Gene Page: STK19

Summary
GeneID  8859
Symbol  STK19
Synonyms  D6S60|D6S60E|G11|HLA-RP1|MGC117388|RP1
Description  serine/threonine kinase 19
See related  HGNC:11398|MIM:604977|Ensembl:ENSG00000204344|HPRD:07281|
Locus tag  DADB-112B14.2
Gene type  protein-coding
Map location  6p21.3
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_Igenome scan meta-analysisPsr: 0.033 
LiteratureHigh-throughput literature-searchCo-occurance with Schizophrenia keywords: [schizophrenias, schizophrenia]Click to show detail
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
CNGB10.720.79
SLC7A40.710.81
MATN20.710.72
GALNTL10.680.76
MYO7A0.670.73
VWA5A0.660.74
TMEM1300.660.78
LENG40.650.79
KCNC40.650.79
AC112484.10.630.73
Top 10 negatively co-expressed genes
SLA-0.250.07
KLHL1-0.250.06
DACT1-0.250.08
RPL24-0.24-0.33
NEUROD6-0.24-0.03
RPS3AP47-0.24-0.29
SATB2-0.230.02
RPL9-0.23-0.30
SCUBE1-0.23-0.18
RPL31-0.23-0.34
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0000166nucleotide bindingIEA-
GO:0005515protein bindingIPI14667819 
GO:0005524ATP bindingIEA-
GO:0004674protein serine/threonine kinase activityTAS9812991 
GO:0016740transferase activityIEA-
GO:0016301kinase activityIEA-
GO:0030145manganese ion bindingIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006468protein amino acid phosphorylationTAS9812991 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005634nucleusTAS9812991 
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
POLEDKFZp434F222 | FLJ21434 | POLE1polymerase (DNA directed), epsilonTwo-hybridBioGRID14667819 
POLR2GMGC138367 | MGC138369 | RPB7 | hRPB19 | hsRPB7polymerase (RNA) II (DNA directed) polypeptide G-HPRD,BioGRID14667819 
PRAMEMAPE | OIP4preferentially expressed antigen in melanomaTwo-hybridBioGRID14667819 
SF3B4MGC10828 | SAP49 | SF3b49splicing factor 3b, subunit 4, 49kDa-HPRD14667819 
SLC29A1ENT1 | MGC1465 | MGC3778solute carrier family 29 (nucleoside transporters), member 1Two-hybridBioGRID14667819 
SP3DKFZp686O1631 | SPR-2Sp3 transcription factor-HPRD,BioGRID14667819 
 
Pathway annotation
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-15/16/195/424/497152158m8hsa-miR-15abrainUAGCAGCACAUAAUGGUUUGUG
hsa-miR-16brainUAGCAGCACGUAAAUAUUGGCG
hsa-miR-15bbrainUAGCAGCACAUCAUGGUUUACA
hsa-miR-195SZUAGCAGCACAGAAAUAUUGGC
hsa-miR-424CAGCAGCAAUUCAUGUUUUGAA
hsa-miR-497CAGCAGCACACUGUGGUUUGU
miR-1823703771A,m8hsa-miR-182UUUGGCAAUGGUAGAACUCACA
miR-963713771Ahsa-miR-96brainUUUGGCACUAGCACAUUUUUGC
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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