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|
| GeneID |
9177
|
| Symbol |
HTR3B
|
| Synonyms |
5-HT3B
|
| Description |
5-hydroxytryptamine (serotonin) receptor 3B |
| See related |
HGNC:5298|MIM:604654|Ensembl:ENSG00000149305|HPRD:06875| |
| Locus tag |
- |
| Gene type |
protein-coding |
| Map location |
11q23.1 |
|
| |
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|
| Gene set name |
Method of gene set |
Evidence |
Info |
| GSMA_I | genome scan meta-analysis | Psr: 0.006 | | | Expression | Expression | P value: 1.521 | | | Literature | High-throughput literature-search | Co-occurance with Schizophrenia keywords: [schizophrenias, schizophrenia] | Click to show detail | | GO_Annotation | Mapping neuro-related keywords to Gene Ontology annotations | Hits with neuro-related keywords: 6 | |
|
| |
| General Gene Expression (microarray) ? |
|
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| |
| Gene Expression in Brain Regions (new) |
|
| |
| Top co-expressed genes in Brain Regions (new) |
|
| Gene | Pearson's Correlation | Spearman's Correlation | | |
| Top 10 positively co-expressed genes |
| SCNN1D | 0.82 | 0.84 | | |
| C16orf79 | 0.76 | 0.78 | | |
| CPT1B | 0.76 | 0.79 | | |
| DOM3Z | 0.75 | 0.77 | | |
| AP1G2 | 0.75 | 0.83 | | |
| PILRB | 0.75 | 0.79 | | |
| LIME1 | 0.75 | 0.76 | | |
| HSF4 | 0.75 | 0.79 | | |
| NOXA1 | 0.75 | 0.78 | | |
| MAN2C1 | 0.74 | 0.77 | | |
Top 10 negatively co-expressed genes | | ABCD2 | -0.37 | -0.33 | | |
| GMFB | -0.35 | -0.31 | | |
| PNPLA8 | -0.35 | -0.34 | | |
| LMBRD2 | -0.35 | -0.29 | | |
| TTC33 | -0.33 | -0.29 | | |
| HSPA13 | -0.33 | -0.25 | | |
| RAB30 | -0.33 | -0.25 | | |
| MOBKL3 | -0.32 | -0.28 | | |
| RLIM | -0.32 | -0.25 | | |
| AGPS | -0.32 | -0.27 | | |
|
| Molecular function | GO term | Evidence | Neuro keywords | PubMed ID |
|---|
| GO:0030594 | neurotransmitter receptor activity | IEA | Neurotransmitter (GO term level: 5) | - |
| GO:0005232 | serotonin-activated cation-selective channel activity | TAS | serotonin (GO term level: 11) | 9950429 |
| GO:0004993 | serotonin receptor activity | TAS | serotonin, Neurotransmitter (GO term level: 8) | 9950429 |
| GO:0005216 | ion channel activity | TAS | | 9950429 |
| GO:0005230 | extracellular ligand-gated ion channel activity | IEA | | - |
| Biological process | GO term | Evidence | Neuro keywords | PubMed ID |
|---|
| GO:0007268 | synaptic transmission | TAS | neuron, Synap, Neurotransmitter (GO term level: 6) | 9950429 |
| GO:0007210 | serotonin receptor signaling pathway | IEA | serotonin (GO term level: 8) | - |
| GO:0006811 | ion transport | IEA | | - |
| Cellular component | GO term | Evidence | Neuro keywords | PubMed ID |
|---|
| GO:0045211 | postsynaptic membrane | IEA | Synap, Neurotransmitter (GO term level: 5) | - |
| GO:0005886 | plasma membrane | IEA | | - |
| GO:0005887 | integral to plasma membrane | TAS | | 9950429 |
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