ | PDZRN2ligand of numb-protein X 1Two-hybridBioGRID16189514 
LOC116349-hypothetical protein BC014011Two-hybridBioGRID16189514 
LOC170082MGC17403TFIIS central domain-containing protein 1Two-hybridBioGRID16189514 
LTBRCD18 | D12S370 | LT-BETA-R | TNF-R-III | TNFCR | TNFR-RP | TNFR2-RP | TNFRSF3lymphotoxin beta receptor (TNFR superfamily, member 3)-HPRD12169272 
TRAF2 interacts with LTBR.BIND12571250 
Reconstituted ComplexBioGRID9162022 
LZTS2KIAA1813 | LAPSER1leucine zipper, putative tumor suppressor 2Two-hybridBioGRID16189514 
MALT1DKFZp434L132 | MLT | MLT1mucosa associated lymphoid tissue lymphoma translocation gene 1TRAF2 interacts with MALT1.BIND15125833 
MAP3K1MAPKKK1 | MEKK | MEKK1mitogen-activated protein kinase kinase kinase 1Affinity Capture-Western
Co-fractionation
BioGRID10346818 
MAP3K14FTDCR1B | HS | HSNIK | NIKmitogen-activated protein kinase kinase kinase 14-HPRD,BioGRID9020361 |11278268 
NIK interacts with TRAF2. This interaction was modeled on a demonstrated interaction between human NIK and TRAF2 from an unspecified species.BIND9275204 
MAP3K5ASK1 | MAPKKK5 | MEKK5mitogen-activated protein kinase kinase kinase 5-HPRD,BioGRID9774977 |10523862 
MAP3K7TAK1 | TGF1amitogen-activated protein kinase kinase kinase 7Affinity Capture-WesternBioGRID14633987 
-HPRD14743216 
MAP3K7IP13'-Tab1 | MGC57664 | TAB1mitogen-activated protein kinase kinase kinase 7 interacting protein 1Affinity Capture-MSBioGRID14743216 
MAP3K7IP3MGC45404 | NAP1 | TAB3mitogen-activated protein kinase kinase kinase 7 interacting protein 3-HPRD,BioGRID14633987 
MAP3K8COT | EST | ESTF | FLJ10486 | TPL2 | Tpl-2 | c-COTmitogen-activated protein kinase kinase kinase 8-HPRD,BioGRID11932422 
MAP4K2BL44 | GCK | RAB8IPmitogen-activated protein kinase kinase kinase kinase 2-HPRD,BioGRID9712898 
The carboxy-terminal TRAF domain of TRAF2 interacts with the carboxy-terminal domain of GCK.BIND9712898 
MAP4K5GCKR | KHS | KHS1 | MAPKKKK5mitogen-activated protein kinase kinase kinase kinase 5-HPRD,BioGRID10477597 
MAPK9JNK-55 | JNK2 | JNK2A | JNK2ALPHA | JNK2B | JNK2BETA | PRKM9 | SAPK | p54a | p54aSAPKmitogen-activated protein kinase 9-HPRD10490605 
MAST2FLJ39200 | KIAA0807 | MAST205 | MTSSK | RP4-533D7.1microtubule associated serine/threonine kinase 2Affinity Capture-WesternBioGRID15308666 
MIZFDKFZp434F162 | HiNF-P | ZNF743MBD2-interacting zinc fingerTwo-hybridBioGRID16189514 
NECAP2FLJ10420 | RP4-798A10.1NECAP endocytosis associated 2Two-hybridBioGRID16189514 
NGFRCD271 | Gp80-LNGFR | TNFRSF16 | p75(NTR) | p75NTRnerve growth factor receptor (TNFR superfamily, member 16)-HPRD,BioGRID10514511 
NGFRAP1BEX3 | Bex | DXS6984E | HGR74 | NADEnerve growth factor receptor (TNFRSF16) associated protein 1-HPRD10514511 
NIF3L1ALS2CR1 | CALS-7 | MDS015NIF3 NGG1 interacting factor 3-like 1 (S. pombe)Two-hybridBioGRID16189514 
NRIP1FLJ77253 | RIP140nuclear receptor interacting protein 1Two-hybridBioGRID16189514 
