Gene Page: TTF2

Summary
GeneID  8458
Symbol  TTF2
Synonyms  HuF2
Description  transcription termination factor, RNA polymerase II
See related  HGNC:12398|MIM:604718|Ensembl:ENSG00000116830|HPRD:05280|
Locus tag  -
Gene type  protein-coding
Map location  1p22
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_Igenome scan meta-analysisPsr: 0.0235 
GSMA_IIAgenome scan meta-analysis (All samples)Psr: 0.00814 
NetworkShortest path distance of core genes in the Human protein-protein interaction networkContribution to shortest path in PPI network: 0.0495 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
Top 10 negatively co-expressed genes
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0000166nucleotide bindingIEA-
GO:0003677DNA bindingIEA-
GO:0003717RNA polymerase II transcription termination factor activityTAS9748214 
GO:0005524ATP bindingIEA-
GO:0016787hydrolase activityIEA-
GO:0008270zinc ion bindingIEA-
GO:0008094DNA-dependent ATPase activityTAS9748214 
GO:0008026ATP-dependent helicase activityIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006353transcription terminationTAS9748214 
GO:0006355regulation of transcription, DNA-dependentIEA-
GO:0006397mRNA processingIEA-
GO:0006350transcriptionIEA-
GO:0008380RNA splicingIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005634nucleusIEA-
GO:0005681spliceosomeIEA-
GO:0005737cytoplasmIEA-
GO:0008023transcription elongation factor complexTAS9748214 
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
CDC5LCEF1 | KIAA0432 | PCDC5RP | dJ319D22.1 | hCDC5CDC5 cell division cycle 5-like (S. pombe)-HPRD,BioGRID12927788 
HuF2 interacts with CDC5L.BIND12927788 
CLPBFLJ13152 | HSP78 | SKD3ClpB caseinolytic peptidase B homolog (E. coli)-HPRD,BioGRID12927788 
DCP1AFLJ21691 | HSA275986 | Nbla00360 | SMAD4IP1 | SMIFDCP1 decapping enzyme homolog A (S. cerevisiae)HuF2 interacts with SMIF TF.BIND12927788 
-HPRD,BioGRID12927788 
DR1NC2 | NC2-BETAdown-regulator of transcription 1, TBP-binding (negative cofactor 2)Two-hybridBioGRID12927788 
DRAP1NC2-alphaDR1-associated protein 1 (negative cofactor 2 alpha)-HPRD,BioGRID12927788 
HuF2 interacts with NC2.BIND12927788 
HNRNPA1HNRPA1 | MGC102835heterogeneous nuclear ribonucleoprotein A1-HPRD12927788 
HNRNPA2B1DKFZp779B0244 | FLJ22720 | HNRNPA2 | HNRNPB1 | HNRPA2 | HNRPA2B1 | HNRPB1 | RNPA2 | SNRPB1heterogeneous nuclear ribonucleoprotein A2/B1-HPRD12927788 
KIF4AFLJ12530 | FLJ12655 | FLJ14204 | FLJ20631 | HSA271784 | KIF4 | KIF4-G1kinesin family member 4A-HPRD12927788 
MATR3DKFZp686K0542 | DKFZp686K23100 | KIAA0723 | MGC9105matrin 3-HPRD12927788 
MYBCmyb | c-myb | c-myb_CDS | efgv-myb myeloblastosis viral oncogene homolog (avian)-HPRD,BioGRID12927788 
MYBL2B-MYB | BMYB | MGC15600v-myb myeloblastosis viral oncogene homolog (avian)-like 2HuF2 interacts with B-myb.BIND12927788 
NVL-nuclear VCP-likeTwo-hybridBioGRID12927788 
PDCD6IPAIP1 | Alix | DRIP4 | HP95 | MGC17003programmed cell death 6 interacting proteinHuF2 interacts with AIP1.BIND12927788 
-HPRD,BioGRID12927788 
PRDX4AOE37-2 | PRX-4peroxiredoxin 4-HPRD,BioGRID12927788 
HuF2 interacts with Peroxiredoxin 4.BIND12927788 
TACC3ERIC1 | MGC117382 | MGC133242transforming, acidic coiled-coil containing protein 3HuF2 interacts with TACC3.BIND12927788 
-HPRD,BioGRID12927788 
TNIP1ABIN-1 | KIAA0113 | NAF1 | VANTNFAIP3 interacting protein 1Two-hybridBioGRID12927788 
HuF2 interacts with NAF1.BIND12927788 
 


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