| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
|
|---|---|
Gene ID | 10019 |
Name | SH2B3 |
Synonym | IDDM20|LNK;SH2B adaptor protein 3;SH2B3;SH2B adaptor protein 3 |
Definition | SH2B adapter protein 3|lymphocyte-specific adapter protein Lnk|signal transduction protein Lnk |
Position | 12q24 |
Gene Type | protein-coding |
|
TSG scores |
Description |
| TUSON ranking | 14862 |
TUSON P-value | 1 |
|
Pathways and Diseases |
|
Pathway | EPO signaling pathway;PID Curated;200157 |
Pathway | Signaling events mediated by Stem cell factor receptor (c-Kit);PID Curated;200156 |
Pathway | Neurotrophin signaling pathway;KEGG PATHWAY;hsa04722 |
Disease | Hematocrit;NHGRI |
Disease | IMMUNE;GAD |
Disease | Metabolic diseases;KEGG DISEASE |
Disease | Type 1 diabetes;NHGRI |
Disease | Plasma eosinophil count;NHGRI |
Disease | Celiac disease;NHGRI |
Disease | HEMATOLOGICAL;GAD |
Disease | type 1 diabetes;GAD |
Disease | Type I diabetes mellitus;KEGG DISEASE;H00408 |
Disease | Celiac Disease;GAD |
Disease | Systolic blood pressure;NHGRI |
Disease | CARDIOVASCULAR;GAD |
Disease | Rheumatoid arthritis;NHGRI |
Disease | Diastolic blood pressure;GAD |
Disease | Diastolic blood pressure;NHGRI |
Disease | Diabetes;KEGG DISEASE |
Disease | hematocrit;GAD |
Disease | plasma eosinophil count;GAD |
Disease | systolic blood pressure;GAD |
|
External Links |
|
Links to Entrez Gene | 10019 |
Links to all GeneRIF Items | 10019 |
Links to iHOP | 10019 |
|
Sequence Information |
The sequences provided here are only the longest representative sequences, not covering all the isoforms. |
Nucleotide Sequence |
>10019 : length: 1728 atgaacgggcctgccctgcagccctcctcgccctcttccgcgccctcagcctccccggcg gcggccccgcggggctggagcgagttctgtgagttgcacgccgtagcggcggcccgggag ctggcccgccagtactggctgttcgcccgggagcatccgcagcacgcgccgctgcgcgcc gagctggtgtcgctgcagttcaccgacctcttccagcgctacttctgccgcgaggtgcgc gacggacgggcgccgggccgcgactaccgggacacaggccgtgggcccccagccaaggcc gaggcgtccccggagccaggccccggccccgccgcccctggcctgcccaaggcccgcagc tctgaggagctggccccgccgcggccgcccgggccctgctccttccagcactttcgccgc agcctccgccacatcttccgccgccgctcggccggggagctgccagcggcccacaccgct gccgcccccgggacccccggagaggctgctgagacccccgcccggcctggcctggccaag aagttcctgccctggagcctggcccgggagccgccacccgaggcgctgaaggaggcggtg ctgcgctacagcctggccgacgaggcctccatggacagcggggcacgctggcagcgcggg aggctggcgctgcgccgggccccgggccccgatggccccgaccgcgtgctggagctcttc gacccacccaagagttcaaggcccaagctacaagcagcttgctccagcatccaggaggtc cggtggtgcacacggcttgagatgcctgacaacctttacacctttgtgctgaaggtgaag gaccggacagacatcatctttgaggtgggagacgagcagcagctgaattcatggatggct gagctctcggagtgcacaggccgagggctggagagcacagaagcagagatgcatattccc tcagccctagagcctagcacgtccagctccccaaggggcagcacagattcccttaaccaa ggtgcttctcctggggggctgctggacccggcctgccagaagacggaccatttcctgtcc tgctacccctggttccacggccccatctccagagtgaaagcagctcagctggttcagctg cagggccctgatgctcatggagtgttcctggtgcggcagagcgagacgcggcgtggggaa tacgtgctcactttcaactttcaggggatagccaagcacctgcgcctgtcgctgacagag cggggccagtgccgtgtgcagcacctccactttccctcggtcgtggacatgctccaccac ttccagcgctcgcccatcccactcgagtgcggcgccgcctgtgatgtccggctctccagc tacgtggtagtcgtctcccaaccaccaggttcctgcaacacggtcctcttccctttctcc cttcctcactgggattcagagtcccttcctcactggggttcagagttgggccttccccac cttagttcttctggctgtccccgggggctcagcccagagggtctcccagggcgatcctca ccccccgagcagatcttccacctggtgccttcgcccgaagaactggccaacagcctgcag cacctggagcatgagcctgtgaatcgagcccgggactcggactacgaaatggactcatcc tcccggagccacctgcgggccatagacaatcagtacacacctctctga |
Protein Sequence |
>10019 : length: 575 MNGPALQPSSPSSAPSASPAAAPRGWSEFCELHAVAAARELARQYWLFAREHPQHAPLRA ELVSLQFTDLFQRYFCREVRDGRAPGRDYRDTGRGPPAKAEASPEPGPGPAAPGLPKARS SEELAPPRPPGPCSFQHFRRSLRHIFRRRSAGELPAAHTAAAPGTPGEAAETPARPGLAK KFLPWSLAREPPPEALKEAVLRYSLADEASMDSGARWQRGRLALRRAPGPDGPDRVLELF DPPKSSRPKLQAACSSIQEVRWCTRLEMPDNLYTFVLKVKDRTDIIFEVGDEQQLNSWMA ELSECTGRGLESTEAEMHIPSALEPSTSSSPRGSTDSLNQGASPGGLLDPACQKTDHFLS CYPWFHGPISRVKAAQLVQLQGPDAHGVFLVRQSETRRGEYVLTFNFQGIAKHLRLSLTE RGQCRVQHLHFPSVVDMLHHFQRSPIPLECGAACDVRLSSYVVVVSQPPGSCNTVLFPFS LPHWDSESLPHWGSELGLPHLSSSGCPRGLSPEGLPGRSSPPEQIFHLVPSPEELANSLQ HLEHEPVNRARDSDYEMDSSSRSHLRAIDNQYTPL |