NUDT18FLJ22494nudix (nucleoside diphosphate linked moiety X)-type motif 18Two-hybridBioGRID16189514 
PIN1DOD | UBL5peptidylprolyl cis/trans isomerase, NIMA-interacting 1Two-hybridBioGRID16189514 
PSMF1PI31proteasome (prosome, macropain) inhibitor subunit 1 (PI31)Two-hybridBioGRID16189514 
PTPN2PTPT | TC-PTP | TCELLPTP | TCPTPprotein tyrosine phosphatase, non-receptor type 2PTPN2 (TCPTP) interacts with TRAF2.BIND15696169 
QARSGLNRS | PRO2195glutaminyl-tRNA synthetaseTwo-hybridBioGRID16189514 
RAD23AHHR23A | MGC111083RAD23 homolog A (S. cerevisiae)Two-hybridBioGRID16189514 
RB1CC1CC1 | DRAGOU14 | FIP200RB1-inducible coiled-coil 1Affinity Capture-WesternBioGRID17015619 
RFX3MGC87155 | bA32F11.1regulatory factor X, 3 (influences HLA class II expression)Two-hybridBioGRID16189514 
RGS14-regulator of G-protein signaling 14Two-hybridBioGRID16189514 
RIBC2C22orf11RIB43A domain with coiled-coils 2Two-hybridBioGRID16189514 
RIPK1FLJ39204 | RIP | RIP1receptor (TNFRSF)-interacting serine-threonine kinase 1-HPRD,BioGRID8612133 |8702708 
TRAF2 ubiquitinates RIP.BIND15258597 
TRAF2 interacts with RIP.BIND8702708 
RIPK2CARD3 | CARDIAK | CCK | GIG30 | RICK | RIP2receptor-interacting serine-threonine kinase 2-HPRD,BioGRID9705938 
RIPK3RIP3receptor-interacting serine-threonine kinase 3-HPRD,BioGRID10339433 
RUVBL2CGI-46 | ECP51 | INO80J | REPTIN | RVB2 | TIH2 | TIP48 | TIP49BRuvB-like 2 (E. coli)-HPRD14743216 
SETD5DKFZp686J18276 | FLJ10707 | KIAA1757SET domain containing 5Two-hybridBioGRID16189514 
SIAH2hSiah2seven in absentia homolog 2 (Drosophila)-HPRD,BioGRID12411493 
SOX30-SRY (sex determining region Y)-box 30Two-hybridBioGRID16189514 
SOX9CMD1 | CMPD1 | SRA1SRY (sex determining region Y)-box 9-HPRD12136106 
SPATA2FLJ13167 | KIAA0757 | PD1 | tamospermatogenesis associated 2Two-hybridBioGRID16189514 
SPG21ACP33 | BM-019 | GL010 | MASPARDIN | MASTspastic paraplegia 21 (autosomal recessive, Mast syndrome)Two-hybridBioGRID16189514 
SPHK1SPHKsphingosine kinase 1-HPRD,BioGRID11777919 
SPRY2MGC23039 | hSPRY2sprouty homolog 2 (Drosophila)Two-hybridBioGRID16189514 
TANKI-TRAF | TRAF2TRAF family member-associated NFKB activator-HPRD,BioGRID8710854 |10581243 
TAOK3DKFZp666H245 | DPK | FLJ31808 | JIK | MAP3K18TAO kinase 3-HPRD,BioGRID11278723 
TBK1FLJ11330 | NAK | T2KTANK-binding kinase 1-HPRD,BioGRID10990461 
TCEA2TFIIStranscription elongation factor A (SII), 2Two-hybridBioGRID16189514 
TCEB3BELOA2 | HsT832 | MGC119351 | TCEB3Ltranscription elongation factor B polypeptide 3B (elongin A2)Two-hybridBioGRID16189514 
THAP7MGC10963THAP domain containing 7Two-hybridBioGRID16189514 
TIFAMGC20791 | T2BP | T6BP | TIFAATRAF-interacting protein with forkhead-associated domainTwo-hybridBioGRID16189514 
-HPRD11798190 
TNFDIF | TNF-alpha | TNFA | TNFSF2tumor necrosis factor (TNF superfamily, member 2)Affinity Capture-WesternBioGRID12887920 
