Gene Page

Gene Page: TTBK1

Summary

GeneID

84630

Symbol

TTBK1

Synonyms

BDTK|KIAA1855|RP3-330M21.4

Description

tau tubulin kinase 1

Locus tag

Gene type

protein-coding

Map location

6p21.1

Gene in Data Sources

Gene set name

Method of gene set

Evidence

Info

GSMA_IIE

genome scan meta-analysis (European-ancestry samples)

Psr: 0.04433

Literature

High-throughput literature-search

Co-occurance with Schizophrenia keywords: [schizophrenias, schizophrenia]

Click to show detail

General Gene Expression (microarray) ?

Gene Expression in Brain Regions (new)

Top co-expressed genes in Brain Regions (new)

Gene

Pearson's Correlation

Spearman's Correlation

Top 10 positively co-expressed genes

Top 10 negatively co-expressed genes

Gene Ontology

Molecular function

GO term

Evidence

Neuro keywords

PubMed ID

GO:0000166

nucleotide binding

IEA

GO:0005524

ATP binding

IEA

GO:0004674

protein serine/threonine kinase activity

IEA

GO:0016740

transferase activity

IEA

Biological process

GO term

Evidence

Neuro keywords

PubMed ID

GO:0006468

protein amino acid phosphorylation

IEA

Cellular component

GO term

Evidence

Neuro keywords

PubMed ID

GO:0005737

cytoplasm

IEA

Protein-protein Interactions

Shown by network

Interactors	Aliases B	Official full name B	Experimental	Source	PubMed ID
CDK5R1	CDK5P35 \| CDK5R \| MGC33831 \| NCK5A \| p23 \| p25 \| p35 \| p35nck5a	cyclin-dependent kinase 5, regulatory subunit 1 (p35)	-	HPRD	7556643
CSN1S1	CASA \| CSN1 \| MGC149368	casein alpha s1	-	HPRD	7556643
GABARAPL2	ATG8 \| GATE-16 \| GATE16 \| GEF-2 \| GEF2	GABA(A) receptor-associated protein-like 2	Affinity Capture-MS	BioGRID	17353931
HEATR1	BAP28 \| FLJ10359 \| MGC72083	HEAT repeat containing 1	Affinity Capture-MS	BioGRID	17353931
MAP2	DKFZp686I2148 \| MAP2A \| MAP2B \| MAP2C	microtubule-associated protein 2	-	HPRD	7556643
NUP205	C7orf14	nucleoporin 205kDa	Affinity Capture-MS	BioGRID	17353931
TTBK2	KIAA0847 \| SCA11 \| TTBK	tau tubulin kinase 2	Affinity Capture-MS	BioGRID	17353931

Pathway annotation

miRNA Targets ?

miRNA family	Target position			miRNA ID	miRNA seq
miRNA family	UTR start	UTR end	Match method	miRNA ID	miRNA seq
miR-133	2038	2044	1A	hsa-miR-133a	UUGGUCCCCUUCAACCAGCUGU
				hsa-miR-133b	UUGGUCCCCUUCAACCAGCUA
				hsa-miR-133a	UUGGUCCCCUUCAACCAGCUGU
				hsa-miR-133b	UUGGUCCCCUUCAACCAGCUA
miR-134	2750	2756	m8	hsa-miR-134^brain	UGUGACUGGUUGACCAGAGGG
miR-181	2721	2727	1A	hsa-miR-181a^brain	AACAUUCAACGCUGUCGGUGAGU
				hsa-miR-181b^SZ	AACAUUCAUUGCUGUCGGUGGG
				hsa-miR-181c^brain	AACAUUCAACCUGUCGGUGAGU
				hsa-miR-181d^brain	AACAUUCAUUGUUGUCGGUGGGUU
miR-204/211	2840	2846	1A	hsa-miR-204^brain	UUCCCUUUGUCAUCCUAUGCCU
miR-204/211	2840	2846	1A	hsa-miR-211	UUCCCUUUGUCAUCCUUCGCCU
miR-219	1919	1926	1A,m8	hsa-miR-219^brain	UGAUUGUCCAAACGCAAUUCU
miR-30-5p	2704	2711	1A,m8	hsa-miR-30a-5p	UGUAAACAUCCUCGACUGGAAG
				hsa-miR-30c^brain	UGUAAACAUCCUACACUCUCAGC
				hsa-miR-30d^SZ	UGUAAACAUCCCCGACUGGAAG
				hsa-miR-30b^SZ	UGUAAACAUCCUACACUCAGCU
				hsa-miR-30e-5p	UGUAAACAUCCUUGACUGGA
miR-31	1985	1991	1A	hsa-miR-31	AGGCAAGAUGCUGGCAUAGCUG
miR-378	1790	1796	1A	hsa-miR-378	CUCCUGACUCCAGGUCCUGUGU
miR-378	1790	1796	1A	hsa-miR-378	CUCCUGACUCCAGGUCCUGUGU
miR-485-5p	481	488	1A,m8	hsa-miR-485-5p	AGAGGCUGGCCGUGAUGAAUUC
miR-543	2701	2707	m8	hsa-miR-543	AAACAUUCGCGGUGCACUUCU

SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.