Gene Page

Gene Page: HOMER3

Summary

GeneID

9454

Symbol

HOMER3

Synonyms

HOMER-3

Description

homer homolog 3 (Drosophila)

Locus tag

Gene type

protein-coding

Map location

19p13.11

Gene in Data Sources

Gene set name

Method of gene set

Evidence

Info

Literature

High-throughput literature-search

Co-occurance with Schizophrenia keywords: [schizophrenias, schizophrenics, schizophrenia]

Click to show detail

GO_Annotation

Mapping neuro-related keywords to Gene Ontology annotations

Hits with neuro-related keywords: 2

General Gene Expression (microarray) ?

Gene Expression in Brain Regions (new)

Top co-expressed genes in Brain Regions (new)

Gene

Pearson's Correlation

Spearman's Correlation

Top 10 positively co-expressed genes

Top 10 negatively co-expressed genes

Gene Ontology

Molecular function

GO term

Evidence

Neuro keywords

PubMed ID

GO:0005515

protein binding

NAS

10653696

Biological process

GO term

Evidence

Neuro keywords

PubMed ID

GO:0007216

metabotropic glutamate receptor signaling pathway

TAS

glutamate (GO term level: 8)

9808458

GO:0006605

protein targeting

TAS

10653696

Cellular component

GO term

Evidence

Neuro keywords

PubMed ID

GO:0045211

postsynaptic membrane

IEA

Synap, Neurotransmitter (GO term level: 5)

GO:0045202

synapse

IEA

neuron, Synap, Neurotransmitter, Glial (GO term level: 2)

GO:0005575

cellular_component

GO:0005737

cytoplasm

IEA

GO:0005886

plasma membrane

IEA

GO:0030054

cell junction

IEA

Protein-protein Interactions

Shown by network

Interactors	Aliases B	Official full name B	Experimental	Source	PubMed ID
DYNLL2	DNCL1B \| Dlc2 \| MGC17810	dynein, light chain, LC8-type 2	Two-hybrid	BioGRID	16189514
FRYL	DKFZp686E205 \| FLJ16177 \| KIAA0826	FRY-like	Two-hybrid	BioGRID	16189514
GRM5	GPRC1E \| MGLUR5 \| MGLUR5A \| MGLUR5B \| mGlu5	glutamate receptor, metabotropic 5	Homer 3 interacts with GRM5 (mGluR5). This interaction was modeled on a demonstrated interaction between human Homer 3 and GRM5 from an unspecified species.	BIND	9808458
HOMER1	HOMER \| HOMER1A \| HOMER1B \| HOMER1C \| SYN47 \| Ves-1	homer homolog 1 (Drosophila)	-	HPRD	9808458
ITPR1	INSP3R1 \| IP3R \| IP3R1 \| SCA15 \| SCA16	inositol 1,4,5-triphosphate receptor, type 1	in vitro in vivo	BioGRID	9808459
RYR1	CCO \| MHS \| MHS1 \| RYDR \| RYR \| SKRR	ryanodine receptor 1 (skeletal)	-	HPRD,BioGRID	12223488
TRPC1	HTRP-1 \| MGC133334 \| MGC133335 \| TRP1	transient receptor potential cation channel, subfamily C, member 1	Affinity Capture-Western Reconstituted Complex	BioGRID	14505576
TRPC4	HTRP4 \| MGC119570 \| MGC119571 \| MGC119572 \| MGC119573 \| TRP4	transient receptor potential cation channel, subfamily C, member 4	Affinity Capture-Western	BioGRID	14505576
TRPC5	TRP5	transient receptor potential cation channel, subfamily C, member 5	Affinity Capture-Western	BioGRID	14505576

miRNA Targets ?

miRNA family	Target position			miRNA ID	miRNA seq
miRNA family	UTR start	UTR end	Match method	miRNA ID	miRNA seq
miR-203.1	226	232	m8	hsa-miR-203	UGAAAUGUUUAGGACCACUAG

SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.