TNFAIP3A20 | MGC104522 | MGC138687 | MGC138688 | OTUD7C | TNFA1P2tumor necrosis factor, alpha-induced protein 3-HPRD,BioGRID8692885 
TNFRSF11ACD265 | FEO | LOH18CR1 | ODFR | OFE | OPTB7 | OSTS | PDB2 | RANK | TRANCERtumor necrosis factor receptor superfamily, member 11a, NFKB activatorAffinity Capture-Western
Reconstituted Complex
BioGRID9685412 |9852070 
|10025951 |10075662 
-HPRD9774460 |9852070 
|10025951 
TNFRSF12ACD266 | FN14 | TWEAKRtumor necrosis factor receptor superfamily, member 12A-HPRD,BioGRID11728344 
TNFRSF13BCD267 | CVID | FLJ39942 | MGC133214 | MGC39952 | TACI | TNFRSF14Btumor necrosis factor receptor superfamily, member 13B-HPRD,BioGRID10880535 
TNFRSF14ATAR | HVEA | HVEM | LIGHTR | TR2tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator)-HPRD,BioGRID9153189 |9162022 
TNFRSF17BCM | BCMA | CD269tumor necrosis factor receptor superfamily, member 17-HPRD,BioGRID10903733 
TNFRSF18AITR | GITR | GITR-Dtumor necrosis factor receptor superfamily, member 18-HPRD,BioGRID10037686 
TNFRSF19TAJ | TAJ-alpha | TRADE | TROYtumor necrosis factor receptor superfamily, member 19-HPRD,BioGRID10809768 
TNFRSF1ACD120a | FPF | MGC19588 | TBP1 | TNF-R | TNF-R-I | TNF-R55 | TNFAR | TNFR1 | TNFR55 | TNFR60 | p55 | p55-R | p60tumor necrosis factor receptor superfamily, member 1A-HPRD,BioGRID8565075 
TNFRSF1BCD120b | TBPII | TNF-R-II | TNF-R75 | TNFBR | TNFR1B | TNFR2 | TNFR80 | p75 | p75TNFRtumor necrosis factor receptor superfamily, member 1BTRAF2 interacts with TRAF1. This interaction was modeled on a demonstrated interaction between human TRAF2 and TNF-R2 from an unspecified species.BIND8702708 
-HPRD7639698 |8702708 
|9461607 |11907088 
Affinity Capture-MS
Affinity Capture-Western
Reconstituted Complex
Two-hybrid
BioGRID7639698 |8702708 
|8710854 |9162022 
|11907088 |14743216 
TNFRSF4ACT35 | CD134 | OX40 | TXGP1Ltumor necrosis factor receptor superfamily, member 4-HPRD,BioGRID9418902 
TNFRSF8CD30 | D1S166E | KI-1tumor necrosis factor receptor superfamily, member 8-HPRD8943059 |8999898 
-HPRD,BioGRID8627180 |8943059 
|8999898 |9168896 
|9353251 |11971184|8943059 
|8999898 
TRAF2 interacts with CD30.BIND8662842 
TNFRSF94-1BB | CD137 | CDw137 | ILA | MGC2172tumor necrosis factor receptor superfamily, member 9-HPRD,BioGRID9464265 
TNFSF14CD258 | HVEML | LIGHT | LTg | TR2tumor necrosis factor (ligand) superfamily, member 14Affinity Capture-MS
Affinity Capture-Western
BioGRID12571250 
TNFSF4CD134L | CD252 | GP34 | OX-40L | OX4OL | TXGP1tumor necrosis factor (ligand) superfamily, member 4-HPRD9418902 
TNFSF94-1BB-L | CD137Ltumor necrosis factor (ligand) superfamily, member 9-HPRD,BioGRID9607925 
TNIK-TRAF2 and NCK interacting kinase-HPRD,BioGRID10521462 
TRADDHs.89862 | MGC11078TNFRSF1A-associated via death domain-HPRD,BioGRID8565075 |8702708 
|10892748 
TRAF2 interacts with TRADD. This interaction was modeled on a demonstrated interaction between human TRAF2 and TRADD from an unspecified species.BIND8702708 
