Gene Page: GFPT2

Summary
GeneID  9945
Symbol  GFPT2
Synonyms  FLJ10380|GFAT2
Description  glutamine-fructose-6-phosphate transaminase 2
See related  HGNC:4242|MIM:603865|Ensembl:ENSG00000131459|HPRD:04842|
Locus tag  -
Gene type  protein-coding
Map location  5q34-q35
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_IIAgenome scan meta-analysis (All samples)Psr: 0.0276 
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 1 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
ARHGAP200.770.80
JAZF10.760.78
TM6SF10.750.79
HIVEP20.740.77
DLG20.740.80
PRPS20.740.79
PTCHD10.740.77
PCDHA50.740.75
CDH100.740.79
PVRL30.740.73
Top 10 negatively co-expressed genes
C11orf67-0.49-0.51
AC098691.2-0.47-0.54
RAB34-0.46-0.51
FXYD1-0.46-0.38
AP002478.3-0.45-0.47
ACSF2-0.45-0.46
SLC2A4RG-0.45-0.45
AC021016.1-0.44-0.41
HSD17B14-0.44-0.43
AL138743.2-0.44-0.48
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0004360glutamine-fructose-6-phosphate transaminase (isomerizing) activityTASglutamate (GO term level: 6)10198162 
GO:0005529sugar bindingIEA-
GO:0016740transferase activityIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0016051carbohydrate biosynthetic processIEA-
GO:0006112energy reserve metabolic processTAS10198162 
GO:0006002fructose 6-phosphate metabolic processTAS10198162 
GO:0008152metabolic processIEA-
GO:0006541glutamine metabolic processIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005737cytoplasmIEA-
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_ALANINE_ASPARTATE_AND_GLUTAMATE_METABOLISM 3226All SZGR genes in this pathway
KEGG_AMINO_SUGAR_AND_NUCLEOTIDE_SUGAR_METABOLISM 4430All SZGR genes in this pathway
REACTOME_METABOLISM_OF_PROTEINS 518242All SZGR genes in this pathway
REACTOME_POST_TRANSLATIONAL_PROTEIN_MODIFICATION 188116All SZGR genes in this pathway
REACTOME_SYNTHESIS_OF_SUBSTRATES_IN_N_GLYCAN_BIOSYTHESIS 148All SZGR genes in this pathway
REACTOME_ASPARAGINE_N_LINKED_GLYCOSYLATION 8154All SZGR genes in this pathway
REACTOME_BIOSYNTHESIS_OF_THE_N_GLYCAN_PRECURSOR_DOLICHOL_LIPID_LINKED_OLIGOSACCHARIDE_LLO_AND_TRANSFER_TO_A_NASCENT_PROTEIN 2917All SZGR genes in this pathway
SCHUETZ_BREAST_CANCER_DUCTAL_INVASIVE_UP 351230All SZGR genes in this pathway
CHARAFE_BREAST_CANCER_LUMINAL_VS_MESENCHYMAL_DN 460312All SZGR genes in this pathway
CHARAFE_BREAST_CANCER_BASAL_VS_MESENCHYMAL_DN 5036All SZGR genes in this pathway
VECCHI_GASTRIC_CANCER_ADVANCED_VS_EARLY_UP 175120All SZGR genes in this pathway
SENESE_HDAC1_AND_HDAC2_TARGETS_UP 238144All SZGR genes in this pathway
SENESE_HDAC2_TARGETS_UP 11466All SZGR genes in this pathway
SENESE_HDAC3_TARGETS_UP 501327All SZGR genes in this pathway
KIM_WT1_TARGETS_UP 214155All SZGR genes in this pathway
