Gene Page: TUBG1

Summary
GeneID  7283
Symbol  TUBG1
Synonyms  TUBG|TUBGCP1
Description  tubulin, gamma 1
See related  HGNC:12417|MIM:191135|Ensembl:ENSG00000131462|HPRD:01853|
Locus tag  -
Gene type  protein-coding
Map location  17q21
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
NetworkShortest path distance of core genes in the Human protein-protein interaction networkContribution to shortest path in PPI network: 0.0833 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
MRPS270.910.90
KPNA40.900.91
NPEPPS0.900.89
GOLGA50.890.89
ATF20.890.90
CUL10.890.89
SPOP0.890.89
VPS37A0.890.89
ARMC10.890.90
PSMD110.890.88
Top 10 negatively co-expressed genes
MT-CO2-0.81-0.82
AF347015.31-0.80-0.81
AF347015.8-0.79-0.81
MT-CYB-0.78-0.80
AF347015.21-0.77-0.79
AF347015.2-0.77-0.81
AF347015.33-0.77-0.78
AF347015.27-0.76-0.78
AF347015.15-0.75-0.79
AF347015.26-0.75-0.78
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0000166nucleotide bindingIEA-
GO:0003924GTPase activityIEA-
GO:0005515protein bindingIPI9566969 |17286961 
GO:0005525GTP bindingIEA-
GO:0005200structural constituent of cytoskeletonTAS1904010 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0000212meiotic spindle organizationISS-
GO:0000226microtubule cytoskeleton organizationTAS1904010 
GO:0051258protein polymerizationIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0000242pericentriolar materialIEA-
GO:0000794condensed nuclear chromosomeISS-
GO:0000930gamma-tubulin complexTAS9566969 
GO:0005816spindle pole bodyTAS1904010 
GO:0005827polar microtubuleIDA9566969 
GO:0005881cytoplasmic microtubuleIEA-
GO:0005737cytoplasmIDA9566969 
GO:0005737cytoplasmISS-
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
BRCA1BRCAI | BRCC1 | IRIS | PSCP | RNF53breast cancer 1, early onset-HPRD,BioGRID9789027 |11691781 
CENPJBM032 | CPAP | LAP | LIP1 | MCPH6 | MGC131581 | MGC131582 | MGC142222 | MGC142224centromere protein JAffinity Capture-WesternBioGRID11003675 
MARK4FLJ90097 | KIAA1860 | MARKL1 | Nbla00650MAP/microtubule affinity-regulating kinase 4Affinity Capture-MS
Affinity Capture-Western		BioGRID14594945 
NDE1FLJ20101 | HOM-TES-87 | NUDE | NUDE1nudE nuclear distribution gene E homolog 1 (A. nidulans)Affinity Capture-WesternBioGRID11163258 
NUP85FLJ12549 | Nup75nucleoporin 85kDa-HPRD7592789 
PCNTKEN | MOPD2 | PCN | PCNT2 | PCNTB | PCTN2 | SCKL4pericentrin-HPRD12221128 
PIK3R1GRB1 | p85 | p85-ALPHAphosphoinositide-3-kinase, regulatory subunit 1 (alpha)-HPRD7592789 
PXNFLJ16691paxillin-HPRD,BioGRID10840040 |11950600 
RAB8BFLJ38125RAB8B, member RAS oncogene familyAffinity Capture-WesternBioGRID12639940 
RACGAP1HsCYK-4 | ID-GAP | MgcRacGAPRac GTPase activating protein 1-HPRD11942621 
RASSF1123F2 | NORE2A | RASSF1A | RDA32 | REH3P21Ras association (RalGDS/AF-6) domain family member 1-HPRD,BioGRID14603253 
RNF19ADKFZp566B1346 | DORFIN | RNF19ring finger protein 19A-HPRD11237715 
SPATC1MGC61633 | SPATA15 | SPERIOLINspermatogenesis and centriole associated 1Affinity Capture-WesternBioGRID15280373 
TUBA1BK-ALPHA-1tubulin, alpha 1b-HPRD11082048 
TUBA3CTUBA2 | bA408E5.3tubulin, alpha 3c-HPRD11082048 
TUBGCP3GCP3 | SPBC98 | Spc98ptubulin, gamma complex associated protein 3-HPRD9566969 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
PID_PLK1_PATHWAY 4625All SZGR genes in this pathway
REACTOME_CELL_CYCLE 421253All SZGR genes in this pathway
REACTOME_CELL_CYCLE_MITOTIC 325185All SZGR genes in this pathway
REACTOME_RECRUITMENT_OF_MITOTIC_CENTROSOME_PROTEINS_AND_COMPLEXES 6643All SZGR genes in this pathway
REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES 5938All SZGR genes in this pathway
REACTOME_RECRUITMENT_OF_NUMA_TO_MITOTIC_CENTROSOMES 108All SZGR genes in this pathway
REACTOME_MITOTIC_G2_G2_M_PHASES 8150All SZGR genes in this pathway
NAKAMURA_TUMOR_ZONE_PERIPHERAL_VS_CENTRAL_UP 285181All SZGR genes in this pathway
FOURNIER_ACINAR_DEVELOPMENT_LATE_DN 2113All SZGR genes in this pathway
TIEN_INTESTINE_PROBIOTICS_24HR_UP 557331All SZGR genes in this pathway
KINSEY_TARGETS_OF_EWSR1_FLII_FUSION_UP 1278748All SZGR genes in this pathway
RODRIGUES_THYROID_CARCINOMA_POORLY_DIFFERENTIATED_UP 633376All SZGR genes in this pathway
ENK_UV_RESPONSE_EPIDERMIS_UP 293179All SZGR genes in this pathway
BERENJENO_TRANSFORMED_BY_RHOA_UP 536340All SZGR genes in this pathway
PATIL_LIVER_CANCER 747453All SZGR genes in this pathway
PUJANA_BREAST_CANCER_LIT_INT_NETWORK 10173All SZGR genes in this pathway
LOPEZ_MBD_TARGETS 957597All SZGR genes in this pathway
BENPORATH_NANOG_TARGETS 988594All SZGR genes in this pathway
BENPORATH_SOX2_TARGETS 734436All SZGR genes in this pathway
BENPORATH_MYC_MAX_TARGETS 775494All SZGR genes in this pathway
STARK_PREFRONTAL_CORTEX_22Q11_DELETION_DN 517309All SZGR genes in this pathway
BASSO_B_LYMPHOCYTE_NETWORK 14396All SZGR genes in this pathway
MANALO_HYPOXIA_DN 289166All SZGR genes in this pathway
TARTE_PLASMA_CELL_VS_PLASMABLAST_DN 309206All SZGR genes in this pathway
PENG_RAPAMYCIN_RESPONSE_DN 245154All SZGR genes in this pathway
PENG_GLUTAMINE_DEPRIVATION_DN 337230All SZGR genes in this pathway
LEI_MYB_TARGETS 318215All SZGR genes in this pathway
ALCALAY_AML_BY_NPM1_LOCALIZATION_DN 184132All SZGR genes in this pathway
ZHANG_RESPONSE_TO_CANTHARIDIN_DN 6946All SZGR genes in this pathway
BANDRES_RESPONSE_TO_CARMUSTIN_WITHOUT_MGMT_48HR_DN 3225All SZGR genes in this pathway
BANDRES_RESPONSE_TO_CARMUSTIN_MGMT_48HR_DN 161105All SZGR genes in this pathway
CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_2 473224All SZGR genes in this pathway
MARSON_BOUND_BY_FOXP3_STIMULATED 1022619All SZGR genes in this pathway
MARSON_BOUND_BY_FOXP3_UNSTIMULATED 1229713All SZGR genes in this pathway
HELLER_HDAC_TARGETS_SILENCED_BY_METHYLATION_UP 461298All SZGR genes in this pathway
SARRIO_EPITHELIAL_MESENCHYMAL_TRANSITION_UP 180114All SZGR genes in this pathway
BLUM_RESPONSE_TO_SALIRASIB_DN 342220All SZGR genes in this pathway
CHANG_CORE_SERUM_RESPONSE_UP 212128All SZGR genes in this pathway
SHEDDEN_LUNG_CANCER_POOR_SURVIVAL_A6 456285All SZGR genes in this pathway
BOYAULT_LIVER_CANCER_SUBCLASS_G23_UP 5235All SZGR genes in this pathway
KOBAYASHI_EGFR_SIGNALING_24HR_DN 251151All SZGR genes in this pathway
FOURNIER_ACINAR_DEVELOPMENT_LATE_2 277172All SZGR genes in this pathway
CAIRO_HEPATOBLASTOMA_CLASSES_UP 605377All SZGR genes in this pathway
DANG_BOUND_BY_MYC 1103714All SZGR genes in this pathway
CHICAS_RB1_TARGETS_SENESCENT 572352All SZGR genes in this pathway
BRUINS_UVC_RESPONSE_LATE 1137655All SZGR genes in this pathway
LIM_MAMMARY_LUMINAL_MATURE_UP 11665All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-124.12632m8hsa-miR-124aUUAAGGCACGCGGUGAAUGCCA
miR-124/50626321Ahsa-miR-506UAAGGCACCCUUCUGAGUAGA
hsa-miR-124brainUAAGGCACGCGGUGAAUGCC
miR-125/35181871Ahsa-miR-125bbrainUCCCUGAGACCCUAACUUGUGA
hsa-miR-125abrainUCCCUGAGACCCUUUAACCUGUG
miR-1991811871Ahsa-miR-199aCCCAGUGUUCAGACUACCUGUUC
hsa-miR-199bCCCAGUGUUUAGACUAUCUGUUC
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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