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GeneID |
9507
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Symbol |
ADAMTS4
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Synonyms |
ADAMTS-2|ADAMTS-4|ADMP-1|KIAA0688
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Description |
ADAM metallopeptidase with thrombospondin type 1 motif, 4 |
See related |
HGNC:220|MIM:603876|Ensembl:ENSG00000158859|HPRD:04853| |
Locus tag |
- |
Gene type |
protein-coding |
Map location |
1q21-q23 |
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Gene set name |
Method of gene set |
Evidence |
Info |
GSMA_IIA | genome scan meta-analysis (All samples) | Psr: 0.00814 | | Literature | High-throughput literature-search | Co-occurance with Schizophrenia keywords: [schizophrenias, schizophrenia] | Click to show detail | Network | Shortest path distance of core genes in the Human protein-protein interaction network | Contribution to shortest path in PPI network: 0.2098 | |
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General Gene Expression (microarray) ? |
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Gene Expression in Brain Regions (new) |
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Top co-expressed genes in Brain Regions (new) |
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Gene | Pearson's Correlation | Spearman's Correlation | | |
Top 10 positively co-expressed genes |
TAPBP | 0.80 | 0.75 | | |
SHANK3 | 0.79 | 0.81 | | |
GALNT9 | 0.79 | 0.73 | | |
KNDC1 | 0.78 | 0.81 | | |
PIGZ | 0.78 | 0.80 | | |
GPR123 | 0.78 | 0.79 | | |
LPCAT4 | 0.77 | 0.79 | | |
TNK2 | 0.77 | 0.78 | | |
LENG3 | 0.77 | 0.77 | | |
SNAI3 | 0.77 | 0.78 | | |
Top 10 negatively co-expressed genes | RPS20 | -0.48 | -0.59 | | |
C9orf46 | -0.48 | -0.50 | | |
TPT1 | -0.47 | -0.48 | | |
RPL24 | -0.46 | -0.50 | | |
RPS6 | -0.46 | -0.50 | | |
SNRPG | -0.46 | -0.55 | | |
RPL31 | -0.45 | -0.48 | | |
RPS3AP47 | -0.45 | -0.44 | | |
RPL27 | -0.44 | -0.47 | | |
RPL35A | -0.44 | -0.54 | | |
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Molecular function | GO term | Evidence | Neuro keywords | PubMed ID |
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GO:0002020 | protease binding | IPI | | 14744861 |
GO:0004222 | metalloendopeptidase activity | IEA | | - |
GO:0008270 | zinc ion binding | IEA | | - |
GO:0008233 | peptidase activity | TAS | | 10751421 |
GO:0046872 | metal ion binding | IEA | | - |
Biological process | GO term | Evidence | Neuro keywords | PubMed ID |
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GO:0001501 | skeletal system development | TAS | | 10356395 |
GO:0006508 | proteolysis | IEA | | - |
GO:0006508 | proteolysis | TAS | | 10751421 |
Cellular component | GO term | Evidence | Neuro keywords | PubMed ID |
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GO:0005576 | extracellular region | IEA | | - |
GO:0005578 | proteinaceous extracellular matrix | IEA | | - |
GO:0005615 | extracellular space | IDA | | 14744861 |
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- SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
- Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.
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