Gene Page: RGS9

Summary
GeneID  8787
Symbol  RGS9
Synonyms  MGC111763|MGC26458|PERRS|RGS9L
Description  regulator of G-protein signaling 9
See related  HGNC:10004|MIM:604067|Ensembl:ENSG00000108370|HPRD:04962|
Locus tag  -
Gene type  protein-coding
Map location  17q23-q24
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
LiteratureHigh-throughput literature-searchCo-occurance with Schizophrenia keywords: [schizophrenias, schizophrenic, schizophrenia]Click to show detail
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
LMTK20.910.91
AP000751.30.880.88
BSN0.880.89
C17orf510.870.88
KALRN0.870.88
TLN20.870.87
SPRED20.870.89
FMN20.870.88
MEF2D0.860.88
ZC3H12B0.860.86
Top 10 negatively co-expressed genes
DBI-0.52-0.59
C1orf54-0.50-0.62
RHOC-0.50-0.57
GNG11-0.49-0.56
AF347015.21-0.48-0.51
AL139819.3-0.46-0.52
SYCP3-0.45-0.57
C1orf61-0.45-0.52
VAMP5-0.44-0.47
RPS27L-0.44-0.47
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0004871signal transducer activityIEA-
GO:0005096GTPase activator activityTAS9765512 
GO:0005515protein bindingIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0009968negative regulation of signal transductionIEA-
GO:0007242intracellular signaling cascadeIEA-
GO:0008277regulation of G-protein coupled receptor protein signaling pathwayTAS9765512 
GO:0007601visual perceptionIEA-
GO:0050896response to stimulusIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005834heterotrimeric G-protein complexIEA-
GO:0016020membraneIEA-
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
GUCY2DCORD5 | CORD6 | CYGD | GUC1A4 | GUC2D | LCA | LCA1 | RETGC-1 | ROS-GC1 | retGCguanylate cyclase 2D, membrane (retina-specific)-HPRD11485301 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
PID_CONE_PATHWAY 238All SZGR genes in this pathway
PID_RHODOPSIN_PATHWAY 2410All SZGR genes in this pathway
REACTOME_SIGNALING_BY_GPCR 920449All SZGR genes in this pathway
REACTOME_GPCR_DOWNSTREAM_SIGNALING 805368All SZGR genes in this pathway
REACTOME_G_ALPHA_I_SIGNALLING_EVENTS 195114All SZGR genes in this pathway
ZHONG_RESPONSE_TO_AZACITIDINE_AND_TSA_UP 183119All SZGR genes in this pathway
SENESE_HDAC3_TARGETS_DN 536332All SZGR genes in this pathway
BENPORATH_ES_WITH_H3K27ME3 1118744All SZGR genes in this pathway
NIKOLSKY_BREAST_CANCER_17Q21_Q25_AMPLICON 335181All SZGR genes in this pathway
OKUMURA_INFLAMMATORY_RESPONSE_LPS 183115All SZGR genes in this pathway
KUMAR_TARGETS_OF_MLL_AF9_FUSION 405264All SZGR genes in this pathway
BLALOCK_ALZHEIMERS_DISEASE_INCIPIENT_UP 390242All SZGR genes in this pathway
IVANOVA_HEMATOPOIESIS_LATE_PROGENITOR 544307All SZGR genes in this pathway
BLALOCK_ALZHEIMERS_DISEASE_UP 16911088All SZGR genes in this pathway
YOSHIMURA_MAPK8_TARGETS_UP 1305895All SZGR genes in this pathway
RAO_BOUND_BY_SALL4_ISOFORM_A 182108All SZGR genes in this pathway
GHANDHI_DIRECT_IRRADIATION_UP 11068All SZGR genes in this pathway
GHANDHI_BYSTANDER_IRRADIATION_UP 8654All SZGR genes in this pathway
ZWANG_TRANSIENTLY_UP_BY_2ND_EGF_PULSE_ONLY 1725838All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-124.12552621A,m8hsa-miR-124aUUAAGGCACGCGGUGAAUGCCA
miR-124/5062552611Ahsa-miR-506UAAGGCACCCUUCUGAGUAGA
hsa-miR-124brainUAAGGCACGCGGUGAAUGCC
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


Copyright © Bioinformatics and Systems Medicine Laboratory All Rights Reserved since 2009.