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Association Linkage Expression Literature GO_Annotation Gene Network miRNA Targets

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Association Linkage Expression Literature GO_Annotation Gene Network miRNA Targets Datasets Gene Ranking

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Gene Page: PPFIA4

Summary

GeneID

8497

Symbol

PPFIA4

Synonyms

Description

protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4

Locus tag

Gene type

protein-coding

Map location

1q32.1

Gene in Data Sources

Gene set name

Method of gene set

Evidence

Info

Literature

High-throughput literature-search

Co-occurance with Schizophrenia keywords: [schizophrenias, schizophrenia]

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General Gene Expression (microarray) ?

Gene Expression in Brain Regions (new)

Top co-expressed genes in Brain Regions (new)

Gene

Pearson's Correlation

Spearman's Correlation

Top 10 positively co-expressed genes

C1orf174

0.88

EIF2B5

0.86

DDX56

0.86

EXOSC2

0.86

NRBP1

0.85

MARS

0.85

0.84

NOP56

0.85

0.84

KAT5

0.85

0.87

HDAC3

0.85

0.87

RNPS1

0.84

0.86

Top 10 negatively co-expressed genes

AF347015.31

-0.83

-0.81

MT-CO2

-0.81

-0.79

AF347015.27

-0.80

-0.81

MT-CYB

-0.80

AF347015.8

-0.80

AF347015.33

-0.79

-0.78

AF347015.2

-0.78

AF347015.15

-0.78

-0.79

AF347015.21

-0.77

-0.81

AF347015.26

-0.74

-0.77

Gene Ontology

Molecular function

GO term

Evidence

Neuro keywords

PubMed ID

GO:0005515

protein binding

IPI

12923177

Biological process

GO term

Evidence

Neuro keywords

PubMed ID

GO:0007154

cell communication

NAS

Cellular component

GO term

Evidence

Neuro keywords

PubMed ID

GO:0005622

intracellular

TAS

9624153

GO:0005737

cytoplasm

IEA

GO:0009986

cell surface

IEA

Interactions

Shown by Network

Interactors	Aliases B	Official full name B	Experimental	Source	PubMed ID
DISC1	C1orf136 \| FLJ13381 \| FLJ21640 \| FLJ25311 \| FLJ41105 \| KIAA0457 \| SCZD9	disrupted in schizophrenia 1	An unspecified isoform of DISC1 interacts with PPFIA4.	BIND	14623284
ERC2	CAST \| CAST1 \| ELKSL \| KIAA0378 \| MGC133063 \| MGC133064 \| SPBC110 \| Spc110	ELKS/RAB6-interacting/CAST family member 2	Liprin-alpha4 interacts with ERC2.	BIND	12923177
ERC2		ELKS/RAB6-interacting/CAST family member 2	-	HPRD,BioGRID	12923177
GIT1	-	G protein-coupled receptor kinase interacting ArfGAP 1	-	HPRD,BioGRID	12629171 \|12923177
GIT1	-	G protein-coupled receptor kinase interacting ArfGAP 1	Liprin-alpha4 interacts with GIT1. This interaction was modeled on a demonstrated interaction between human Liprin-alpha4 and rat GIT1.	BIND	12923177
NCOA2	GRIP1 \| KAT13C \| MGC138808 \| NCoA-2 \| TIF2	nuclear receptor coactivator 2	Reconstituted Complex Two-hybrid	BioGRID	11931740

miRNA Targets ?

miRNA family	Target position			miRNA ID	miRNA seq
miRNA family	UTR start	UTR end	Match method	miRNA ID	miRNA seq
miR-101	2240	2247	1A,m8	hsa-miR-101	UACAGUACUGUGAUAACUGAAG
miR-144	2241	2247	1A	hsa-miR-144	UACAGUAUAGAUGAUGUACUAG
miR-342	2293	2299	m8	hsa-miR-342^brain	UCUCACACAGAAAUCGCACCCGUC

SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.