| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
|
|---|---|
Gene ID | 10018 |
Name | BCL2L11 |
Synonym | BAM|BIM|BOD;BCL2-like 11 (apoptosis facilitator);BCL2L11;BCL2-like 11 (apoptosis facilitator) |
Definition | bcl-2 interacting mediator of cell death|bcl-2 interacting protein Bim|bcl-2-like protein 11|bcl-2-related ovarian death agonist |
Position | 2q13 |
Gene Type | protein-coding |
|
TSG scores |
Description |
| TUSON ranking | 3426 |
TUSON P-value | 1 |
|
Pathways and Diseases |
|
Pathway | Apoptosis;Reactome;REACT:578 |
Pathway | p75(NTR)-mediated signaling;PID Curated;200103 |
Pathway | Apoptosis signaling pathway;PANTHER;P00006 |
Pathway | AP-1 transcription factor network;PID Curated;200118 |
Pathway | FoxO family signaling;PID Curated;200091 |
Pathway | Signalling by NGF;Reactome;REACT:11061 |
Pathway | Activation of BIM and translocation to mitochondria;PID Reactome;500262 |
Disease | Vaccinia;FunDO |
Disease | Chronic lymphocytic leukemia;GAD |
Disease | Lymphoma;FunDO |
Disease | CANCER;GAD |
Disease | Cancer;FunDO |
Disease | Gram-Negative bacterial infection;FunDO |
|
External Links |
|
Links to Entrez Gene | 10018 |
Links to all GeneRIF Items | 10018 |
Links to iHOP | 10018 |
|
Sequence Information |
The sequences provided here are only the longest representative sequences, not covering all the isoforms. |
Nucleotide Sequence |
>10018 : length: 327 atggcaaagcaaccttctgatgtaagttctgagtgtgaccgagaaggtagacaattgcag cctgcggagaggcctccccagctcagacctggggcccctacctccctacagacagagcca caagcttccatgaggcaggctgaacctgcagatatgcgcccagagatatggatcgcccaa gagttgcggcgtattggagacgagtttaacgcttactatgcaaggagggtatttttgaat aattaccaagcagccgaagaccacccacgaatggttatcttacgactgttacgttacatt gtccgcctggtgtggagaatgcattga |
Protein Sequence |
>10018 : length: 108 MAKQPSDVSSECDREGRQLQPAERPPQLRPGAPTSLQTEPQASMRQAEPADMRPEIWIAQ ELRRIGDEFNAYYARRVFLNNYQAAEDHPRMVILRLLRYIVRLVWRMH |