Gene Page: SYN3

Summary
GeneID  8224
Symbol  SYN3
Synonyms  -
Description  synapsin III
See related  HGNC:11496|MIM:602705|Ensembl:ENSG00000185666|HPRD:04083|
Locus tag  LL22NC03-28H9.1
Gene type  protein-coding
Map location  22q12.3
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
AssociationA combined odds ratio method (Sun et al. 2008), association studies1Link to SZGene
GSMA_Igenome scan meta-analysisPsr: 0.031 
LiteratureHigh-throughput literature-searchCo-occurance with Schizophrenia keywords: [schizophrenias, schizophrenia]Click to show detail
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 4 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
TFAP2C0.860.50
DMRTA20.840.49
GPC40.840.52
LRIG30.840.29
COL4A60.800.68
NHLH10.800.49
SOX30.750.58
CELSR10.750.60
JUB0.740.44
ITGA20.730.28
Top 10 negatively co-expressed genes
LGI4-0.23-0.32
SLC16A11-0.21-0.55
SLC9A3R2-0.21-0.49
FBXO2-0.21-0.65
C5orf53-0.21-0.64
ADAP1-0.21-0.41
ASPHD1-0.21-0.57
TMEM54-0.20-0.49
TNFSF12-0.20-0.59
LHPP-0.20-0.57
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0000166nucleotide bindingIEA-
GO:0003824catalytic activityIEA-
GO:0005509calcium ion bindingIEA-
GO:0005524ATP bindingIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0007269neurotransmitter secretionIEAneuron, axon, Synap, serotonin, Neurotransmitter, dopamine (GO term level: 8)-
GO:0007269neurotransmitter secretionTASneuron, axon, Synap, serotonin, Neurotransmitter, dopamine (GO term level: 8)9539796 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0008021synaptic vesicleIEASynap, Neurotransmitter (GO term level: 12)-
GO:0008021synaptic vesicleTASSynap, Neurotransmitter (GO term level: 12)9539796 
GO:0045202synapseIEAneuron, Synap, Neurotransmitter, Glial (GO term level: 2)-
GO:0016020membraneIEA-
GO:0030054cell junctionIEA-
GO:0031410cytoplasmic vesicleIEA-
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
NOS1AP6330408P19Rik | CAPON | MGC138500nitric oxide synthase 1 (neuronal) adaptor protein-HPRD,BioGRID11867766 
SYN1SYN1a | SYN1b | SYNIsynapsin I-HPRD10358015 
SYN2SYNII | SYNIIa | SYNIIbsynapsin II-HPRD,BioGRID10358015 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
REACTOME_TRANSMISSION_ACROSS_CHEMICAL_SYNAPSES 186155All SZGR genes in this pathway
REACTOME_NEURONAL_SYSTEM 279221All SZGR genes in this pathway
REACTOME_NEUROTRANSMITTER_RELEASE_CYCLE 3430All SZGR genes in this pathway
REACTOME_DOPAMINE_NEUROTRANSMITTER_RELEASE_CYCLE 1111All SZGR genes in this pathway
LINDGREN_BLADDER_CANCER_CLUSTER_2B 392251All SZGR genes in this pathway
MANTOVANI_NFKB_TARGETS_UP 4333All SZGR genes in this pathway
MANTOVANI_VIRAL_GPCR_SIGNALING_UP 8654All SZGR genes in this pathway
SATO_SILENCED_BY_METHYLATION_IN_PANCREATIC_CANCER_1 419273All SZGR genes in this pathway
MIKKELSEN_ES_ICP_WITH_H3K4ME3 718401All SZGR genes in this pathway
MIKKELSEN_NPC_ICP_WITH_H3K4ME3 445257All SZGR genes in this pathway
ZWANG_EGF_PERSISTENTLY_DN 6136All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-4524624691A,m8hsa-miR-452UGUUUGCAGAGGAAACUGAGAC
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


Copyright © Bioinformatics and Systems Medicine Laboratory All Rights Reserved since 2009.