KIM_WT1_TARGETS_8HR_UP 164122All SZGR genes in this pathway
KAN_RESPONSE_TO_ARSENIC_TRIOXIDE 12380All SZGR genes in this pathway
PEREZ_TP63_TARGETS 355243All SZGR genes in this pathway
DAUER_STAT3_TARGETS_UP 4935All SZGR genes in this pathway
HATADA_METHYLATED_IN_LUNG_CANCER_UP 390236All SZGR genes in this pathway
NUYTTEN_EZH2_TARGETS_UP 1037673All SZGR genes in this pathway
AMIT_EGF_RESPONSE_240_HELA 6043All SZGR genes in this pathway
BLALOCK_ALZHEIMERS_DISEASE_UP 16911088All SZGR genes in this pathway
STEIN_ESRRA_TARGETS_UP 388234All SZGR genes in this pathway
OUILLETTE_CLL_13Q14_DELETION_DN 6038All SZGR genes in this pathway
RIGGI_EWING_SARCOMA_PROGENITOR_DN 191123All SZGR genes in this pathway
ZHANG_BREAST_CANCER_PROGENITORS_DN 14593All SZGR genes in this pathway
BOQUEST_STEM_CELL_UP 260174All SZGR genes in this pathway
FONTAINE_FOLLICULAR_THYROID_ADENOMA_DN 6845All SZGR genes in this pathway
FONTAINE_PAPILLARY_THYROID_CARCINOMA_DN 8053All SZGR genes in this pathway
STEIN_ESRRA_TARGETS 535325All SZGR genes in this pathway
TIAN_TNF_SIGNALING_VIA_NFKB 2821All SZGR genes in this pathway
MARTENS_TRETINOIN_RESPONSE_UP 857456All SZGR genes in this pathway
CHICAS_RB1_TARGETS_SENESCENT 572352All SZGR genes in this pathway
JOHNSTONE_PARVB_TARGETS_3_UP 430288All SZGR genes in this pathway
MIYAGAWA_TARGETS_OF_EWSR1_ETS_FUSIONS_DN 229135All SZGR genes in this pathway
IKEDA_MIR30_TARGETS_UP 11687All SZGR genes in this pathway
PLASARI_TGFB1_TARGETS_10HR_UP 199143All SZGR genes in this pathway
PHONG_TNF_RESPONSE_NOT_VIA_P38 337236All SZGR genes in this pathway
FOSTER_KDM1A_TARGETS_DN 211119All SZGR genes in this pathway
ZWANG_CLASS_2_TRANSIENTLY_INDUCED_BY_EGF 5129All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-124/506136142m8hsa-miR-506UAAGGCACCCUUCUGAGUAGA
hsa-miR-124brainUAAGGCACGCGGUGAAUGCC
miR-1282872931Ahsa-miR-128aUCACAGUGAACCGGUCUCUUUU
hsa-miR-128bUCACAGUGAACCGGUCUCUUUC
miR-1434694761A,m8hsa-miR-143brainUGAGAUGAAGCACUGUAGCUCA
miR-1538308371A,m8hsa-miR-153UUGCAUAGUCACAAAAGUGA
miR-2198178231Ahsa-miR-219brainUGAUUGUCCAAACGCAAUUCU
miR-25/32/92/363/3672562631A,m8hsa-miR-25brainCAUUGCACUUGUCUCGGUCUGA
hsa-miR-32UAUUGCACAUUACUAAGUUGC
hsa-miR-92UAUUGCACUUGUCCCGGCCUG
hsa-miR-367AAUUGCACUUUAGCAAUGGUGA
hsa-miR-92bSZUAUUGCACUCGUCCCGGCCUC
miR-272872941A,m8hsa-miR-27abrainUUCACAGUGGCUAAGUUCCGC
hsa-miR-27bbrainUUCACAGUGGCUAAGUUCUGC
miR-30-5p2172241A,m8hsa-miR-30a-5pUGUAAACAUCCUCGACUGGAAG
hsa-miR-30cbrainUGUAAACAUCCUACACUCUCAGC
hsa-miR-30dSZUGUAAACAUCCCCGACUGGAAG
hsa-miR-30bSZUGUAAACAUCCUACACUCAGCU
hsa-miR-30e-5pUGUAAACAUCCUUGACUGGA
miR-4488318371Ahsa-miR-448UUGCAUAUGUAGGAUGUCCCAU
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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