Gene Page: CLINT1

Summary
GeneID  9685
Symbol  CLINT1
Synonyms  CLINT|ENTH|EPN4|EPNR|EPSINR|FLJ46753|KIAA0171
Description  clathrin interactor 1
See related  HGNC:23186|MIM:607265|HPRD:06273|
Locus tag  -
Gene type  protein-coding
Map location  5q33.3
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
AssociationA combined odds ratio method (Sun et al. 2008), association studies3Link to SZGene
GSMA_Igenome scan meta-analysisPsr: 0.0032 
GSMA_IIEgenome scan meta-analysis (European-ancestry samples)Psr: 0.01718 
GSMA_IIAgenome scan meta-analysis (All samples)Psr: 0.00459 
LiteratureHigh-throughput literature-searchCo-occurance with Schizophrenia keywords: [schizophrenias, schizophrenia]Click to show detail
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
SNAP910.940.95
WDR70.930.92
PRKAR1A0.920.92
ATP6V1A0.920.92
PNMA20.910.92
PLEKHB20.900.91
USP320.900.90
RTN30.900.89
CLTC0.900.90
KIAA14670.900.91
Top 10 negatively co-expressed genes
RAB34-0.57-0.63
C1orf61-0.55-0.67
ACSF2-0.53-0.54
AP002478.3-0.52-0.56
AF347015.21-0.52-0.48
EIF4EBP3-0.51-0.56
PLA2G5-0.51-0.45
C1orf54-0.51-0.54
HIGD1B-0.51-0.48
AC098691.2-0.50-0.53
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005515protein bindingIPI14675752 
GO:0008289lipid bindingIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006897endocytosisIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005794Golgi apparatusIDA10942595 
GO:0005737cytoplasmIEA-
GO:0016020membraneIEA-
GO:0031410cytoplasmic vesicleIEA-
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
AP1B1ADTB1 | AP105A | BAM22 | CLAPB2adaptor-related protein complex 1, beta 1 subunitReconstituted ComplexBioGRID12429846 
AP1G1ADTG | CLAPG1 | MGC18255adaptor-related protein complex 1, gamma 1 subunit-HPRD,BioGRID12429846 
AP2A1ADTAA | AP2-ALPHA | CLAPA1adaptor-related protein complex 2, alpha 1 subunit-HPRD,BioGRID12429846 
AP2B1ADTB2 | AP105B | AP2-BETA | CLAPB1 | DKFZp781K0743adaptor-related protein complex 2, beta 1 subunit-HPRD,BioGRID12429846 
CLTCCHC | CHC17 | CLH-17 | CLTCL2 | Hc | KIAA0034clathrin, heavy chain (Hc)-HPRD,BioGRID12429846 
DNM1DNMdynamin 1Reconstituted ComplexBioGRID12429846 
EPS15AF-1P | AF1P | MLLT5epidermal growth factor receptor pathway substrate 15Reconstituted ComplexBioGRID12429846 
GGA2FLJ20966 | KIAA1080 | VEARgolgi associated, gamma adaptin ear containing, ARF binding protein 2-HPRD,BioGRID12213833 |12429846 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
ONKEN_UVEAL_MELANOMA_UP 783507All SZGR genes in this pathway
LAIHO_COLORECTAL_CANCER_SERRATED_UP 11271All SZGR genes in this pathway
BASAKI_YBX1_TARGETS_DN 384230All SZGR genes in this pathway
ZHOU_INFLAMMATORY_RESPONSE_FIMA_UP 544308All SZGR genes in this pathway
BARRIER_CANCER_RELAPSE_NORMAL_SAMPLE_UP 3221All SZGR genes in this pathway
SCHLOSSER_SERUM_RESPONSE_DN 712443All SZGR genes in this pathway
DACOSTA_UV_RESPONSE_VIA_ERCC3_DN 855609All SZGR genes in this pathway
PUJANA_BRCA1_PCC_NETWORK 16521023All SZGR genes in this pathway
PUJANA_BRCA2_PCC_NETWORK 423265All SZGR genes in this pathway
PUJANA_ATM_PCC_NETWORK 1442892All SZGR genes in this pathway
NUYTTEN_NIPP1_TARGETS_DN 848527All SZGR genes in this pathway
SHEN_SMARCA2_TARGETS_UP 424268All SZGR genes in this pathway
FLECHNER_BIOPSY_KIDNEY_TRANSPLANT_REJECTED_VS_OK_DN 546351All SZGR genes in this pathway
IVANOVA_HEMATOPOIESIS_LATE_PROGENITOR 544307All SZGR genes in this pathway
GENTILE_UV_RESPONSE_CLUSTER_D4 5537All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_14HR_UP 156101All SZGR genes in this pathway
TAKAO_RESPONSE_TO_UVB_RADIATION_DN 9867All SZGR genes in this pathway
GENTILE_UV_HIGH_DOSE_DN 312203All SZGR genes in this pathway
SESTO_RESPONSE_TO_UV_C5 4636All SZGR genes in this pathway
CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_3 720440All SZGR genes in this pathway
WEST_ADRENOCORTICAL_TUMOR_UP 294199All SZGR genes in this pathway
YAGI_AML_WITH_T_8_21_TRANSLOCATION 368247All SZGR genes in this pathway
DANG_BOUND_BY_MYC 1103714All SZGR genes in this pathway
KIM_ALL_DISORDERS_OLIGODENDROCYTE_NUMBER_CORR_UP 756494All SZGR genes in this pathway
KIM_ALL_DISORDERS_CALB1_CORR_UP 548370All SZGR genes in this pathway
PHESSE_TARGETS_OF_APC_AND_MBD2_UP 2014All SZGR genes in this pathway
BAKKER_FOXO3_TARGETS_DN 187109All SZGR genes in this pathway
WAKABAYASHI_ADIPOGENESIS_PPARG_BOUND_36HR 2923All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-137100710131Ahsa-miR-137UAUUGCUUAAGAAUACGCGUAG
miR-1455455521A,m8hsa-miR-145GUCCAGUUUUCCCAGGAAUCCCUU
miR-155113411401Ahsa-miR-155UUAAUGCUAAUCGUGAUAGGGG
miR-221/222105710631Ahsa-miR-221brainAGCUACAUUGUCUGCUGGGUUUC
hsa-miR-222brainAGCUACAUCUGGCUACUGGGUCUC
miR-33117311791Ahsa-miR-33GUGCAUUGUAGUUGCAUUG
hsa-miR-33bGUGCAUUGCUGUUGCAUUGCA
miR-433-3p11531159m8hsa-miR-433brainAUCAUGAUGGGCUCCUCGGUGU
miR-505126512711Ahsa-miR-505GUCAACACUUGCUGGUUUCCUC
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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