| General information | Literature | Expression | Regulation | Variant | Interaction |
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Basic Information |
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|---|---|
Gene ID | 1003 |
Name | CDH5 |
Synonymous | 7B4|CD144;cadherin 5, type 2 (vascular endothelium);CDH5;cadherin 5, type 2 (vascular endothelium) |
Definition | 7B4 antigen|VE-cadherin|cadherin 5, type 2, VE-cadherin (vascular epithelium)|cadherin-5|cd144 antigen|endothelial-specific cadherin|vascular endothelial cadherin |
Position | 16q22.1 |
Gene Type | protein-coding |
Gene Regulation: | Upstream microRNAs Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database |
Experimentally verified miRNA from miRTarBase [Top] | |||
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Transcription Factors [Top] |
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Regulation From TransFac database |
VE-cadherin(h) + Csk(h) <==> VE-cadherin(h):Csk(h) (binding) | actin(h) + vimentin(h) + plakoglobin(h) + beta-catenin(h) + alpha-catenin(h) + VE-cadherin(h) <==> actin(h):vimentin(h):plakoglobin(h):beta-catenin(h):alpha-catenin(h):VE-cadherin(h) (binding) | plakoglobin(h) + alpha-catenin(h) + beta-catenin(h) + VE-cadherin(h) <==> plakoglobin(h):alpha-catenin(h):beta-catenin(h):VE-cadherin(h) (binding) | vimentin(h) + VE-cadherin(h) <==> vimentin(h):VE-cadherin(h) (binding) | VE-cadherin(h) + ATP --> VE-cadherin(h){p} + ADP (phosphorylation) | beta-catenin(h) + plakoglobin(h) + vimentin(h) + VE-cadherin(h) <==> beta-catenin(h):plakoglobin(h):vimentin(h):VE-cadherin(h) (binding) | VE-cadherin(h) + 3 ATP --> VE-cadherin(h){pY658}{pY685}{pY731} + 3 ADP (phosphorylation) | p120CAS(h) + VE-cadherin(h) <==> p120CAS(h):VE-cadherin(h) (binding) | beta-catenin(h) + VE-cadherin(h) <==> beta-catenin(h):VE-cadherin(h) (binding) | CDH5(h) --> VE-cadherin(h) (expression). | CDH5(h) --> VE-cadherin(h) (expression). |
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Post Transcriptional Modification [Top] | |||
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Location (AA) |
PTM type |
Literature |
Database |
61 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 112 | N-linked (GlcNAc...). | Swiss-Prot 53.0 | 157 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 362 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 442 | N-linked (GlcNAc...). | Swiss-Prot 53.0 | 523 | N-linked (GlcNAc...). | Swiss-Prot 53.0 | 535 | N-linked (GlcNAc...). | Swiss-Prot 53.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
There is no record for CDH5 | ||