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GeneID |
775
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Symbol |
CACNA1C
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Synonyms |
CACH2|CACN2|CACNL1A1|CCHL1A1|CaV1.2|MGC120730|TS
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Description |
calcium channel, voltage-dependent, L type, alpha 1C subunit |
See related |
HGNC:1390|MIM:114205|HPRD:00246| |
Locus tag |
- |
Gene type |
protein-coding |
Map location |
12p13.3 |
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Gene set name |
Method of gene set |
Evidence |
Info |
Literature | High-throughput literature-search | Co-occurance with Schizophrenia keywords: [schizophrenias, schizophrenia] | Click to show detail | GO_Annotation | Mapping neuro-related keywords to Gene Ontology annotations | Hits with neuro-related keywords: 1 | | Network | Shortest path distance of core genes in the Human protein-protein interaction network | Contribution to shortest path in PPI network: 0.0047 | |
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General Gene Expression (microarray) ? |
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Gene Expression in Brain Regions (new) |
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Top co-expressed genes in Brain Regions (new) |
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Gene | Pearson's Correlation | Spearman's Correlation | | |
Top 10 positively co-expressed genes |
CYP46A1 | 0.80 | 0.85 | | |
TMEM38A | 0.75 | 0.83 | | |
GRASP | 0.75 | 0.81 | | |
ADAMTS8 | 0.74 | 0.76 | | |
FBXL16 | 0.73 | 0.75 | | |
STIM1 | 0.73 | 0.73 | | |
STAT6 | 0.73 | 0.81 | | |
DDN | 0.72 | 0.75 | | |
PACSIN1 | 0.72 | 0.79 | | |
CTSB | 0.71 | 0.67 | | |
Top 10 negatively co-expressed genes | KIAA1949 | -0.58 | -0.55 | | |
TUBB2B | -0.58 | -0.59 | | |
TRAF4 | -0.56 | -0.64 | | |
ZNF311 | -0.55 | -0.56 | | |
DYNLT1 | -0.55 | -0.70 | | |
PPAPDC1B | -0.55 | -0.52 | | |
ZNF300 | -0.55 | -0.51 | | |
RBMX2 | -0.55 | -0.69 | | |
TIGD1 | -0.55 | -0.55 | | |
YBX1 | -0.54 | -0.57 | | |
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Molecular function | GO term | Evidence | Neuro keywords | PubMed ID |
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GO:0005509 | calcium ion binding | IEA | | - |
GO:0005516 | calmodulin binding | IPI | | 15140941 |
GO:0005244 | voltage-gated ion channel activity | IEA | | - |
GO:0005245 | voltage-gated calcium channel activity | IEA | | - |
GO:0005216 | ion channel activity | IEA | | - |
GO:0015270 | dihydropyridine-sensitive calcium channel activity | IDA | | 8392192 |
Biological process | GO term | Evidence | Neuro keywords | PubMed ID |
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GO:0007204 | elevation of cytosolic calcium ion concentration | IDA | | 12130699 |
GO:0006816 | calcium ion transport | IEA | | - |
GO:0006811 | ion transport | IEA | | - |
Cellular component | GO term | Evidence | Neuro keywords | PubMed ID |
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GO:0014069 | postsynaptic density | IDA | Synap (GO term level: 10) | 14140941 |
GO:0005737 | cytoplasm | IDA | | 11206130 |
GO:0016020 | membrane | IEA | | - |
GO:0016021 | integral to membrane | IDA | | 8392192 |
GO:0016021 | integral to membrane | IEA | | - |
GO:0005886 | plasma membrane | IDA | | 11206130 |
GO:0005891 | voltage-gated calcium channel complex | IDA | | 12130699 |
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- SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
- Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.
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