Gene Page: CYTH2

Summary
GeneID  9266
Symbol  CYTH2
Synonyms  ARNO|CTS18|CTS18.1|PSCD2|PSCD2L|SEC7L|Sec7p-L|Sec7p-like
Description  cytohesin 2
See related  HGNC:9502|MIM:602488|Ensembl:ENSG00000105443|HPRD:03925|
Locus tag  -
Gene type  protein-coding
Map location  19q13.33
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
NetworkShortest path distance of core genes in the Human protein-protein interaction networkContribution to shortest path in PPI network: 0.0089 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
NPY1R0.740.59
C1orf620.720.59
LMO40.720.55
TAL20.680.57
NPNT0.660.52
RASGEF1C0.650.66
RPRM0.650.63
PTX30.640.57
STK32B0.630.54
PPP1R14C0.630.61
Top 10 negatively co-expressed genes
REEP6-0.43-0.42
TSC22D4-0.39-0.42
AIFM3-0.39-0.42
AF347015.27-0.39-0.49
HLA-F-0.39-0.39
RHBDL3-0.39-0.47
HEPN1-0.38-0.41
RENBP-0.38-0.43
CLU-0.38-0.39
AF347015.33-0.38-0.49
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005086ARF guanyl-nucleotide exchange factor activityIEA-
GO:0005086ARF guanyl-nucleotide exchange factor activityTAS9417041 
GO:0005515protein bindingIPI14654833 |16415858 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006897endocytosisTAS9417041 
GO:0030036actin cytoskeleton organizationTAS9417041 
GO:0032012regulation of ARF protein signal transductionIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005622intracellularIEA-
GO:0005624membrane fractionTAS9417041 
GO:0005886plasma membraneTAS9417041 
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
ARF1-ADP-ribosylation factor 1-HPRD,BioGRID9417041 
ARF6DKFZp564M0264ADP-ribosylation factor 6-HPRD,BioGRID9417041 
ARRB1ARB1 | ARR1arrestin, beta 1-HPRD,BioGRID11533043 
ARRB2ARB2 | ARR2 | BARR2 | DKFZp686L0365arrestin, beta 2-HPRD,BioGRID11533043 
CCDC120JM11coiled-coil domain containing 120Two-hybridBioGRID16189514 
PIP3-EIPCEF1 | KIAA0403 | RP3-402L9.2phosphoinositide-binding protein PIP3-E-HPRD,BioGRID12920129 
SFNYWHASstratifinAffinity Capture-MSBioGRID15778465 
TRIM23ARD1 | ARFD1 | RNF46tripartite motif-containing 23-HPRD,BioGRID10748148 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
BIOCARTA_ARAP_PATHWAY 1813All SZGR genes in this pathway
PID_ARF6_PATHWAY 3527All SZGR genes in this pathway
PID_PI3KCI_PATHWAY 4940All SZGR genes in this pathway
PID_ARF_3PATHWAY 1913All SZGR genes in this pathway
GAZDA_DIAMOND_BLACKFAN_ANEMIA_ERYTHROID_DN 493298All SZGR genes in this pathway
DIAZ_CHRONIC_MEYLOGENOUS_LEUKEMIA_UP 1382904All SZGR genes in this pathway
SENESE_HDAC1_TARGETS_DN 260143All SZGR genes in this pathway
KINSEY_TARGETS_OF_EWSR1_FLII_FUSION_DN 329219All SZGR genes in this pathway
ENK_UV_RESPONSE_KERATINOCYTE_UP 530342All SZGR genes in this pathway
ALCALA_APOPTOSIS 8860All SZGR genes in this pathway
BUYTAERT_PHOTODYNAMIC_THERAPY_STRESS_UP 811508All SZGR genes in this pathway
BENPORATH_MYC_MAX_TARGETS 775494All SZGR genes in this pathway
BENPORATH_CYCLING_GENES 648385All SZGR genes in this pathway
PETRETTO_BLOOD_PRESSURE_DN 76All SZGR genes in this pathway
BYSTRYKH_HEMATOPOIESIS_STEM_CELL_QTL_TRANS 882572All SZGR genes in this pathway
MURAKAMI_UV_RESPONSE_6HR_UP 3731All SZGR genes in this pathway
VERRECCHIA_RESPONSE_TO_TGFB1_C2 2518All SZGR genes in this pathway
VERRECCHIA_EARLY_RESPONSE_TO_TGFB1 5843All SZGR genes in this pathway
BILD_MYC_ONCOGENIC_SIGNATURE 206117All SZGR genes in this pathway
KRIGE_RESPONSE_TO_TOSEDOSTAT_6HR_UP 953554All SZGR genes in this pathway
KRIGE_RESPONSE_TO_TOSEDOSTAT_24HR_UP 783442All SZGR genes in this pathway
DANG_BOUND_BY_MYC 1103714All SZGR genes in this pathway
MURAKAMI_UV_RESPONSE_1HR_DN 108All SZGR genes in this pathway
WHITFIELD_CELL_CYCLE_G2 182102All SZGR genes in this pathway
BAKKER_FOXO3_TARGETS_DN 187109All SZGR genes in this pathway
FEVR_CTNNB1_TARGETS_UP 682433All SZGR genes in this pathway
KRIEG_HYPOXIA_NOT_VIA_KDM3A 770480All SZGR genes in this pathway
ZWANG_DOWN_BY_2ND_EGF_PULSE 293119All SZGR genes in this pathway
ZWANG_TRANSIENTLY_UP_BY_1ST_EGF_PULSE_ONLY 1839928All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-28114120m8hsa-miR-28brainAAGGAGCUCACAGUCUAUUGAG
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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