Gene Page: SKAP2

Summary
GeneID  8935
Symbol  SKAP2
Synonyms  MGC10411|MGC33304|PRAP|RA70|SAPS|SCAP2|SKAP-HOM|SKAP55R
Description  src kinase associated phosphoprotein 2
See related  HGNC:15687|MIM:605215|Ensembl:ENSG00000005020|HPRD:05558|
Locus tag  -
Gene type  protein-coding
Map location  7p21-p15
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
NetworkShortest path distance of core genes in the Human protein-protein interaction networkContribution to shortest path in PPI network: 0.0036 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
BUB10.980.66
TPX20.980.86
KIF230.980.81
KIF4A0.980.74
BUB1B0.980.72
NUSAP10.980.66
KIF2C0.980.71
NCAPH0.980.76
MCM100.980.68
CCNA20.980.76
Top 10 negatively co-expressed genes
AF347015.31-0.40-0.77
AF347015.27-0.39-0.73
MT-CO2-0.39-0.76
AF347015.33-0.39-0.71
MT-CYB-0.38-0.73
HLA-F-0.38-0.58
PTH1R-0.38-0.59
C5orf53-0.38-0.55
IFI27-0.37-0.72
FXYD1-0.37-0.72
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005070SH3/SH2 adaptor activityTAS9671755 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006461protein complex assemblyTAS9671755 
GO:0007165signal transductionTAS9837776 
GO:0008285negative regulation of cell proliferationIEA-
GO:0042113B cell activationIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005737cytoplasmIEA-
GO:0005886plasma membraneIDA11390434 
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
FYBADAP | PRO0823 | SLAP-130FYN binding protein (FYB-120/130)-HPRD9671755 
FYNMGC45350 | SLK | SYNFYN oncogene related to SRC, FGR, YES-HPRD,BioGRID9837776 
HCKJTK9hemopoietic cell kinase-HPRD,BioGRID9837776 
LYNFLJ26625 | JTK8v-yes-1 Yamaguchi sarcoma viral related oncogene homolog-HPRD,BioGRID9837776 
PRAM1MGC39864 | PRAM-1PML-RARA regulated adaptor molecule 1-HPRD,BioGRID11301322 
 
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-18220322038m8hsa-miR-182UUUGGCAAUGGUAGAACUCACA
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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