Gene Page: SUPT3H

Summary
GeneID  8464
Symbol  SUPT3H
Synonyms  SPT3|SPT3L
Description  suppressor of Ty 3 homolog (S. cerevisiae)
See related  HGNC:11466|MIM:602947|Ensembl:ENSG00000196284|HPRD:04254|
Locus tag  RP11-169I2.1
Gene type  protein-coding
Map location  6p21.1-p21.3
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_IIEgenome scan meta-analysis (European-ancestry samples)Psr: 0.04433 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
FCN10.600.48
S100A120.600.51
S100A90.590.60
NKG70.590.57
S100A80.570.57
CD480.550.52
IGHV3-60.530.56
IFITM20.530.59
C16orf140.510.47
LTB0.510.51
Top 10 negatively co-expressed genes
STX6-0.46-0.56
GRLF1-0.46-0.52
HERC1-0.46-0.54
JAKMIP2-0.45-0.55
HNRNPUL2-0.45-0.48
MYO18A-0.45-0.49
CLIP1-0.44-0.50
TP53BP1-0.44-0.55
ERCC6-0.44-0.47
C14orf102-0.44-0.48
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0003677DNA bindingIEA-
GO:0003702RNA polymerase II transcription factor activityIEA-
GO:0003702RNA polymerase II transcription factor activityTAS9787080 
GO:0016986transcription initiation factor activityNAS-
GO:0016563transcription activator activityNAS9787080 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006357regulation of transcription from RNA polymerase II promoterTAS9787080 
GO:0006350transcriptionIEA-
GO:0006366transcription from RNA polymerase II promoterIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005634nucleusIDA9726987 
GO:0005667transcription factor complexIEA-
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
KAT2AGCN5 | GCN5L2 | MGC102791 | PCAF-b | hGCN5K(lysine) acetyltransferase 2AAffinity Capture-WesternBioGRID11406595 
KAT2BCAF | P | P/CAF | PCAFK(lysine) acetyltransferase 2BAffinity Capture-WesternBioGRID12660246 
MYCbHLHe39 | c-Mycv-myc myelocytomatosis viral oncogene homolog (avian)-HPRD,BioGRID12660246 
SAP130FLJ12761Sin3A-associated protein, 130kDaAffinity Capture-WesternBioGRID11406595 
SF3B3KIAA0017 | RSE1 | SAP130 | SF3b130 | STAF130splicing factor 3b, subunit 3, 130kDa-HPRD11406595 
TAF10TAF2A | TAF2H | TAFII30TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDaAffinity Capture-WesternBioGRID11406595 
TAF4FLJ41943 | TAF2C | TAF2C1 | TAF4A | TAFII130 | TAFII135TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDaAffinity Capture-WesternBioGRID11406595 
TAF5TAF2D | TAFII100TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 100kDaAffinity Capture-WesternBioGRID11406595 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
PID_MYC_ACTIV_PATHWAY 7962All SZGR genes in this pathway
PID_MYC_PATHWAY 2522All SZGR genes in this pathway
ZHONG_RESPONSE_TO_AZACITIDINE_AND_TSA_DN 7038All SZGR genes in this pathway
DAVICIONI_TARGETS_OF_PAX_FOXO1_FUSIONS_UP 255177All SZGR genes in this pathway
NAGY_TFTC_COMPONENTS_HUMAN 1911All SZGR genes in this pathway
NAGY_STAGA_COMPONENTS_HUMAN 158All SZGR genes in this pathway
NAGY_PCAF_COMPONENTS_HUMAN 97All SZGR genes in this pathway
NUYTTEN_NIPP1_TARGETS_UP 769437All SZGR genes in this pathway
MASSARWEH_TAMOXIFEN_RESISTANCE_DN 258160All SZGR genes in this pathway
MUELLER_PLURINET 299189All SZGR genes in this pathway
BEIER_GLIOMA_STEM_CELL_DN 6642All SZGR genes in this pathway
CAIRO_HEPATOBLASTOMA_CLASSES_UP 605377All SZGR genes in this pathway
WAKABAYASHI_ADIPOGENESIS_PPARG_BOUND_8D 658397All SZGR genes in this pathway
PEDRIOLI_MIR31_TARGETS_DN 418245All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-30-5p177183m8hsa-miR-30a-5pUGUAAACAUCCUCGACUGGAAG
hsa-miR-30cbrainUGUAAACAUCCUACACUCUCAGC
hsa-miR-30dSZUGUAAACAUCCCCGACUGGAAG
hsa-miR-30bSZUGUAAACAUCCUACACUCAGCU
hsa-miR-30e-5pUGUAAACAUCCUUGACUGGA
miR-3759059111Ahsa-miR-375UUUGUUCGUUCGGCUCGCGUGA
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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