Gene Page: TSHB

Summary
GeneID  7252
Symbol  TSHB
Synonyms  CHNG4|TSH-BETA
Description  thyroid stimulating hormone, beta
See related  HGNC:12372|MIM:188540|Ensembl:ENSG00000134200|HPRD:11766|
Locus tag  -
Gene type  protein-coding
Map location  1p13
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_Igenome scan meta-analysisPsr: 0.0235 
GSMA_IIAgenome scan meta-analysis (All samples)Psr: 0.00814 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
NDUFS40.820.85
SEC61G0.780.75
ATP5O0.770.79
ATP5E0.760.77
C11orf730.760.78
C20orf240.760.71
NOP100.760.73
PHPT10.760.71
NTAN10.750.73
C11orf740.740.80
Top 10 negatively co-expressed genes
MYH9-0.56-0.59
CASKIN2-0.50-0.60
FAM38A-0.46-0.54
PTRF-0.46-0.51
TRIM56-0.46-0.54
NPR1-0.45-0.52
PEAR1-0.45-0.52
MMRN2-0.45-0.48
SDPR-0.44-0.46
SHE-0.44-0.49
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005179hormone activityTAS2792087 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0007186G-protein coupled receptor protein signaling pathwayTAS2792087 
GO:0007267cell-cell signalingTAS2792087 
GO:0009653anatomical structure morphogenesisTAS2792087 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005576extracellular regionIEA-
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
CGACG-ALPHA | FSHA | GPHA1 | GPHa | HCG | LHA | TSHAglycoprotein hormones, alpha polypeptide-HPRD,BioGRID3839756 |5002675 
TSHRCHNG1 | LGR3 | MGC75129 | hTSHR-Ithyroid stimulating hormone receptor-HPRD2558651 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_NEUROACTIVE_LIGAND_RECEPTOR_INTERACTION 272195All SZGR genes in this pathway
KEGG_AUTOIMMUNE_THYROID_DISEASE 5349All SZGR genes in this pathway
ST_WNT_BETA_CATENIN_PATHWAY 3428All SZGR genes in this pathway
REACTOME_METABOLISM_OF_AMINO_ACIDS_AND_DERIVATIVES 200136All SZGR genes in this pathway
REACTOME_SIGNALING_BY_GPCR 920449All SZGR genes in this pathway
REACTOME_CLASS_A1_RHODOPSIN_LIKE_RECEPTORS 305177All SZGR genes in this pathway
REACTOME_GLYCOPROTEIN_HORMONES 128All SZGR genes in this pathway
REACTOME_PEPTIDE_HORMONE_BIOSYNTHESIS 1410All SZGR genes in this pathway
REACTOME_AMINE_DERIVED_HORMONES 1512All SZGR genes in this pathway
REACTOME_HORMONE_LIGAND_BINDING_RECEPTORS 108All SZGR genes in this pathway
REACTOME_GPCR_DOWNSTREAM_SIGNALING 805368All SZGR genes in this pathway
REACTOME_G_ALPHA_S_SIGNALLING_EVENTS 12182All SZGR genes in this pathway
REACTOME_GPCR_LIGAND_BINDING 408246All SZGR genes in this pathway
DEURIG_T_CELL_PROLYMPHOCYTIC_LEUKEMIA_UP 368234All SZGR genes in this pathway
SHETH_LIVER_CANCER_VS_TXNIP_LOSS_PAM4 261153All SZGR genes in this pathway
BYSTRYKH_HEMATOPOIESIS_STEM_CELL_AND_BRAIN_QTL_TRANS 185114All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_16HR_DN 8662All SZGR genes in this pathway
KAYO_AGING_MUSCLE_UP 244165All SZGR genes in this pathway
XU_GH1_EXOGENOUS_TARGETS_UP 8550All SZGR genes in this pathway
TSENG_IRS1_TARGETS_UP 11371All SZGR genes in this pathway
WANG_LSD1_TARGETS_DN 3930All SZGR genes in this pathway
MATZUK_CENTRAL_FOR_FEMALE_FERTILITY 2925All SZGR genes in this pathway
BRUINS_UVC_RESPONSE_VIA_TP53_GROUP_B 549316All SZGR genes in this pathway


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