Gene Page: CD48

Summary
GeneID  962
Symbol  CD48
Synonyms  BCM1|BLAST|BLAST1|MEM-102|SLAMF2|hCD48|mCD48
Description  CD48 molecule
See related  HGNC:1683|MIM:109530|Ensembl:ENSG00000117091|HPRD:00177|
Locus tag  -
Gene type  protein-coding
Map location  1q21.3-q22
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_Igenome scan meta-analysisPsr: 0.0235 
GSMA_IIAgenome scan meta-analysis (All samples)Psr: 0.00814 
LiteratureHigh-throughput literature-searchCo-occurance with Schizophrenia keywords: [schizophrenias, schizophrenia]Click to show detail
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
PTPMT10.790.77
RHOC0.790.75
MGMT0.750.72
HINT20.740.72
SRI0.740.74
CIB10.740.72
SLC27A50.740.75
HDDC20.740.71
GMFG0.730.69
S100A60.730.73
Top 10 negatively co-expressed genes
UPF2-0.60-0.62
BAZ2A-0.60-0.64
KIAA0240-0.59-0.59
MACF1-0.58-0.61
ZZEF1-0.58-0.60
TNRC6C-0.58-0.61
GON4L-0.58-0.58
HERC1-0.58-0.58
BOD1L-0.57-0.60
TULP4-0.57-0.60
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005515protein bindingIPI12356317 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006952defense responseTAS2828034 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005886plasma membraneTAS2828034 
GO:0005887integral to plasma membraneTAS1693656 
GO:0031225anchored to membraneIEA-
GO:0045121membrane raftIDA11313396 
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
BXDC2BRIX | FLJ11100brix domain containing 2Two-hybridBioGRID16169070 
CD2SRBC | T11CD2 molecule-HPRD,BioGRID12356317 
CD2442B4 | NAIL | NKR2B4 | Nmrk | SLAMF4CD244 molecule, natural killer cell receptor 2B4-HPRD9834056 |11163399 
EEF1DEF-1D | EF1D | FLJ20897 | FP1047eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)Two-hybridBioGRID16169070 
FYNMGC45350 | SLK | SYNFYN oncogene related to SRC, FGR, YES-HPRD8104794 
GNAI387U6 | FLJ26559guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3-HPRD8650218 
LCKYT16 | p56lck | pp58lcklymphocyte-specific protein tyrosine kinase-HPRD,BioGRID12007789 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_NATURAL_KILLER_CELL_MEDIATED_CYTOTOXICITY 13792All SZGR genes in this pathway
REACTOME_CELL_SURFACE_INTERACTIONS_AT_THE_VASCULAR_WALL 9165All SZGR genes in this pathway
REACTOME_HEMOSTASIS 466331All SZGR genes in this pathway
WINTER_HYPOXIA_DN 5230All SZGR genes in this pathway
GARY_CD5_TARGETS_UP 473314All SZGR genes in this pathway
DEURIG_T_CELL_PROLYMPHOCYTIC_LEUKEMIA_DN 320184All SZGR genes in this pathway
OSMAN_BLADDER_CANCER_UP 404246All SZGR genes in this pathway
TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_HSC_DN 187115All SZGR genes in this pathway
SABATES_COLORECTAL_ADENOMA_DN 291176All SZGR genes in this pathway
GAUSSMANN_MLL_AF4_FUSION_TARGETS_G_UP 238135All SZGR genes in this pathway
RASHI_RESPONSE_TO_IONIZING_RADIATION_6 8454All SZGR genes in this pathway
FARMER_BREAST_CANCER_CLUSTER_1 4423All SZGR genes in this pathway
AMUNDSON_GENOTOXIC_SIGNATURE 10568All SZGR genes in this pathway
PUJANA_ATM_PCC_NETWORK 1442892All SZGR genes in this pathway
ALCALA_APOPTOSIS 8860All SZGR genes in this pathway
FLECHNER_BIOPSY_KIDNEY_TRANSPLANT_REJECTED_VS_OK_UP 8758All SZGR genes in this pathway
