Gene Page: BECN1

Summary
GeneID  8678
Symbol  BECN1
Synonyms  ATG6|VPS30|beclin1
Description  beclin 1, autophagy related
See related  HGNC:1034|MIM:604378|Ensembl:ENSG00000126581|HPRD:05087|
Locus tag  -
Gene type  protein-coding
Map location  17q21
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
ExpressionExpressionP value: 1.759 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
Top 10 negatively co-expressed genes
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005515protein bindingIPI17589504 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006968cellular defense responseTAS9765397 
GO:0009615response to virusIEA-
GO:0006916anti-apoptosisTAS9765397 
GO:0006914autophagyIEA-
GO:0016239positive regulation of macroautophagyIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0000139Golgi membraneIEA-
GO:0005794Golgi apparatusIEA-
GO:0005802trans-Golgi networkIEA-
GO:0005737cytoplasmIEA-
GO:0016020membraneIEA-
GO:0016023cytoplasmic membrane-bounded vesicleIEA-
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
BCL2Bcl-2B-cell CLL/lymphoma 2-HPRD,BioGRID9765397 
BCL2L1BCL-XL/S | BCL2L | BCLX | Bcl-X | DKFZp781P2092 | bcl-xL | bcl-xSBCL2-like 1-HPRD,BioGRID9765397 
GOPCCAL | FIG | GOPC1 | PIST | dJ94G16.2golgi associated PDZ and coiled-coil motif containing-HPRD,BioGRID12372286 
XPO1CRM1 | DKFZp686B1823exportin 1 (CRM1 homolog, yeast)-HPRD11309306 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_REGULATION_OF_AUTOPHAGY 3530All SZGR genes in this pathway
DIAZ_CHRONIC_MEYLOGENOUS_LEUKEMIA_UP 1382904All SZGR genes in this pathway
KIM_WT1_TARGETS_DN 459276All SZGR genes in this pathway
GRAESSMANN_APOPTOSIS_BY_SERUM_DEPRIVATION_UP 552347All SZGR genes in this pathway
GRAESSMANN_APOPTOSIS_BY_DOXORUBICIN_UP 1142669All SZGR genes in this pathway
MISSIAGLIA_REGULATED_BY_METHYLATION_UP 12678All SZGR genes in this pathway
SCHLOSSER_SERUM_RESPONSE_DN 712443All SZGR genes in this pathway
SPIELMAN_LYMPHOBLAST_EUROPEAN_VS_ASIAN_DN 584395All SZGR genes in this pathway
BLALOCK_ALZHEIMERS_DISEASE_DN 1237837All SZGR genes in this pathway
BANDRES_RESPONSE_TO_CARMUSTIN_MGMT_48HR_DN 161105All SZGR genes in this pathway
AGUIRRE_PANCREATIC_CANCER_COPY_NUMBER_UP 298174All SZGR genes in this pathway
HSIAO_HOUSEKEEPING_GENES 389245All SZGR genes in this pathway
KYNG_WERNER_SYNDROM_AND_NORMAL_AGING_DN 225124All SZGR genes in this pathway
YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_11 10368All SZGR genes in this pathway
SASSON_RESPONSE_TO_GONADOTROPHINS_DN 8766All SZGR genes in this pathway
SASSON_RESPONSE_TO_FORSKOLIN_UP 9058All SZGR genes in this pathway
KIM_ALL_DISORDERS_OLIGODENDROCYTE_NUMBER_CORR_UP 756494All SZGR genes in this pathway
PILON_KLF1_TARGETS_UP 504321All SZGR genes in this pathway
IKEDA_MIR30_TARGETS_UP 11687All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-142-5p136142m8hsa-miR-142-5pCAUAAAGUAGAAAGCACUAC
miR-30-5p981051A,m8hsa-miR-30a-5pUGUAAACAUCCUCGACUGGAAG
hsa-miR-30cbrainUGUAAACAUCCUACACUCUCAGC
hsa-miR-30dSZUGUAAACAUCCCCGACUGGAAG
hsa-miR-30bSZUGUAAACAUCCUACACUCAGCU
hsa-miR-30e-5pUGUAAACAUCCUUGACUGGA
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


Copyright © Bioinformatics and Systems Medicine Laboratory All Rights Reserved since 2009.