Gene Page: UCP1

Summary
GeneID  7350
Symbol  UCP1
Synonyms  SLC25A7|UCP
Description  uncoupling protein 1 (mitochondrial, proton carrier)
See related  HGNC:12517|MIM:113730|Ensembl:ENSG00000109424|HPRD:00221|
Locus tag  -
Gene type  protein-coding
Map location  4q28-q31
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 1 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
Top 10 negatively co-expressed genes
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005515protein bindingIEA-
GO:0005215transporter activityIEA-
GO:0017077oxidative phosphorylation uncoupler activityIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006839mitochondrial transportIEAglutamate (GO term level: 6)-
GO:0006810transportIEA-
GO:0015992proton transportTAS2380264 
GO:0050873brown fat cell differentiationISS-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005739mitochondrionIEA-
GO:0005740mitochondrial envelopeIEA-
GO:0005743mitochondrial inner membraneNAS2380264 
GO:0016020membraneIEA-
GO:0016021integral to membraneIEA-
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
CIDEACIDE-Acell death-inducing DFFA-like effector a-HPRD12910269 
TOMM20KIAA0016 | MAS20 | MGC117367 | MOM19 | TOM20translocase of outer mitochondrial membrane 20 homolog (yeast)Reconstituted ComplexBioGRID9119086 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_PPAR_SIGNALING_PATHWAY 6947All SZGR genes in this pathway
KEGG_HUNTINGTONS_DISEASE 185109All SZGR genes in this pathway
REACTOME_TCA_CYCLE_AND_RESPIRATORY_ELECTRON_TRANSPORT 14185All SZGR genes in this pathway
REACTOME_RESPIRATORY_ELECTRON_TRANSPORT_ATP_SYNTHESIS_BY_CHEMIOSMOTIC_COUPLING_AND_HEAT_PRODUCTION_BY_UNCOUPLING_PROTEINS_ 9856All SZGR genes in this pathway
MCBRYAN_PUBERTAL_BREAST_4_5WK_DN 196131All SZGR genes in this pathway
BENPORATH_SUZ12_TARGETS 1038678All SZGR genes in this pathway
BENPORATH_EED_TARGETS 1062725All SZGR genes in this pathway
BENPORATH_ES_WITH_H3K27ME3 1118744All SZGR genes in this pathway
BENPORATH_PRC2_TARGETS 652441All SZGR genes in this pathway
BYSTRYKH_HEMATOPOIESIS_STEM_CELL_AND_BRAIN_QTL_TRANS 185114All SZGR genes in this pathway
FERNANDEZ_BOUND_BY_MYC 182116All SZGR genes in this pathway
BYSTRYKH_HEMATOPOIESIS_STEM_CELL_QTL_TRANS 882572All SZGR genes in this pathway
HOWLIN_CITED1_TARGETS_2_UP 1710All SZGR genes in this pathway
MARTINEZ_RB1_TARGETS_DN 543317All SZGR genes in this pathway
MARTINEZ_TP53_TARGETS_UP 602364All SZGR genes in this pathway
MARTINEZ_RB1_AND_TP53_TARGETS_UP 601369All SZGR genes in this pathway
MOOTHA_HUMAN_MITODB_6_2002 429260All SZGR genes in this pathway
MOOTHA_MITOCHONDRIA 447277All SZGR genes in this pathway
MIKKELSEN_MCV6_ICP_WITH_H3K4ME3_AND_H3K27ME3 3421All SZGR genes in this pathway
MIKKELSEN_MEF_ICP_WITH_H3K27ME3 206108All SZGR genes in this pathway
MIKKELSEN_IPS_ICP_WITH_H3K4ME3_AND_H327ME3 12683All SZGR genes in this pathway
DANG_BOUND_BY_MYC 1103714All SZGR genes in this pathway
MIKKELSEN_ES_ICP_WITH_H3K4ME3_AND_H3K27ME3 13785All SZGR genes in this pathway
WAKABAYASHI_ADIPOGENESIS_PPARG_RXRA_BOUND_8D 882506All SZGR genes in this pathway


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