Entrez Gene

Basic Information
Gene ID	10018
Name	BCL2L11
Synonymous	BAM\|BIM\|BOD;BCL2-like 11 (apoptosis facilitator);BCL2L11;BCL2-like 11 (apoptosis facilitator)
Definition	bcl-2 interacting mediator of cell death\|bcl-2 interacting protein Bim\|bcl-2-like protein 11\|bcl-2-related ovarian death agonist
Position	2q13
Gene Type	protein-coding
Gene Regulation:	Upstream microRNAs Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database

Experimentally verified miRNA from miRTarBase [Top]

Regulation From TransFac database
Transcription Factors [Top]
BimEL(h) + Bcl-2(h) <==> BimEL(h):Bcl-2(h) (binding)
Mcl-1L(h) + BimEL(h) <==> Mcl-1L(h):BimEL(h) (binding)
Mcl-1S(h) + BimEL(h) <==> Mcl-1S(h):BimEL(h) (binding)
BCL2L11(h) --> BimEL(h) (expression).
BimL(h) + LC8(h) <==> BimL(h):LC8(h) (binding)
BimL(h) + ATP --JNK1(h)--> BimL(h){p} + ADP (phosphorylation)
Mcl-1L(h) + BimL(h) <==> Mcl-1L(h):BimL(h) (binding)
BCL2L11(h) --> BimL(h) (expression).
Mcl-1(h) + Bim(h) <==> Mcl-1(h):Bim(h) (binding)
Bim(h) + ATP --> Bim(h){p} + ADP (phosphorylation)
BCL2L11(h) --> Bim(h) (expression).
FOXO1A(m.s.) --> Bim(h) (increase of abundance)
ERK(h) --/ Bim(h) (decrease of abundance)
FOXO3a(m.s.) --> Bim(h) (increase of abundance)
BimAD(h) + Bcl-2(h) <==> BimAD(h):Bcl-2(h) (binding)
BimAD(h) + Bax(h) <==> BimAD(h):Bax(h) (binding)
BCL2L11(h) --> BimAD(h) (expression).
BimS(h) + Bcl-2(h) <==> BimS(h):Bcl-2(h) (binding)
BimS(h) + Bax(h) <==> BimS(h):Bax(h) (binding)
Mcl-1L(h) + BimS(h) <==> Mcl-1L(h):BimS(h) (binding)
BCL2L11(h) --> BimS(h) (expression).

Post Transcriptional Modification [Top]
	There is no record for BCL2L11