Gene Page: CACNA1E

Summary
GeneID  777
Symbol  CACNA1E
Synonyms  BII|CACH6|CACNL1A6|Cav2.3
Description  calcium channel, voltage-dependent, R type, alpha 1E subunit
See related  HGNC:1392|MIM:601013|HPRD:03006|
Locus tag  -
Gene type  protein-coding
Map location  1q25-q31
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 1 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
ATP13A30.890.92
PCYOX10.880.93
ZBTB380.880.93
ARHGAP200.880.94
FAM160B10.860.92
EDEM30.860.91
GNAQ0.860.91
CAMSAP1L10.850.92
NRXN10.850.92
SLC41A20.840.90
Top 10 negatively co-expressed genes
C11orf67-0.59-0.68
HSD17B14-0.59-0.69
FXYD1-0.58-0.68
EIF4EBP3-0.58-0.68
ACSF2-0.57-0.68
TLCD1-0.57-0.67
AF347015.31-0.56-0.67
HIGD1B-0.56-0.70
MT-CO2-0.56-0.68
RAB34-0.56-0.69
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005509calcium ion bindingIEA-
GO:0005244voltage-gated ion channel activityIEA-
GO:0005245voltage-gated calcium channel activityTAS8071363 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0007268synaptic transmissionTASneuron, Synap, Neurotransmitter (GO term level: 6)8071363 
GO:0006816calcium ion transportIEA-
GO:0006811ion transportIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0016021integral to membraneIEA-
GO:0005886plasma membraneEXP8825650 
GO:0005891voltage-gated calcium channel complexTAS8071363 
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
EFHC1EJM | EJM1 | FLJ10466 | FLJ37290 | JAE | dJ304B14.2EF-hand domain (C-terminal) containing 1-HPRD,BioGRID15258581 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_MAPK_SIGNALING_PATHWAY 267205All SZGR genes in this pathway
KEGG_CALCIUM_SIGNALING_PATHWAY 178134All SZGR genes in this pathway
KEGG_TYPE_II_DIABETES_MELLITUS 4741All SZGR genes in this pathway
ENK_UV_RESPONSE_KERATINOCYTE_UP 530342All SZGR genes in this pathway
HAMAI_APOPTOSIS_VIA_TRAIL_DN 186107All SZGR genes in this pathway
DARWICHE_SKIN_TUMOR_PROMOTER_UP 14296All SZGR genes in this pathway
DARWICHE_PAPILLOMA_RISK_LOW_UP 162104All SZGR genes in this pathway
DARWICHE_PAPILLOMA_RISK_HIGH_UP 147101All SZGR genes in this pathway
DARWICHE_SQUAMOUS_CELL_CARCINOMA_UP 146104All SZGR genes in this pathway
SCHLOSSER_SERUM_RESPONSE_DN 712443All SZGR genes in this pathway
SHETH_LIVER_CANCER_VS_TXNIP_LOSS_PAM4 261153All SZGR genes in this pathway
PUJANA_BRCA1_PCC_NETWORK 16521023All SZGR genes in this pathway
BENPORATH_SUZ12_TARGETS 1038678All SZGR genes in this pathway
BENPORATH_EED_TARGETS 1062725All SZGR genes in this pathway
BENPORATH_ES_WITH_H3K27ME3 1118744All SZGR genes in this pathway
BENPORATH_PRC2_TARGETS 652441All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_16HR_DN 8662All SZGR genes in this pathway
RAMASWAMY_METASTASIS_DN 6147All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_14HR_DN 298200All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_48HR_DN 504323All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_12HR_DN 10164All SZGR genes in this pathway
MARZEC_IL2_SIGNALING_DN 3624All SZGR genes in this pathway
MIKKELSEN_IPS_WITH_HCP_H3K27ME3 10276All SZGR genes in this pathway
MIKKELSEN_ES_HCP_WITH_H3K27ME3 4130All SZGR genes in this pathway
MIKKELSEN_MEF_HCP_WITH_H3K27ME3 590403All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_30MIN_DN 15099All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_1HR_DN 222147All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_4HR_DN 254158All SZGR genes in this pathway
WANG_RESPONSE_TO_GSK3_INHIBITOR_SB216763_UP 397206All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
let-7/98136813741Ahsa-let-7abrainUGAGGUAGUAGGUUGUAUAGUU
hsa-let-7bbrainUGAGGUAGUAGGUUGUGUGGUU
hsa-let-7cbrainUGAGGUAGUAGGUUGUAUGGUU
hsa-let-7dbrainAGAGGUAGUAGGUUGCAUAGU
hsa-let-7ebrainUGAGGUAGGAGGUUGUAUAGU
hsa-let-7fbrainUGAGGUAGUAGAUUGUAUAGUU
hsa-miR-98brainUGAGGUAGUAAGUUGUAUUGUU
hsa-let-7gSZUGAGGUAGUAGUUUGUACAGU
hsa-let-7ibrainUGAGGUAGUAGUUUGUGCUGU
miR-1356406471A,m8hsa-miR-135aUAUGGCUUUUUAUUCCUAUGUGA
hsa-miR-135bUAUGGCUUUUCAUUCCUAUGUG
miR-138440446m8hsa-miR-138brainAGCUGGUGUUGUGAAUC
miR-1434934991Ahsa-miR-143brainUGAGAUGAAGCACUGUAGCUCA
miR-182225922651Ahsa-miR-182UUUGGCAAUGGUAGAACUCACA
miR-1832072131Ahsa-miR-183UAUGGCACUGGUAGAAUUCACUG
miR-30-3p193019361Ahsa-miR-30a-3pCUUUCAGUCGGAUGUUUGCAGC
hsa-miR-30e-3pCUUUCAGUCGGAUGUUUACAGC
miR-32023212327m8hsa-miR-320AAAAGCUGGGUUGAGAGGGCGAA
miR-32615001506m8hsa-miR-326CCUCUGGGCCCUUCCUCCAG
miR-96225922651Ahsa-miR-96brainUUUGGCACUAGCACAUUUUUGC
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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