Gene Page

Gene Page: VAMP8

Summary

GeneID

8673

Symbol

VAMP8

Synonyms

EDB

Description

vesicle-associated membrane protein 8 (endobrevin)

Locus tag

Gene type

protein-coding

Map location

2p12-p11.2

Gene in Data Sources

Gene set name

Method of gene set

Evidence

Info

GSMA_I

genome scan meta-analysis

Psr: 0.0004

General Gene Expression (microarray) ?

Gene Expression in Brain Regions (new)

Top co-expressed genes in Brain Regions (new)

Gene

Pearson's Correlation

Spearman's Correlation

Top 10 positively co-expressed genes

C6orf154

0.76

0.81

WNT10B

0.76

0.82

SYNGR3

0.75

0.82

ATP6V0C

0.74

0.80

SEZ6L2

0.74

0.77

B3GNT4

0.73

0.75

CCDC3

0.73

0.77

PIM2

0.72

0.81

MAP1LC3A

0.72

0.80

CHAC1

0.70

0.73

Top 10 negatively co-expressed genes

EIF5B

-0.40

-0.47

NSBP1

-0.39

-0.41

AF347015.18

-0.36

-0.24

ANP32B

-0.35

-0.42

ANP32C

-0.35

-0.39

AC005921.3

-0.35

-0.50

AF347015.21

-0.34

-0.16

CWF19L2

-0.34

-0.39

RAB13

-0.34

-0.43

BAZ1A

-0.34

-0.46

Gene Ontology

Molecular function

GO term

Evidence

Neuro keywords

PubMed ID

GO:0005515

protein binding

IEA

Biological process

GO term

Evidence

Neuro keywords

PubMed ID

GO:0016192

vesicle-mediated transport

IEA

Cellular component

GO term

Evidence

Neuro keywords

PubMed ID

GO:0005624

membrane fraction

TAS

9614193

GO:0005769

early endosome

TAS

9614193

GO:0016020

membrane

IEA

GO:0016021

integral to membrane

IEA

Protein-protein Interactions

Shown by network

Interactors	Aliases B	Official full name B	Experimental	Source	PubMed ID
NAPA	SNAPA	N-ethylmaleimide-sensitive factor attachment protein, alpha	-	HPRD,BioGRID	9614193
SNAP23	HsT17016 \| SNAP23A \| SNAP23B	synaptosomal-associated protein, 23kDa	Affinity Capture-Western	BioGRID	10820264 \|12828989
SNAP23	HsT17016 \| SNAP23A \| SNAP23B	synaptosomal-associated protein, 23kDa	-	HPRD	10820264 \|12130530 \|12828989
SNAP25	FLJ23079 \| RIC-4 \| RIC4 \| SEC9 \| SNAP \| SNAP-25 \| bA416N4.2 \| dJ1068F16.2	synaptosomal-associated protein, 25kDa	-	HPRD	10336434
STX1A	HPC-1 \| STX1 \| p35-1	syntaxin 1A (brain)	-	HPRD,BioGRID	11112705
STX1B	STX1B1 \| STX1B2	syntaxin 1B	-	HPRD	11112705
STX2	EPIM \| EPM \| MGC51014 \| STX2A \| STX2B \| STX2C	syntaxin 2	Affinity Capture-Western	BioGRID	12828989
STX3	STX3A	syntaxin 3	-	HPRD	10336434
STX4	STX4A \| p35-2	syntaxin 4	-	HPRD,BioGRID	10820264
STX6	-	syntaxin 6	Affinity Capture-Western	BioGRID	11839770
STX7	-	syntaxin 7	-	HPRD,BioGRID	11278762
STX8	CARB	syntaxin 8	Affinity Capture-Western Co-purification	BioGRID	11101518
VAMP2	FLJ11460 \| SYB2 \| VAMP-2	vesicle-associated membrane protein 2 (synaptobrevin 2)	Reconstituted Complex	BioGRID	12130530
VAMP3	CEB	vesicle-associated membrane protein 3 (cellubrevin)	Reconstituted Complex	BioGRID	12130530
VTI1A	MVti1 \| Vti1-rp2	vesicle transport through interaction with t-SNAREs homolog 1A (yeast)	Affinity Capture-Western Co-purification	BioGRID	11101518

miRNA Targets ?

miRNA family	Target position			miRNA ID	miRNA seq
miRNA family	UTR start	UTR end	Match method	miRNA ID	miRNA seq
miR-15/16/195/424/497	99	105	m8	hsa-miR-15a^brain	UAGCAGCACAUAAUGGUUUGUG
				hsa-miR-16^brain	UAGCAGCACGUAAAUAUUGGCG
				hsa-miR-15b^brain	UAGCAGCACAUCAUGGUUUACA
				hsa-miR-195^SZ	UAGCAGCACAGAAAUAUUGGC
				hsa-miR-424	CAGCAGCAAUUCAUGUUUUGAA
				hsa-miR-497	CAGCAGCACACUGUGGUUUGU
miR-96	58	64	m8	hsa-miR-96^brain	UUUGGCACUAGCACAUUUUUGC

SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.