Gene Page: CD5

Summary
GeneID  921
Symbol  CD5
Synonyms  LEU1|T1
Description  CD5 molecule
See related  HGNC:1685|MIM:153340|Ensembl:ENSG00000110448|HPRD:01078|
Locus tag  -
Gene type  protein-coding
Map location  11q13
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
NetworkShortest path distance of core genes in the Human protein-protein interaction networkContribution to shortest path in PPI network: 0.0226 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
PODNL10.740.23
KLK100.710.21
EGFL60.670.15
GPR1770.660.04
MAP4K10.660.19
ANXA30.660.36
OTX20.660.11
HSD11B20.660.23
ANO20.650.10
CEACAM210.640.20
Top 10 negatively co-expressed genes
GTDC1-0.31-0.35
EMX1-0.30-0.38
SATB1-0.28-0.36
ARL4D-0.28-0.34
ARHGEF2-0.27-0.32
C1orf96-0.27-0.33
CRYM-0.27-0.32
ZNF238-0.27-0.35
MEF2C-0.26-0.34
LMO7-0.26-0.33
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005044scavenger receptor activityIEA-
GO:0005515protein bindingIPI1711157 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0008283cell proliferationNAS3093892 
GO:0008037cell recognitionNAS1711157 
GO:0008624induction of apoptosis by extracellular signalsIEA-
GO:0031295T cell costimulationIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0009897external side of plasma membraneIEA-
GO:0005886plasma membraneIDA11390434 
GO:0005887integral to plasma membraneNAS1711157 
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
CAMK2DCAMKD | DKFZp686G23119 | DKFZp686I2288 | MGC44911calcium/calmodulin-dependent protein kinase II deltain vitro
Two-hybrid
BioGRID9692886 
CBLC-CBL | CBL2 | RNF55Cas-Br-M (murine) ecotropic retroviral transforming sequence-HPRD,BioGRID9603468 
CD2SRBC | T11CD2 molecule-HPRD,BioGRID10510361 
CD247CD3-ZETA | CD3H | CD3Q | CD3Z | T3Z | TCRZCD247 molecule-HPRD1385158 
CD27MGC20393 | S152 | T14 | TNFRSF7 | Tp55CD27 moleculeReconstituted ComplexBioGRID1711157 
CD4CD4mutCD4 molecule-HPRD7539755 
CD6FLJ44171 | TP120CD6 molecule-HPRD,BioGRID12473675 
CD72CD72b | LYB2CD72 molecule-HPRD1711157 |8806810 
DYNLT3RP3 | TCTE1L | TCTEX1Ldynein, light chain, Tctex-type 3-HPRD,BioGRID9692886 
LCKYT16 | p56lck | pp58lcklymphocyte-specific protein tyrosine kinase-HPRD7513045 
PIK3R1GRB1 | p85 | p85-ALPHAphosphoinositide-3-kinase, regulatory subunit 1 (alpha)-HPRD,BioGRID9079809 
PTPN6HCP | HCPH | HPTP1C | PTP-1C | SH-PTP1 | SHP-1 | SHP-1L | SHP1protein tyrosine phosphatase, non-receptor type 6-HPRD,BioGRID10082557 
RASA1CM-AVM | CMAVM | DKFZp434N071 | GAP | PKWS | RASA | RASGAP | p120GAP | p120RASGAPRAS p21 protein activator (GTPase activating protein) 1-HPRD,BioGRID9603468 
ZAP70FLJ17670 | FLJ17679 | SRK | STD | TZK | ZAP-70zeta-chain (TCR) associated protein kinase 70kDa-HPRD,BioGRID9378960 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_HEMATOPOIETIC_CELL_LINEAGE 8860All SZGR genes in this pathway
BIOCARTA_DC_PATHWAY 2220All SZGR genes in this pathway
HUTTMANN_B_CLL_POOR_SURVIVAL_UP 276187All SZGR genes in this pathway
DOANE_RESPONSE_TO_ANDROGEN_UP 184125All SZGR genes in this pathway
JAATINEN_HEMATOPOIETIC_STEM_CELL_DN 226132All SZGR genes in this pathway
SHANK_TAL1_TARGETS_DN 106All SZGR genes in this pathway
NIKOLSKY_BREAST_CANCER_11Q12_Q14_AMPLICON 15893All SZGR genes in this pathway
BYSTRYKH_HEMATOPOIESIS_STEM_CELL_QTL_TRANS 882572All SZGR genes in this pathway
SANSOM_APC_TARGETS_DN 366238All SZGR genes in this pathway
KUMAR_TARGETS_OF_MLL_AF9_FUSION 405264All SZGR genes in this pathway
ZHOU_TNF_SIGNALING_30MIN 5436All SZGR genes in this pathway
HILLION_HMGA1B_TARGETS 9268All SZGR genes in this pathway
ACEVEDO_METHYLATED_IN_LIVER_CANCER_DN 940425All SZGR genes in this pathway
YOSHIMURA_MAPK8_TARGETS_DN 366257All SZGR genes in this pathway
MARTENS_TRETINOIN_RESPONSE_UP 857456All SZGR genes in this pathway
BOSCO_TH1_CYTOTOXIC_MODULE 11462All SZGR genes in this pathway


Copyright © Bioinformatics and Systems Medicine Laboratory All Rights Reserved since 2009.