Gene Page: NAPA

Summary
GeneID  8775
Symbol  NAPA
Synonyms  SNAPA
Description  N-ethylmaleimide-sensitive factor attachment protein, alpha
See related  HGNC:7641|MIM:603215|Ensembl:ENSG00000105402|HPRD:04447|
Locus tag  -
Gene type  protein-coding
Map location  19q13.32
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 3 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
Top 10 negatively co-expressed genes
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0019905syntaxin bindingIEASynap (GO term level: 5)-
GO:0005515protein bindingIPI16189514 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0007420brain developmentIEABrain (GO term level: 7)-
GO:0030182neuron differentiationIEAneuron (GO term level: 8)-
GO:0006944membrane fusionTAS8455721 
GO:0006886intracellular protein transportIEA-
GO:0006891intra-Golgi vesicle-mediated transportTAS8455721 
GO:0016192vesicle-mediated transportIEA-
GO:0045176apical protein localizationIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005794Golgi apparatusIEA-
GO:0005783endoplasmic reticulumIEA-
GO:0016020membraneIEA-
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
GOSR1GOLIM2 | GOS-28 | GOS28 | GOS28/P28 | GS28 | P28golgi SNAP receptor complex member 1-HPRD9325254 
GOSR2Bos1 | GS27golgi SNAP receptor complex member 2-HPRD9349823 
NSFSKD2N-ethylmaleimide-sensitive factor-HPRD,BioGRID9362506 
RTN4ASY | NI220/250 | NOGO | NOGO-A | NOGOC | NSP | NSP-CL | Nbla00271 | Nbla10545 | Nogo-B | Nogo-C | RTN-X | RTN4-A | RTN4-B1 | RTN4-B2 | RTN4-Creticulon 4Two-hybridBioGRID16189514 
SNAP23HsT17016 | SNAP23A | SNAP23Bsynaptosomal-associated protein, 23kDaAffinity Capture-Western
Two-hybrid
BioGRID16189514 
SNAP25FLJ23079 | RIC-4 | RIC4 | SEC9 | SNAP | SNAP-25 | bA416N4.2 | dJ1068F16.2synaptosomal-associated protein, 25kDaReconstituted ComplexBioGRID7622514 
STX12MGC51957 | STX13 | STX14syntaxin 12-HPRD,BioGRID9507000 |9817754 
STX1AHPC-1 | STX1 | p35-1syntaxin 1A (brain)Affinity Capture-Western
Reconstituted Complex
BioGRID7553862 |7622514 
STX4STX4A | p35-2syntaxin 4Affinity Capture-Western
Two-hybrid
BioGRID16189514 
STX5SED5 | STX5Asyntaxin 5Reconstituted Complex
Two-hybrid
BioGRID9506515 |16189514 
STX7-syntaxin 7-HPRD,BioGRID9417091 
STX8CARBsyntaxin 8-HPRD,BioGRID10683148 
TRPC3TRP3transient receptor potential cation channel, subfamily C, member 3TRPC3 interacts with alpha-SNAP.BIND15327778 
-HPRD15327778 
VAMP2FLJ11460 | SYB2 | VAMP-2vesicle-associated membrane protein 2 (synaptobrevin 2)Reconstituted ComplexBioGRID7622514 
VAMP8EDBvesicle-associated membrane protein 8 (endobrevin)-HPRD,BioGRID9614193 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
REACTOME_MEMBRANE_TRAFFICKING 12974All SZGR genes in this pathway
REACTOME_TRANS_GOLGI_NETWORK_VESICLE_BUDDING 6031All SZGR genes in this pathway
REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS 5327All SZGR genes in this pathway
DIAZ_CHRONIC_MEYLOGENOUS_LEUKEMIA_UP 1382904All SZGR genes in this pathway
DEURIG_T_CELL_PROLYMPHOCYTIC_LEUKEMIA_UP 368234All SZGR genes in this pathway
ELVIDGE_HYPOXIA_BY_DMOG_DN 5940All SZGR genes in this pathway
GRAESSMANN_APOPTOSIS_BY_DOXORUBICIN_UP 1142669All SZGR genes in this pathway
GRAESSMANN_RESPONSE_TO_MC_AND_DOXORUBICIN_UP 612367All SZGR genes in this pathway
SPIELMAN_LYMPHOBLAST_EUROPEAN_VS_ASIAN_DN 584395All SZGR genes in this pathway
ASTON_MAJOR_DEPRESSIVE_DISORDER_DN 160110All SZGR genes in this pathway
MODY_HIPPOCAMPUS_POSTNATAL 6350All SZGR genes in this pathway
IVANOVA_HEMATOPOIESIS_LATE_PROGENITOR 544307All SZGR genes in this pathway
LU_AGING_BRAIN_DN 153120All SZGR genes in this pathway
LEE_AGING_CEREBELLUM_DN 8666All SZGR genes in this pathway
LEE_AGING_NEOCORTEX_UP 8959All SZGR genes in this pathway
AGUIRRE_PANCREATIC_CANCER_COPY_NUMBER_UP 298174All SZGR genes in this pathway
KIM_ALL_DISORDERS_CALB1_CORR_UP 548370All SZGR genes in this pathway


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