Gene Page: RAB11A

Summary
GeneID  8766
Symbol  RAB11A
Synonyms  MGC1490|YL8
Description  RAB11A, member RAS oncogene family
See related  HGNC:9760|MIM:605570|Ensembl:ENSG00000103769|HPRD:05715|
Locus tag  -
Gene type  protein-coding
Map location  15q21.3-q22.31
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 1 
NetworkShortest path distance of core genes in the Human protein-protein interaction networkContribution to shortest path in PPI network: 0.8396 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
Top 10 negatively co-expressed genes
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0019905syntaxin bindingNASSynap (GO term level: 5)12145319 
GO:0000166nucleotide bindingIEA-
GO:0003924GTPase activityNAS11163216 
GO:0005524ATP bindingIEA-
GO:0005525GTP bindingIEA-
GO:0005215transporter activityNAS11163216 
GO:0008134transcription factor bindingIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006355regulation of transcription, DNA-dependentIEA-
GO:0007264small GTPase mediated signal transductionIEA-
GO:0015031protein transportIEA-
GO:0048227plasma membrane to endosome transportNAS11163216 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0055038recycling endosome membraneIEA-
GO:0005802trans-Golgi networkIDA15229288 
GO:0005622intracellularIEA-
GO:0005768endosomeIEA-
GO:0005886plasma membraneIEA-
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
GDI2FLJ16452 | FLJ37352 | RABGDIBGDP dissociation inhibitor 2-HPRD,BioGRID10512627 
MYO5BKIAA1119myosin VB-HPRD,BioGRID11408590 |11495908 
RAB11FIP1DKFZp686E2214 | FLJ22524 | FLJ22622 | MGC78448 | NOEL1A | RCP | rab11-FIP1RAB11 family interacting protein 1 (class I)Affinity Capture-MS
in vitro
in vivo
Reconstituted Complex
Two-hybrid		BioGRID11495908 |11786538 
|17353931 
RAB11FIP2KIAA0941 | Rab11-FIP2 | nRip11RAB11 family interacting protein 2 (class I)-HPRD15304524 
-HPRD,BioGRID11495908 |11994279 
RAB11FIP3KIAA0665 | Rab11-FIP3RAB11 family interacting protein 3 (class II)in vitro
Two-hybrid		BioGRID11495908 
-HPRD11481332 
RAB11FIP4FLJ00131 | KIAA1821 | MGC11316 | MGC126566 | RAB11-FIP4RAB11 family interacting protein 4 (class II)-HPRD,BioGRID12470645 
RAB11FIP5DKFZp434H018 | GAF1 | KIAA0857 | RIP11 | pp75RAB11 family interacting protein 5 (class I)Rab11 interacts with the carboxy terminus, including the coiled-coil region, of Gaf-1.BIND12554740 
Affinity Capture-Western
in vitro
in vivo
Reconstituted Complex
Two-hybrid		BioGRID11163216 |11495908 
RAB3IL1GRABRAB3A interacting protein (rabin3)-like 1Two-hybridBioGRID16189514 
SEC13D3S1231E | SEC13L1 | SEC13R | npp-20SEC13 homolog (S. cerevisiae)Two-hybridBioGRID10747849 
STX4STX4A | p35-2syntaxin 4-HPRD12435603 
WDR44DKFZp686L20145 | MGC26781 | RAB11BP | RPH11WD repeat domain 44-HPRD,BioGRID10077598 |10464283 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_ENDOCYTOSIS 183132All SZGR genes in this pathway
KEGG_VASOPRESSIN_REGULATED_WATER_REABSORPTION 4430All SZGR genes in this pathway
BIOCARTA_RAB_PATHWAY 128All SZGR genes in this pathway
PID_NOTCH_PATHWAY 5949All SZGR genes in this pathway
PID_TXA2PATHWAY 5743All SZGR genes in this pathway
PID_ARF6_DOWNSTREAM_PATHWAY 1514All SZGR genes in this pathway
PID_IL8_CXCR2_PATHWAY 3426All SZGR genes in this pathway
REACTOME_TRANSMEMBRANE_TRANSPORT_OF_SMALL_MOLECULES 413270All SZGR genes in this pathway
REACTOME_AQUAPORIN_MEDIATED_TRANSPORT 5134All SZGR genes in this pathway
REACTOME_REGULATION_OF_WATER_BALANCE_BY_RENAL_AQUAPORINS 4430All SZGR genes in this pathway
NAKAMURA_TUMOR_ZONE_PERIPHERAL_VS_CENTRAL_DN 634384All SZGR genes in this pathway
DIAZ_CHRONIC_MEYLOGENOUS_LEUKEMIA_UP 1382904All SZGR genes in this pathway
GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_RED_DN 2519All SZGR genes in this pathway