TRADD interacts with TRAF2. This interaction was modeled on a demonstrated interaction between TRADD and TRAF2, both from an unspecified species.BIND12796506 
TRAF1EBI6 | MGC:10353TNF receptor-associated factor 1TRAF2 interacts with TRAF1. This interaction was modeled on a demonstrated interaction between human TRAF2 and mouse TRAF1.BIND8702708 
-HPRD,BioGRID8702708 
TRAF2MGC:45012 | TRAP | TRAP3TNF receptor-associated factor 2-HPRD,BioGRID8702708 
TRAF3IP2ACT1 | C6orf2 | C6orf4 | C6orf5 | C6orf6 | CIKS | DKFZp586G0522 | MGC3581TRAF3 interacting protein 2Two-hybridBioGRID16189514 
TRAF6MGC:3310 | RNF85TNF receptor-associated factor 6Two-hybridBioGRID16189514 
TRAIPRNF206 | TRIPTRAF interacting protein-HPRD,BioGRID9104814 
TRIM31C6orf13 | HCG1 | HCGI | RNFtripartite motif-containing 31Two-hybridBioGRID16189514 
TRIM37KIAA0898 | MUL | POB1 | TEF3tripartite motif-containing 37-HPRD,BioGRID11279055 
TRPC4APC20orf188 | TRRP4AP | TRUSStransient receptor potential cation channel, subfamily C, member 4 associated proteinAffinity Capture-WesternBioGRID14585990 
TRPT1MGC11134tRNA phosphotransferase 1Two-hybridBioGRID16189514 
TTRAPAD022 | EAP2 | MGC111021 | MGC9099 | dJ30M3.3TRAF and TNF receptor associated protein-HPRD,BioGRID10764746 
TUBA3CTUBA2 | bA408E5.3tubulin, alpha 3c-HPRD14743216 
UBXN11COA-1 | DKFZp686F04228 | PP2243 | SOC | SOCI | UBXD5UBX domain protein 11Two-hybridBioGRID16189514 
USP2UBP41 | USP9ubiquitin specific peptidase 2Two-hybridBioGRID16189514 
USP53DKFZp781E1417ubiquitin specific peptidase 53Two-hybridBioGRID16189514 
USP7HAUSP | TEF1ubiquitin specific peptidase 7 (herpes virus-associated)-HPRD,BioGRID11279055 
ZBTB16PLZF | ZNF145zinc finger and BTB domain containing 16Two-hybridBioGRID16189514 
ZBTB25KUP | ZNF46zinc finger and BTB domain containing 25Two-hybridBioGRID16189514 
ZBTB43ZBTB22B | ZNF-X | ZNF297Bzinc finger and BTB domain containing 43Two-hybridBioGRID16189514 
ZFAND6AWP1 | ZA20D3 | ZFAND5Bzinc finger, AN1-type domain 6Two-hybridBioGRID16189514 
ZNF205ZNF210 | Zfp13zinc finger protein 205Two-hybridBioGRID16189514 
ZNF646KIAA0296zinc finger protein 646Two-hybridBioGRID16189514 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_MAPK_SIGNALING_PATHWAY 267205All SZGR genes in this pathway
KEGG_APOPTOSIS 8862All SZGR genes in this pathway
KEGG_RIG_I_LIKE_RECEPTOR_SIGNALING_PATHWAY 7151All SZGR genes in this pathway
KEGG_ADIPOCYTOKINE_SIGNALING_PATHWAY 6757All SZGR genes in this pathway
KEGG_PATHWAYS_IN_CANCER 328259All SZGR genes in this pathway
KEGG_SMALL_CELL_LUNG_CANCER 8467All SZGR genes in this pathway
BIOCARTA_CERAMIDE_PATHWAY 2216All SZGR genes in this pathway
BIOCARTA_HIVNEF_PATHWAY 5843All SZGR genes in this pathway
BIOCARTA_DEATH_PATHWAY 3324All SZGR genes in this pathway
BIOCARTA_KERATINOCYTE_PATHWAY 4638All SZGR genes in this pathway
BIOCARTA_MAPK_PATHWAY 8768All SZGR genes in this pathway
BIOCARTA_P38MAPK_PATHWAY 4031All SZGR genes in this pathway
