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Association Linkage Expression Literature GO_Annotation Gene Network miRNA Targets

Gene Ranking Integration

Association Linkage Expression Literature GO_Annotation Gene Network miRNA Targets Datasets Gene Ranking

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Gene Page: YES1

Summary

GeneID

7525

Symbol

YES1

Synonyms

HsT441|P61-YES|Yes|c-yes

Description

v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1

Locus tag

Gene type

protein-coding

Map location

18p11.31-p11.21

Gene in Data Sources

Gene set name

Method of gene set

Evidence

Info

Network

Shortest path distance of core genes in the Human protein-protein interaction network

Contribution to shortest path in PPI network: 0.0607

General Gene Expression (microarray) ?

Gene Expression in Brain Regions (new)

Top co-expressed genes in Brain Regions (new)

Gene

Pearson's Correlation

Spearman's Correlation

Top 10 positively co-expressed genes

HNRNPF

0.92

0.84

NUP107

0.90

0.88

LRRC42

0.90

0.82

E2F5

0.90

0.78

RYK

0.90

0.82

UNG

0.89

0.81

CTPS2

0.89

0.86

ODC1

0.89

0.81

KATNA1

0.89

0.83

RRM1

0.89

0.85

Top 10 negatively co-expressed genes

HLA-F

-0.65

-0.73

FBXO2

-0.63

-0.66

PTH1R

-0.63

-0.71

C5orf53

-0.62

-0.66

AF347015.27

-0.62

-0.79

ASPHD1

-0.61

-0.62

TINAGL1

-0.61

-0.71

CA4

-0.61

-0.73

TNFSF12

-0.61

-0.65

AF347015.31

-0.61

-0.79

Gene Ontology

Molecular function

GO term

Evidence

Neuro keywords

PubMed ID

GO:0000166

nucleotide binding

IEA

GO:0005515

protein binding

IPI

1715582 |17254967 |18328427

GO:0005524

ATP binding

IEA

GO:0004715

non-membrane spanning protein tyrosine kinase activity

IEA

GO:0016740

transferase activity

IEA

Biological process

GO term

Evidence

Neuro keywords

PubMed ID

GO:0006464

protein modification process

TAS

2436037

GO:0006468

protein amino acid phosphorylation

IEA

GO:0015758

glucose transport

IEA

Cellular component

GO term

Evidence

Neuro keywords

PubMed ID

GO:0005737

cytoplasm

IEA

Protein-protein Interactions

Shown by network

Interactors	Aliases B	Official full name B	Experimental	Source	PubMed ID
ADAM12	MCMP \| MCMPMltna \| MLTN \| MLTNA	ADAM metallopeptidase domain 12	-	HPRD	11127814
CD2AP	CMS \| DKFZp586H0519	CD2-associated protein	-	HPRD	10339567
CD36	CHDS7 \| FAT \| GP3B \| GP4 \| GPIV \| PASIV \| SCARB3	CD36 molecule (thrombospondin receptor)	-	HPRD	7521304
CD36	CHDS7 \| FAT \| GP3B \| GP4 \| GPIV \| PASIV \| SCARB3	CD36 molecule (thrombospondin receptor)	Affinity Capture-Western	BioGRID	1715582
CD46	MCP \| MGC26544 \| MIC10 \| TLX \| TRA2.10	CD46 molecule, complement regulatory protein	-	HPRD,BioGRID	11901164
CDH1	Arc-1 \| CD324 \| CDHE \| ECAD \| LCAM \| UVO	cadherin 1, type 1, E-cadherin (epithelial)	Reconstituted Complex	BioGRID	12640114
CSF1R	C-FMS \| CD115 \| CSFR \| FIM2 \| FMS	colony stimulating factor 1 receptor	-	HPRD,BioGRID	7681396
CTNND1	CAS \| CTNND \| KIAA0384 \| P120CAS \| P120CTN \| p120	catenin (cadherin-associated protein), delta 1	Affinity Capture-Western	BioGRID	12640114
DLG4	FLJ97752 \| FLJ98574 \| PSD95 \| SAP90	discs, large homolog 4 (Drosophila)	-	HPRD	9892651
DOK1	MGC117395 \| MGC138860 \| P62DOK	docking protein 1, 62kDa (downstream of tyrosine kinase 1)	Reconstituted Complex	BioGRID	11071635
FYN	MGC45350 \| SLK \| SYN	FYN oncogene related to SRC, FGR, YES	Affinity Capture-Western	BioGRID	12640114
JAK2	JTK10	Janus kinase 2 (a protein tyrosine kinase)	-	HPRD,BioGRID	8702385
KIT	C-Kit \| CD117 \| PBT \| SCFR	v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog	Reconstituted Complex	BioGRID	11071635
NPHS1	CNF \| NPHN	nephrosis 1, congenital, Finnish type (nephrin)	-	HPRD	12846735
NPHS1	CNF \| NPHN	nephrosis 1, congenital, Finnish type (nephrin)	Affinity Capture-Western	BioGRID	12668668
OCLN	-	occludin	-	HPRD,BioGRID	11950934
PECAM1	CD31 \| PECAM-1	platelet/endothelial cell adhesion molecule	-	HPRD,BioGRID	10858437
PTK2	FADK \| FAK \| FAK1 \| pp125FAK	PTK2 protein tyrosine kinase 2	Affinity Capture-Western	BioGRID	12558988
RASA1	CM-AVM \| CMAVM \| DKFZp434N071 \| GAP \| PKWS \| RASA \| RASGAP \| p120GAP \| p120RASGAP	RAS p21 protein activator (GTPase activating protein) 1	-	HPRD,BioGRID	1544885
RPL10	DKFZp686J1851 \| DXS648 \| DXS648E \| FLJ23544 \| FLJ27072 \| NOV \| QM	ribosomal protein L10	-	HPRD,BioGRID	12138090
SLC9A3R1	EBP50 \| NHERF \| NHERF1 \| NPHLOP2	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1	Reconstituted Complex	BioGRID	10562288
TP53BP2	53BP2 \| ASPP2 \| BBP \| PPP1R13A \| p53BP2	tumor protein p53 binding protein, 2	-	HPRD	11278422
TRPV4	OTRPC4 \| TRP12 \| VR-OAC \| VRL-2 \| VRL2 \| VROAC	transient receptor potential cation channel, subfamily V, member 4	-	HPRD,BioGRID	12538589
TYRO3	BYK \| Brt \| Dtk \| FLJ16467 \| RSE \| Sky \| Tif	TYRO3 protein tyrosine kinase	-	HPRD	7537495
YAP1	YAP \| YAP2 \| YAP65 \| YKI	Yes-associated protein 1, 65kDa	-	HPRD	10562288

