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| GeneID |
8892
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| Symbol |
EIF2B2
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| Synonyms |
EIF-2Bbeta|EIF2B
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| Description |
eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa |
| See related |
HGNC:3258|MIM:606454|Ensembl:ENSG00000119718|HPRD:05923| |
| Locus tag |
- |
| Gene type |
protein-coding |
| Map location |
14q24.3 |
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| Gene set name |
Method of gene set |
Evidence |
Info |
| GO_Annotation | Mapping neuro-related keywords to Gene Ontology annotations | Hits with neuro-related keywords: 3 | |
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| General Gene Expression (microarray) ? |
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| Gene Expression in Brain Regions (new) |
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| Top co-expressed genes in Brain Regions (new) |
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| Gene | Pearson's Correlation | Spearman's Correlation | | |
| Top 10 positively co-expressed genes |
| SH3TC1 | 0.62 | 0.35 | | |
| IGFBP1 | 0.59 | 0.27 | | |
| C10orf10 | 0.57 | 0.21 | | |
| EDN1 | 0.56 | 0.13 | | |
| IL4R | 0.56 | 0.39 | | |
| HRCT1 | 0.54 | -0.06 | | |
| TBX1 | 0.51 | 0.26 | | |
| CLDN5 | 0.49 | 0.20 | | |
| TNFRSF12A | 0.48 | 0.25 | | |
| CEBPD | 0.47 | 0.16 | | |
Top 10 negatively co-expressed genes | | HSPA5 | -0.35 | -0.26 | | |
| HDHD2 | -0.35 | -0.21 | | |
| SBDS | -0.35 | -0.25 | | |
| ERGIC2 | -0.34 | -0.23 | | |
| PDHB | -0.34 | -0.22 | | |
| C19orf2 | -0.34 | -0.18 | | |
| PPP2CB | -0.34 | -0.20 | | |
| IARS2 | -0.34 | -0.19 | | |
| AC023598.3 | -0.33 | -0.31 | | |
| PPP2R5A | -0.33 | -0.29 | | |
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| Molecular function | GO term | Evidence | Neuro keywords | PubMed ID |
|---|
| GO:0005085 | guanyl-nucleotide exchange factor activity | IDA | | 11323413 |
| GO:0005085 | guanyl-nucleotide exchange factor activity | IMP | | 15054402 |
| GO:0003743 | translation initiation factor activity | IDA | | 16289705 |
| GO:0005515 | protein binding | IPI | | 15060152 |
| GO:0005524 | ATP binding | IDA | | 11323413 |
| GO:0005525 | GTP binding | IDA | | 11323413 |
| Biological process | GO term | Evidence | Neuro keywords | PubMed ID |
|---|
| GO:0007417 | central nervous system development | IMP | Brain (GO term level: 6) | 15776425 |
| GO:0014003 | oligodendrocyte development | IMP | axon, oligodendrocyte, Glial (GO term level: 10) | 15217090 |
| GO:0042552 | myelination | IMP | neuron, axon, Brain, oligodendrocyte (GO term level: 13) | 14566705 |
| GO:0001541 | ovarian follicle development | IMP | | 15507143 |
| GO:0006446 | regulation of translational initiation | TAS | | 15060152 |
| GO:0009408 | response to heat | ISS | | - |
| GO:0009408 | response to heat | TAS | | 12499492 |
| GO:0009749 | response to glucose stimulus | ISS | | - |
| GO:0043434 | response to peptide hormone stimulus | ISS | | - |
| GO:0044237 | cellular metabolic process | IEA | | - |
| GO:0051716 | cellular response to stimulus | IDA | | 8626696 |
| Cellular component | GO term | Evidence | Neuro keywords | PubMed ID |
|---|
| GO:0005851 | eukaryotic translation initiation factor 2B complex | IDA | | 11323413 |15060152 |
| GO:0005634 | nucleus | IDA | | 18029348 |
| GO:0005730 | nucleolus | IDA | | 18029348 |
| GO:0005737 | cytoplasm | IDA | | 11323413 |
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- SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
- Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.
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