WIELAND_UP_BY_HBV_INFECTION 10166All SZGR genes in this pathway
BYSTRYKH_HEMATOPOIESIS_STEM_CELL_QTL_TRANS 882572All SZGR genes in this pathway
PENG_RAPAMYCIN_RESPONSE_UP 203130All SZGR genes in this pathway
SANSOM_APC_TARGETS_DN 366238All SZGR genes in this pathway
BROWN_MYELOID_CELL_DEVELOPMENT_DN 12986All SZGR genes in this pathway
ALCALAY_AML_BY_NPM1_LOCALIZATION_DN 184132All SZGR genes in this pathway
VERHAAK_AML_WITH_NPM1_MUTATED_DN 246180All SZGR genes in this pathway
SCHURINGA_STAT5A_TARGETS_DN 1810All SZGR genes in this pathway
MCLACHLAN_DENTAL_CARIES_UP 253147All SZGR genes in this pathway
KRIGE_RESPONSE_TO_TOSEDOSTAT_6HR_UP 953554All SZGR genes in this pathway
KRIGE_RESPONSE_TO_TOSEDOSTAT_24HR_UP 783442All SZGR genes in this pathway
GAVIN_FOXP3_TARGETS_CLUSTER_T4 9469All SZGR genes in this pathway
MARSON_BOUND_BY_FOXP3_UNSTIMULATED 1229713All SZGR genes in this pathway
HELLER_HDAC_TARGETS_DN 292189All SZGR genes in this pathway
HELLER_HDAC_TARGETS_SILENCED_BY_METHYLATION_DN 281179All SZGR genes in this pathway
WALLACE_PROSTATE_CANCER_RACE_UP 299167All SZGR genes in this pathway
SMID_BREAST_CANCER_LUMINAL_B_DN 564326All SZGR genes in this pathway
SMID_BREAST_CANCER_NORMAL_LIKE_UP 476285All SZGR genes in this pathway
WILENSKY_RESPONSE_TO_DARAPLADIB 2920All SZGR genes in this pathway
CHAUHAN_RESPONSE_TO_METHOXYESTRADIOL_DN 10265All SZGR genes in this pathway
GOLDRATH_ANTIGEN_RESPONSE 346192All SZGR genes in this pathway
LINDSTEDT_DENDRITIC_CELL_MATURATION_A 6752All SZGR genes in this pathway
YOSHIMURA_MAPK8_TARGETS_DN 366257All SZGR genes in this pathway
RUTELLA_RESPONSE_TO_CSF2RB_AND_IL4_DN 315201All SZGR genes in this pathway
RUTELLA_RESPONSE_TO_HGF_DN 235144All SZGR genes in this pathway
RUTELLA_RESPONSE_TO_HGF_VS_CSF2RB_AND_IL4_UP 408276All SZGR genes in this pathway
LEE_DIFFERENTIATING_T_LYMPHOCYTE 200115All SZGR genes in this pathway
FINAK_BREAST_CANCER_SDPP_SIGNATURE 2611All SZGR genes in this pathway
CHEN_METABOLIC_SYNDROM_NETWORK 1210725All SZGR genes in this pathway
CROONQUIST_NRAS_SIGNALING_UP 4124All SZGR genes in this pathway
POOLA_INVASIVE_BREAST_CANCER_UP 288168All SZGR genes in this pathway
CHEN_LIVER_METABOLISM_QTL_CIS 9340All SZGR genes in this pathway
HOSHIDA_LIVER_CANCER_LATE_RECURRENCE_UP 6242All SZGR genes in this pathway
HOSHIDA_LIVER_CANCER_SURVIVAL_UP 7349All SZGR genes in this pathway
HOSHIDA_LIVER_CANCER_SUBCLASS_S1 237159All SZGR genes in this pathway
DANG_REGULATED_BY_MYC_DN 253192All SZGR genes in this pathway
WANG_RESPONSE_TO_GSK3_INHIBITOR_SB216763_UP 397206All SZGR genes in this pathway
FIGUEROA_AML_METHYLATION_CLUSTER_1_DN 4830All SZGR genes in this pathway
FIGUEROA_AML_METHYLATION_CLUSTER_5_DN 5031All SZGR genes in this pathway
CHYLA_CBFA2T3_TARGETS_UP 387225All SZGR genes in this pathway
PILON_KLF1_TARGETS_DN 19721213All SZGR genes in this pathway
BRUINS_UVC_RESPONSE_VIA_TP53_GROUP_D 280158All SZGR genes in this pathway
ZWANG_TRANSIENTLY_UP_BY_2ND_EGF_PULSE_ONLY 1725838All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-314349m8hsa-miR-31AGGCAAGAUGCUGGCAUAGCUG
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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