miRNA Targets ?

miRNA family	Target position			miRNA ID	miRNA seq
miRNA family	UTR start	UTR end	Match method	miRNA ID	miRNA seq
miR-1/206	436	442	1A	hsa-miR-1	UGGAAUGUAAAGAAGUAUGUA
				hsa-miR-206^SZ	UGGAAUGUAAGGAAGUGUGUGG
				hsa-miR-613	AGGAAUGUUCCUUCUUUGCC
miR-125/351	945	951	1A	hsa-miR-125b^brain	UCCCUGAGACCCUAACUUGUGA
miR-125/351	945	951	1A	hsa-miR-125a^brain	UCCCUGAGACCCUUUAACCUGUG
miR-133	421	428	1A,m8	hsa-miR-133a	UUGGUCCCCUUCAACCAGCUGU
miR-133	421	428	1A,m8	hsa-miR-133b	UUGGUCCCCUUCAACCAGCUA
miR-140	142	148	m8	hsa-miR-140^brain	AGUGGUUUUACCCUAUGGUAG
miR-145	115	122	1A,m8	hsa-miR-145	GUCCAGUUUUCCCAGGAAUCCCUU
miR-17-5p/20/93.mr/106/519.d	959	965	m8	hsa-miR-17-5p	CAAAGUGCUUACAGUGCAGGUAGU
				hsa-miR-20a^brain	UAAAGUGCUUAUAGUGCAGGUAG
				hsa-miR-106a	AAAAGUGCUUACAGUGCAGGUAGC
				hsa-miR-106b^SZ	UAAAGUGCUGACAGUGCAGAU
				hsa-miR-20b^SZ	CAAAGUGCUCAUAGUGCAGGUAG
				hsa-miR-519d	CAAAGUGCCUCCCUUUAGAGUGU
miR-182	31	37	1A	hsa-miR-182	UUUGGCAAUGGUAGAACUCACA
miR-183	2012	2018	m8	hsa-miR-183	UAUGGCACUGGUAGAAUUCACUG
miR-205	713	719	m8	hsa-miR-205	UCCUUCAUUCCACCGGAGUCUG
miR-208	2513	2519	1A	hsa-miR-208	AUAAGACGAGCAAAAAGCUUGU
miR-23	2233	2239	1A	hsa-miR-23a^brain	AUCACAUUGCCAGGGAUUUCC
miR-23	2233	2239	1A	hsa-miR-23b^brain	AUCACAUUGCCAGGGAUUACC
miR-26	951	957	1A	hsa-miR-26a^brain	UUCAAGUAAUCCAGGAUAGGC
miR-26	951	957	1A	hsa-miR-26b^SZ	UUCAAGUAAUUCAGGAUAGGUU
miR-320	2495	2501	m8	hsa-miR-320	AAAAGCUGGGUUGAGAGGGCGAA
miR-381	2387	2393	1A	hsa-miR-381	UAUACAAGGGCAAGCUCUCUGU
miR-499	2513	2519	1A	hsa-miR-499	UUAAGACUUGCAGUGAUGUUUAA
miR-504	207	213	m8	hsa-miR-504	AGACCCUGGUCUGCACUCUAU
miR-96	31	37	1A	hsa-miR-96^brain	UUUGGCACUAGCACAUUUUUGC

SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.