Gene Page: EIF3G

Summary
GeneID  8666
Symbol  EIF3G
Synonyms  EIF3-P42|EIF3S4|eIF3-delta|eIF3-p44
Description  eukaryotic translation initiation factor 3, subunit G
See related  HGNC:3274|MIM:603913|Ensembl:ENSG00000130811|HPRD:04886|
Locus tag  -
Gene type  protein-coding
Map location  19p13.2
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
LiteratureHigh-throughput literature-searchCo-occurance with Schizophrenia keywords: [schizophrenias, schizophrenia]Click to show detail
NetworkShortest path distance of core genes in the Human protein-protein interaction networkContribution to shortest path in PPI network: 0.0018 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
NEK90.820.82
PKD20.790.79
ADAM170.780.75
TBC1D2B0.780.78
GOLGA10.780.79
IKBKB0.770.79
POFUT20.770.75
CAPN20.760.79
FUBP30.760.74
YES10.750.73
Top 10 negatively co-expressed genes
MYL3-0.49-0.50
AF347015.21-0.49-0.53
IFI27-0.47-0.46
AF347015.31-0.46-0.49
AC044839.2-0.46-0.49
RERGL-0.46-0.50
CCDC85B-0.46-0.49
NENF-0.45-0.53
AF347015.27-0.45-0.46
COX5B-0.45-0.49
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0000166nucleotide bindingIEA-
GO:0003723RNA bindingIEA-
GO:0003743translation initiation factor activityIEA-
GO:0005515protein bindingIPI14688252 |15231747 |17353931 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006446regulation of translational initiationTAS9973622 
GO:0006412translationIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005829cytosolEXP12588972 
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
EIF1BGC20eukaryotic translation initiation factor 1BAffinity Capture-MSBioGRID17353931 
EIF3AEIF3 | EIF3S10 | KIAA0139 | P167 | TIF32 | eIF3-p170 | eIF3-theta | p180 | p185eukaryotic translation initiation factor 3, subunit A-HPRD,BioGRID9822659 
EIF3CEIF3S8 | FLJ78287 | MGC189744 | eIF3-p110eukaryotic translation initiation factor 3, subunit C-HPRD,BioGRID9822659 
EIF3DEIF3S7 | MGC126526 | MGC17258 | eIF3-p66 | eIF3-zetaeukaryotic translation initiation factor 3, subunit D-HPRD,BioGRID9822659 
EIF3HEIF3S3 | MGC102958 | eIF3-gamma | eIF3-p40eukaryotic translation initiation factor 3, subunit H-HPRD,BioGRID9822659 
EIF3KARG134 | EIF3-p28 | EIF3S12 | HSPC029 | M9 | MSTP001 | PLAC-24 | PLAC24 | PRO1474 | PTD001eukaryotic translation initiation factor 3, subunit K-HPRD,BioGRID14519125 
EIF5EIF-5Aeukaryotic translation initiation factor 5-HPRD,BioGRID9973622 
EPB414.1R | EL1 | HEerythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked)-HPRD,BioGRID10887144 
MPHOSPH6MPP | MPP-6 | MPP6M-phase phosphoprotein 6-HPRD15231747 
MPP6PALS2 | VAM-1 | VAM1 | p55Tmembrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)-HPRD,BioGRID15231747 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
REACTOME_TRANSLATION 22275All SZGR genes in this pathway
REACTOME_FORMATION_OF_THE_TERNARY_COMPLEX_AND_SUBSEQUENTLY_THE_43S_COMPLEX 7424All SZGR genes in this pathway
REACTOME_ACTIVATION_OF_THE_MRNA_UPON_BINDING_OF_THE_CAP_BINDING_COMPLEX_AND_EIFS_AND_SUBSEQUENT_BINDING_TO_43S 8430All SZGR genes in this pathway
REACTOME_METABOLISM_OF_PROTEINS 518242All SZGR genes in this pathway
REACTOME_3_UTR_MEDIATED_TRANSLATIONAL_REGULATION 17651All SZGR genes in this pathway
ONKEN_UVEAL_MELANOMA_DN 526357All SZGR genes in this pathway
ENK_UV_RESPONSE_KERATINOCYTE_UP 530342All SZGR genes in this pathway
LUI_THYROID_CANCER_CLUSTER_3 2816All SZGR genes in this pathway
LUI_TARGETS_OF_PAX8_PPARG_FUSION 3423All SZGR genes in this pathway
DAIRKEE_TERT_TARGETS_UP 380213All SZGR genes in this pathway
ZUCCHI_METASTASIS_DN 4429All SZGR genes in this pathway
MOREAUX_B_LYMPHOCYTE_MATURATION_BY_TACI_DN 7345All SZGR genes in this pathway
MOREAUX_MULTIPLE_MYELOMA_BY_TACI_DN 172107All SZGR genes in this pathway
IVANOVA_HEMATOPOIESIS_EARLY_PROGENITOR 532309All SZGR genes in this pathway
JIANG_VHL_TARGETS 13891All SZGR genes in this pathway
WANG_CISPLATIN_RESPONSE_AND_XPC_DN 228146All SZGR genes in this pathway
DAZARD_RESPONSE_TO_UV_NHEK_UP 244151All SZGR genes in this pathway
MARSON_BOUND_BY_E2F4_UNSTIMULATED 728415All SZGR genes in this pathway
GRADE_COLON_CANCER_UP 871505All SZGR genes in this pathway
CHNG_MULTIPLE_MYELOMA_HYPERPLOID_UP 5225All SZGR genes in this pathway
WANG_TUMOR_INVASIVENESS_DN 210128All SZGR genes in this pathway
YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_10 6938All SZGR genes in this pathway
DAZARD_UV_RESPONSE_CLUSTER_G5 128All SZGR genes in this pathway
MARTENS_TRETINOIN_RESPONSE_DN 841431All SZGR genes in this pathway
KIM_ALL_DISORDERS_OLIGODENDROCYTE_NUMBER_CORR_UP 756494All SZGR genes in this pathway
KIM_BIPOLAR_DISORDER_OLIGODENDROCYTE_DENSITY_CORR_UP 682440All SZGR genes in this pathway
KIM_ALL_DISORDERS_DURATION_CORR_DN 14690All SZGR genes in this pathway
LI_DCP2_BOUND_MRNA 8957All SZGR genes in this pathway
BRUINS_UVC_RESPONSE_VIA_TP53_GROUP_C 9260All SZGR genes in this pathway


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