BIOCARTA_SODD_PATHWAY 107All SZGR genes in this pathway
BIOCARTA_TALL1_PATHWAY 1515All SZGR genes in this pathway
BIOCARTA_41BB_PATHWAY 1715All SZGR genes in this pathway
BIOCARTA_STRESS_PATHWAY 2518All SZGR genes in this pathway
BIOCARTA_TNFR1_PATHWAY 2921All SZGR genes in this pathway
BIOCARTA_TNFR2_PATHWAY 1815All SZGR genes in this pathway
ST_TUMOR_NECROSIS_FACTOR_PATHWAY 2920All SZGR genes in this pathway
SIG_CD40PATHWAYMAP 3428All SZGR genes in this pathway
ST_FAS_SIGNALING_PATHWAY 6554All SZGR genes in this pathway
PID_P38_MKK3_6PATHWAY 2621All SZGR genes in this pathway
PID_CD40_PATHWAY 3126All SZGR genes in this pathway
PID_TRAIL_PATHWAY 2820All SZGR genes in this pathway
PID_TNF_PATHWAY 4633All SZGR genes in this pathway
PID_CERAMIDE_PATHWAY 4837All SZGR genes in this pathway
PID_HIV_NEF_PATHWAY 3526All SZGR genes in this pathway
PID_CASPASE_PATHWAY 5239All SZGR genes in this pathway
REACTOME_EXTRINSIC_PATHWAY_FOR_APOPTOSIS 138All SZGR genes in this pathway
REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION 3026All SZGR genes in this pathway
REACTOME_TRAF6_MEDIATED_NFKB_ACTIVATION 2117All SZGR genes in this pathway
REACTOME_RIG_I_MDA5_MEDIATED_INDUCTION_OF_IFN_ALPHA_BETA_PATHWAYS 7357All SZGR genes in this pathway
REACTOME_APOPTOSIS 14894All SZGR genes in this pathway
REACTOME_INNATE_IMMUNE_SYSTEM 279178All SZGR genes in this pathway
REACTOME_IMMUNE_SYSTEM 933616All SZGR genes in this pathway
DOANE_RESPONSE_TO_ANDROGEN_DN 241146All SZGR genes in this pathway
GINESTIER_BREAST_CANCER_ZNF217_AMPLIFIED_DN 335193All SZGR genes in this pathway
GRAESSMANN_APOPTOSIS_BY_DOXORUBICIN_DN 17811082All SZGR genes in this pathway
GRAESSMANN_RESPONSE_TO_MC_AND_DOXORUBICIN_DN 770415All SZGR genes in this pathway
DARWICHE_SKIN_TUMOR_PROMOTER_UP 14296All SZGR genes in this pathway
DARWICHE_PAPILLOMA_RISK_LOW_UP 162104All SZGR genes in this pathway
DARWICHE_PAPILLOMA_RISK_HIGH_UP 147101All SZGR genes in this pathway
DARWICHE_SQUAMOUS_CELL_CARCINOMA_DN 181107All SZGR genes in this pathway
DARWICHE_PAPILLOMA_PROGRESSION_RISK 7444All SZGR genes in this pathway
DUTTA_APOPTOSIS_VIA_NFKB 3325All SZGR genes in this pathway
SCHEIDEREIT_IKK_INTERACTING_PROTEINS 5845All SZGR genes in this pathway
DARWICHE_PAPILLOMA_RISK_HIGH_VS_LOW_UP 66All SZGR genes in this pathway
YAGI_AML_SURVIVAL 12987All SZGR genes in this pathway
ZHANG_ANTIVIRAL_RESPONSE_TO_RIBAVIRIN_DN 5132All SZGR genes in this pathway
IVANOVA_HEMATOPOIESIS_STEM_CELL_AND_PROGENITOR 681420All SZGR genes in this pathway
MONNIER_POSTRADIATION_TUMOR_ESCAPE_UP 393244All SZGR genes in this pathway
DANG_REGULATED_BY_MYC_UP 7253All SZGR genes in this pathway
ZEMBUTSU_SENSITIVITY_TO_MITOMYCIN 1911All SZGR genes in this pathway
BRUINS_UVC_RESPONSE_EARLY_LATE 317190All SZGR genes in this pathway
WAKABAYASHI_ADIPOGENESIS_PPARG_RXRA_BOUND_8D 882506All SZGR genes in this pathway


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