| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
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|---|---|
Gene ID | 1003 |
Name | CDH5 |
Synonym | 7B4|CD144;cadherin 5, type 2 (vascular endothelium);CDH5;cadherin 5, type 2 (vascular endothelium) |
Definition | 7B4 antigen|VE-cadherin|cadherin 5, type 2, VE-cadherin (vascular epithelium)|cadherin-5|cd144 antigen|endothelial-specific cadherin|vascular endothelial cadherin |
Position | 16q22.1 |
Gene Type | protein-coding |
|
TSG scores |
Description |
| TUSON ranking | 4673 |
TUSON P-value | 1 |
|
Pathways and Diseases |
|
Pathway | Cell junction organization;Reactome;REACT:20676 |
Pathway | Signaling events mediated by VEGFR1 and VEGFR2;PID Curated;200161 |
Pathway | Wnt signaling pathway;PANTHER;P00057 |
Pathway | Cadherin signaling pathway;PANTHER;P00012 |
Pathway | S1P2 pathway;PID Curated;200181 |
Pathway | Cell adhesion molecules (CAMs);KEGG PATHWAY;hsa04514 |
Pathway | Leukocyte transendothelial migration;KEGG PATHWAY;hsa04670 |
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External Links |
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Links to Entrez Gene | 1003 |
Links to all GeneRIF Items | 1003 |
Links to iHOP | 1003 |
|
Sequence Information |
The sequences provided here are only the longest representative sequences, not covering all the isoforms. |
Nucleotide Sequence |
>1003 : length: 2355 atgcagaggctcatgatgctcctcgccacatcgggcgcctgcctgggcctgctggcagtg gcagcagtggcagcagcaggtgctaaccctgcccaacgggacacccacagcctgctgccc acccaccggcgccaaaagagagattggatttggaaccagatgcacattgatgaagagaaa aacacctcacttccccatcatgtaggcaagatcaagtcaagcgtgagtcgcaagaatgcc aagtacctgctcaaaggagaatatgtgggcaaggtcttccgggtcgatgcagagacagga gacgtgttcgccattgagaggctggaccgggagaatatctcagagtaccacctcactgct gtcattgtggacaaggacactggcgaaaacctggagactccttccagcttcaccatcaaa gttcatgacgtgaacgacaactggcctgtgttcacgcatcggttgttcaatgcgtccgtg cctgagtcgtcggctgtggggacctcagtcatctctgtgacagcagtggatgcagacgac cccactgtgggagaccacgcctctgtcatgtaccaaatcctgaaggggaaagagtatttt gccatcgataattctggacgtattatcacaataacgaaaagcttggaccgagagaagcag gccaggtatgagatcgtggtggaagcgcgagatgcccagggcctccggggggactcgggc acggccaccgtgctggtcactctgcaagacatcaatgacaacttccccttcttcacccag accaagtacacatttgtcgtgcctgaagacacccgtgtgggcacctctgtgggctctctg tttgttgaggacccagatgagccccagaaccggatgaccaagtacagcatcttgcggggc gactaccaggacgctttcaccattgagacaaaccccgcccacaacgagggcatcatcaag cccatgaagcctctggattatgaatacatccagcaatacagcttcatcgtcgaggccaca gaccccaccatcgacctccgatacatgagccctcccgcgggaaacagagcccaggtcatt atcaacatcacagatgtggacgagccccccattttccagcagcctttctaccacttccag ctgaaggaaaaccagaagaagcctctgattggcacagtgctggccatggaccctgatgcg gctaggcatagcattggatactccatccgcaggaccagtgacaagggccagttcttccga gtcacaaaaaagggggacatttacaatgagaaagaactggacagagaagtctacccctgg tataacctgactgtggaggccaaagaactggattccactggaacccccacaggaaaagaa tccattgtgcaagtccacattgaagttttggatgagaatgacaatgccccggagtttgcc aagccctaccagcccaaagtgtgtgagaacgctgtccatggccagctggtcctgcagatc tccgcaatagacaaggacataacaccacgaaacgtgaagttcaaattcatcttgaatact gagaacaactttaccctcacggataatcacgataacacggccaacatcacagtcaagtat gggcagtttgaccgggagcataccaaggtccacttcctacccgtggtcatctcagacaat gggatgccaagtcgcacgggcaccagcacgctgaccgtggccgtgtgcaagtgcaacgag cagggcgagttcaccttctgcgaggatatggccgcccaggtgggcgtgagcatccaggca gtggtagccatcttactctgcatcctcaccatcacagtgatcaccctgctcatcttcctg cggcggcggctccggaagcaggcccgcgcgcacggcaagagcgtgccggagatccacgag cagctggtcacctacgacgaggagggcggcggcgagatggacaccaccagctacgatgtg tcggtgctcaactcggtgcgccgcggcggggccaagcccccgcggcccgcgctggacgcc cggccttccctctatgcgcaggtgcagaagccaccgaggcacgcgcctggggcacacgga gggcccggggagatggcagccatgatcgaggtgaagaaggacgaggcggaccacgacggc gacggccccccctacgacacgctgcacatctacggctacgagggctccgagtccatagcc gagtccctcagctccctgggcaccgactcatccgactctgacgtggattacgacttcctt aacgactggggacccaggtttaagatgctggctgagctgtacggctcggacccccgggag gagctgctgtattag |
Protein Sequence |
>1003 : length: 784 MQRLMMLLATSGACLGLLAVAAVAAAGANPAQRDTHSLLPTHRRQKRDWIWNQMHIDEEK NTSLPHHVGKIKSSVSRKNAKYLLKGEYVGKVFRVDAETGDVFAIERLDRENISEYHLTA VIVDKDTGENLETPSSFTIKVHDVNDNWPVFTHRLFNASVPESSAVGTSVISVTAVDADD PTVGDHASVMYQILKGKEYFAIDNSGRIITITKSLDREKQARYEIVVEARDAQGLRGDSG TATVLVTLQDINDNFPFFTQTKYTFVVPEDTRVGTSVGSLFVEDPDEPQNRMTKYSILRG DYQDAFTIETNPAHNEGIIKPMKPLDYEYIQQYSFIVEATDPTIDLRYMSPPAGNRAQVI INITDVDEPPIFQQPFYHFQLKENQKKPLIGTVLAMDPDAARHSIGYSIRRTSDKGQFFR VTKKGDIYNEKELDREVYPWYNLTVEAKELDSTGTPTGKESIVQVHIEVLDENDNAPEFA KPYQPKVCENAVHGQLVLQISAIDKDITPRNVKFKFILNTENNFTLTDNHDNTANITVKY GQFDREHTKVHFLPVVISDNGMPSRTGTSTLTVAVCKCNEQGEFTFCEDMAAQVGVSIQA VVAILLCILTITVITLLIFLRRRLRKQARAHGKSVPEIHEQLVTYDEEGGGEMDTTSYDV SVLNSVRRGGAKPPRPALDARPSLYAQVQKPPRHAPGAHGGPGEMAAMIEVKKDEADHDG DGPPYDTLHIYGYEGSESIAESLSSLGTDSSDSDVDYDFLNDWGPRFKMLAELYGSDPRE ELLY |