MULLIGHAN_NPM1_MUTATED_SIGNATURE_1_DN 12686All SZGR genes in this pathway
MULLIGHAN_MLL_SIGNATURE_2_DN 281186All SZGR genes in this pathway
MULLIGHAN_NPM1_SIGNATURE_3_DN 162116All SZGR genes in this pathway
CHIARADONNA_NEOPLASTIC_TRANSFORMATION_CDC25_UP 12073All SZGR genes in this pathway
BERENJENO_TRANSFORMED_BY_RHOA_DN 394258All SZGR genes in this pathway
OUELLET_CULTURED_OVARIAN_CANCER_INVASIVE_VS_LMP_UP 6940All SZGR genes in this pathway
SEIDEN_MET_SIGNALING 1916All SZGR genes in this pathway
PATIL_LIVER_CANCER 747453All SZGR genes in this pathway
TOMLINS_PROSTATE_CANCER_UP 4027All SZGR genes in this pathway
SCHAEFFER_PROSTATE_DEVELOPMENT_48HR_UP 487286All SZGR genes in this pathway
BENPORATH_MYC_MAX_TARGETS 775494All SZGR genes in this pathway
FLECHNER_PBL_KIDNEY_TRANSPLANT_OK_VS_DONOR_DN 4130All SZGR genes in this pathway
SMITH_TERT_TARGETS_DN 8769All SZGR genes in this pathway
BYSTRYKH_HEMATOPOIESIS_STEM_CELL_QTL_TRANS 882572All SZGR genes in this pathway
FLECHNER_BIOPSY_KIDNEY_TRANSPLANT_OK_VS_DONOR_UP 555346All SZGR genes in this pathway
BLALOCK_ALZHEIMERS_DISEASE_DN 1237837All SZGR genes in this pathway
JIANG_VHL_TARGETS 13891All SZGR genes in this pathway
TAKAO_RESPONSE_TO_UVB_RADIATION_DN 9867All SZGR genes in this pathway
GENTILE_UV_RESPONSE_CLUSTER_D7 4021All SZGR genes in this pathway
GENTILE_UV_HIGH_DOSE_DN 312203All SZGR genes in this pathway
JOSEPH_RESPONSE_TO_SODIUM_BUTYRATE_UP 3121All SZGR genes in this pathway
CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_5 482296All SZGR genes in this pathway
MITSIADES_RESPONSE_TO_APLIDIN_DN 249165All SZGR genes in this pathway
BONOME_OVARIAN_CANCER_SURVIVAL_OPTIMAL_DEBULKING 246152All SZGR genes in this pathway
GOLDRATH_ANTIGEN_RESPONSE 346192All SZGR genes in this pathway
MILI_PSEUDOPODIA_HAPTOTAXIS_UP 518299All SZGR genes in this pathway
KYNG_WERNER_SYNDROM_AND_NORMAL_AGING_UP 9362All SZGR genes in this pathway
DANG_BOUND_BY_MYC 1103714All SZGR genes in this pathway
KIM_ALL_DISORDERS_CALB1_CORR_UP 548370All SZGR genes in this pathway
TORCHIA_TARGETS_OF_EWSR1_FLI1_FUSION_UP 271165All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-124.15175241A,m8hsa-miR-124aUUAAGGCACGCGGUGAAUGCCA
miR-124/5065175231Ahsa-miR-506UAAGGCACCCUUCUGAGUAGA
hsa-miR-124brainUAAGGCACGCGGUGAAUGCC
miR-141/200a8638691Ahsa-miR-141UAACACUGUCUGGUAAAGAUGG
hsa-miR-200aUAACACUGUCUGGUAACGAUGU
miR-142-3p116711731Ahsa-miR-142-3pUGUAGUGUUUCCUACUUUAUGGA
miR-142-5p1461521Ahsa-miR-142-5pCAUAAAGUAGAAAGCACUAC
miR-181226232m8hsa-miR-181abrainAACAUUCAACGCUGUCGGUGAGU
hsa-miR-181bSZAACAUUCAUUGCUGUCGGUGGG
hsa-miR-181cbrainAACAUUCAACCUGUCGGUGAGU
hsa-miR-181dbrainAACAUUCAUUGUUGUCGGUGGGUU
miR-213633701A,m8hsa-miR-21brainUAGCUUAUCAGACUGAUGUUGA
hsa-miR-590GAGCUUAUUCAUAAAAGUGCAG
miR-2165157m8hsa-miR-216UAAUCUCAGCUGGCAACUGUG
miR-263083141Ahsa-miR-26abrainUUCAAGUAAUCCAGGAUAGGC
hsa-miR-26bSZUUCAAGUAAUUCAGGAUAGGUU
miR-30-5p250256m8hsa-miR-30a-5pUGUAAACAUCCUCGACUGGAAG
hsa-miR-30cbrainUGUAAACAUCCUACACUCUCAGC
hsa-miR-30dSZUGUAAACAUCCCCGACUGGAAG
hsa-miR-30bSZUGUAAACAUCCUACACUCAGCU
hsa-miR-30e-5pUGUAAACAUCCUUGACUGGA
miR-542-3p273279m8hsa-miR-542-3pUGUGACAGAUUGAUAACUGAAA
miR-543227233m8hsa-miR-543AAACAUUCGCGGUGCACUUCU
miR-93.hd/291-3p/294/295/302/372/373/520125812651A,m8hsa-miR-93brainAAAGUGCUGUUCGUGCAGGUAG
hsa-miR-302aUAAGUGCUUCCAUGUUUUGGUGA
hsa-miR-302bUAAGUGCUUCCAUGUUUUAGUAG
hsa-miR-302cUAAGUGCUUCCAUGUUUCAGUGG
hsa-miR-302dUAAGUGCUUCCAUGUUUGAGUGU
hsa-miR-372AAAGUGCUGCGACAUUUGAGCGU
hsa-miR-373GAAGUGCUUCGAUUUUGGGGUGU
hsa-miR-520eAAAGUGCUUCCUUUUUGAGGG
hsa-miR-520aAAAGUGCUUCCCUUUGGACUGU
hsa-miR-520bAAAGUGCUUCCUUUUAGAGGG
hsa-miR-520cAAAGUGCUUCCUUUUAGAGGGUU
hsa-miR-520dAAAGUGCUUCUCUUUGGUGGGUU
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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